SLC25A22 (solute carrier family 25 member 22)

2017-08-01  

Identity

HGNC
LOCATION
11p15.5
LOCUSID
ALIAS
DEE3,EIEE3,GC-1,GC1,NET44

Other Information

Locus ID:

NCBI: 79751
MIM: 609302
HGNC: 19954
Ensembl: ENSG00000177542

Variants:

dbSNP: 79751
ClinVar: 79751
TCGA: ENSG00000177542
COSMIC: SLC25A22

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000177542ENST00000320230Q9H936
ENSG00000177542ENST00000456706K4DIA2
ENSG00000177542ENST00000481290E9PJH7
ENSG00000177542ENST00000526152E9PI74
ENSG00000177542ENST00000527723E9PQ36
ENSG00000177542ENST00000527734E9PJY0
ENSG00000177542ENST00000528606K4DIB8
ENSG00000177542ENST00000528936K4DIB0
ENSG00000177542ENST00000529066A0A0A6YYN8
ENSG00000177542ENST00000529351E9PJY0
ENSG00000177542ENST00000530360K4DIB4
ENSG00000177542ENST00000531214Q9H936
ENSG00000177542ENST00000531437E9PS95
ENSG00000177542ENST00000531514E9PJY0
ENSG00000177542ENST00000531534K4DIB6
ENSG00000177542ENST00000532484K4DIA8
ENSG00000177542ENST00000533385K4DIB3
ENSG00000177542ENST00000625419A0A0D9SEI9
ENSG00000177542ENST00000625752A0A0D9SG84
ENSG00000177542ENST00000627843A0A0D9SFE1
ENSG00000177542ENST00000628067Q9H936
ENSG00000177542ENST00000629634A0A0D9SFA8

Expression (GTEx)

0
50
100
150
200

Pathways

PathwaySourceExternal ID
Transmembrane transport of small moleculesREACTOMER-HSA-382551
SLC-mediated transmembrane transportREACTOMER-HSA-425407
Transport of inorganic cations/anions and amino acids/oligopeptidesREACTOMER-HSA-425393
Organic anion transportersREACTOMER-HSA-428643

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
232661872013The mitochondrial transporter family SLC25: identification, properties and physiopathology.159
197807652009Mutations in the mitochondrial glutamate carrier SLC25A22 in neonatal epileptic encephalopathy with suppression bursts.33
245969482013SLC25A22 is a novel gene for migrating partial seizures in infancy.24
274511472016SLC25A22 Promotes Proliferation and Survival of Colorectal Cancer Cells With KRAS Mutations and Xenograft Tumor Progression in Mice via Intracellular Synthesis of Aspartate.24
282557792017Mutations in SLC25A22: hyperprolinaemia, vacuolated fibroblasts and presentation with developmental delay.4
304820972018SLC25A22 Promotes Proliferation and Metastasis of Osteosarcoma Cells via the PTEN Signaling Pathway.1

Citation

Dessen P

SLC25A22 (solute carrier family 25 member 22)

Atlas Genet Cytogenet Oncol Haematol. 2017-08-01

Online version: http://atlasgeneticsoncology.org/gene/57002/slc25a22