SLC25A26 (solute carrier family 25 member 26)

2014-08-01  

Identity

HGNC
LOCATION
3p14.1
LOCUSID
ALIAS
COXPD28,SAMC
FUSION GENES

Other Information

Locus ID:

NCBI: 115286
MIM: 611037
HGNC: 20661
Ensembl: ENSG00000144741

Variants:

dbSNP: 115286
ClinVar: 115286
TCGA: ENSG00000144741
COSMIC: SLC25A26

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000144741ENST00000336733Q70HW3
ENSG00000144741ENST00000354883Q70HW3
ENSG00000144741ENST00000413054H7C430
ENSG00000144741ENST00000464350H0YCZ5
ENSG00000144741ENST00000483224H0YF50

Expression (GTEx)

0
5
10
15

Pathways

PathwaySourceExternal ID
Transmembrane transport of small moleculesREACTOMER-HSA-382551
SLC-mediated transmembrane transportREACTOMER-HSA-425407
Transport of inorganic cations/anions and amino acids/oligopeptidesREACTOMER-HSA-425393

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
232661872013The mitochondrial transporter family SLC25: identification, properties and physiopathology.159
146748842004Identification of the human mitochondrial S-adenosylmethionine transporter: bacterial expression, reconstitution, functional characterization and tissue distribution.42
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.17
265224692015Intra-mitochondrial Methylation Deficiency Due to Mutations in SLC25A26.11
281185292017SLC25A26 overexpression impairs cell function via mtDNA hypermethylation and rewiring of methyl metabolism.5

Citation

Dessen P

SLC25A26 (solute carrier family 25 member 26)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54628/slc25a26