Atlas of Genetics and Cytogenetics in Oncology and Haematology


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SLC25A25 (solute carrier family 25 member 25)

Identity

Alias_namessolute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
Alias_symbol (synonym)KIAA1896
PCSCL
MCSC
Other aliasSCAMC-2
HGNC (Hugo) SLC25A25
LocusID (NCBI) 114789
Atlas_Id 73348
Location 9q34.11  [Link to chromosome band 9q34]
Location_base_pair Starts at 128068200 and ends at 128109258 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CDK6 (7q21.2) / SLC25A25 (9q34.11)SLC25A25 (9q34.11) / CIZ1 (9q34.11)SLC25A25 (9q34.11) / LYPLAL1 (1q41)
SLC25A25 (9q34.11) / SPINK5 (5q32)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SLC25A25   20663
Cards
Entrez_Gene (NCBI)SLC25A25  114789  solute carrier family 25 member 25
AliasesMCSC; PCSCL; SCAMC-2
GeneCards (Weizmann)SLC25A25
Ensembl hg19 (Hinxton)ENSG00000148339 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000148339 [Gene_View]  chr9:128068200-128109258 [Contig_View]  SLC25A25 [Vega]
ICGC DataPortalENSG00000148339
TCGA cBioPortalSLC25A25
AceView (NCBI)SLC25A25
Genatlas (Paris)SLC25A25
WikiGenes114789
SOURCE (Princeton)SLC25A25
Genetics Home Reference (NIH)SLC25A25
Genomic and cartography
GoldenPath hg38 (UCSC)SLC25A25  -     chr9:128068200-128109258 +  9q34.11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SLC25A25  -     9q34.11   [Description]    (hg19-Feb_2009)
EnsemblSLC25A25 - 9q34.11 [CytoView hg19]  SLC25A25 - 9q34.11 [CytoView hg38]
Mapping of homologs : NCBISLC25A25 [Mapview hg19]  SLC25A25 [Mapview hg38]
OMIM608745   
Gene and transcription
Genbank (Entrez)AB067483 AJ619963 AJ619989 AJ619990 AJ619991
RefSeq transcript (Entrez)NM_001006641 NM_001006642 NM_001006643 NM_001265614 NM_001330988 NM_052901
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SLC25A25
Cluster EST : UnigeneHs.729700 [ NCBI ]
CGAP (NCI)Hs.729700
Alternative Splicing GalleryENSG00000148339
Gene ExpressionSLC25A25 [ NCBI-GEO ]   SLC25A25 [ EBI - ARRAY_EXPRESS ]   SLC25A25 [ SEEK ]   SLC25A25 [ MEM ]
Gene Expression Viewer (FireBrowse)SLC25A25 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)114789
GTEX Portal (Tissue expression)SLC25A25
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6KCM7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6KCM7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6KCM7
Splice isoforms : SwissVarQ6KCM7
PhosPhoSitePlusQ6KCM7
Domaine pattern : Prosite (Expaxy)EF_HAND_2 (PS50222)    SOLCAR (PS50920)   
Domains : Interpro (EBI)EF-hand-dom_pair    EF_hand_dom    Graves_DC    Mit_carrier    Mitochondrial_sb/sol_carrier    Mt_carrier_dom   
Domain families : Pfam (Sanger)EF-hand_7 (PF13499)    EF-hand_8 (PF13833)    Mito_carr (PF00153)   
Domain families : Pfam (NCBI)pfam13499    pfam13833    pfam00153   
Domain families : Smart (EMBL)EFh (SM00054)  
Conserved Domain (NCBI)SLC25A25
DMDM Disease mutations114789
Blocks (Seattle)SLC25A25
SuperfamilyQ6KCM7
Human Protein AtlasENSG00000148339
Peptide AtlasQ6KCM7
HPRD10573
IPIIPI00411392   IPI00645318   IPI00432357   IPI00885125   IPI00289851   IPI00514194   IPI00945504   IPI00945246   
Protein Interaction databases
DIP (DOE-UCLA)Q6KCM7
IntAct (EBI)Q6KCM7
FunCoupENSG00000148339
BioGRIDSLC25A25
STRING (EMBL)SLC25A25
ZODIACSLC25A25
Ontologies - Pathways
QuickGOQ6KCM7
Ontology : AmiGOresponse to dietary excess  ATP transmembrane transporter activity  calcium ion binding  mitochondrial inner membrane  mitochondrial transport  response to activity  ADP transmembrane transporter activity  ADP transport  ATP transport  integral component of membrane  response to food  multicellular organism growth  camera-type eye development  cellular respiration  ATP metabolic process  adipose tissue development  extracellular exosome  calcium ion transmembrane transport  
Ontology : EGO-EBIresponse to dietary excess  ATP transmembrane transporter activity  calcium ion binding  mitochondrial inner membrane  mitochondrial transport  response to activity  ADP transmembrane transporter activity  ADP transport  ATP transport  integral component of membrane  response to food  multicellular organism growth  camera-type eye development  cellular respiration  ATP metabolic process  adipose tissue development  extracellular exosome  calcium ion transmembrane transport  
NDEx NetworkSLC25A25
Atlas of Cancer Signalling NetworkSLC25A25
Wikipedia pathwaysSLC25A25
Orthology - Evolution
OrthoDB114789
GeneTree (enSembl)ENSG00000148339
Phylogenetic Trees/Animal Genes : TreeFamSLC25A25
HOVERGENQ6KCM7
HOGENOMQ6KCM7
Homologs : HomoloGeneSLC25A25
Homology/Alignments : Family Browser (UCSC)SLC25A25
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSLC25A25 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SLC25A25
dbVarSLC25A25
ClinVarSLC25A25
1000_GenomesSLC25A25 
Exome Variant ServerSLC25A25
ExAC (Exome Aggregation Consortium)SLC25A25 (select the gene name)
Genetic variants : HAPMAP114789
Genomic Variants (DGV)SLC25A25 [DGVbeta]
DECIPHERSLC25A25 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSLC25A25 
Mutations
ICGC Data PortalSLC25A25 
TCGA Data PortalSLC25A25 
Broad Tumor PortalSLC25A25
OASIS PortalSLC25A25 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSLC25A25  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSLC25A25
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch SLC25A25
DgiDB (Drug Gene Interaction Database)SLC25A25
DoCM (Curated mutations)SLC25A25 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SLC25A25 (select a term)
intoGenSLC25A25
Cancer3DSLC25A25(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608745   
Orphanet
MedgenSLC25A25
Genetic Testing Registry SLC25A25
NextProtQ6KCM7 [Medical]
TSGene114789
GENETestsSLC25A25
Target ValidationSLC25A25
Huge Navigator SLC25A25 [HugePedia]
snp3D : Map Gene to Disease114789
BioCentury BCIQSLC25A25
ClinGenSLC25A25
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD114789
Chemical/Pharm GKB GenePA134952319
Clinical trialSLC25A25
Miscellaneous
canSAR (ICR)SLC25A25 (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSLC25A25
EVEXSLC25A25
GoPubMedSLC25A25
iHOPSLC25A25
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:38:02 CEST 2017

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