Atlas of Genetics and Cytogenetics in Oncology and Haematology

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SLC25A27 (solute carrier family 25 member 27)

Identity

Alias (NCBI)UCP4
HGNC (Hugo) SLC25A27
HGNC Alias symbUCP4
FLJ33552
HGNC Previous namesolute carrier family 25, member 27
LocusID (NCBI) 9481
Atlas_Id 52475
Location 6p12.3  [Link to chromosome band 6p12]
Location_base_pair Starts at 46652975 and ends at 46678190 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)SLC25A27   21065
Cards
Entrez_Gene (NCBI)SLC25A27  9481  solute carrier family 25 member 27
AliasesUCP4
GeneCards (Weizmann)SLC25A27
Ensembl hg19 (Hinxton)ENSG00000153291 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000153291 [Gene_View]  ENSG00000153291 [Sequence]  chr6:46652975-46678190 [Contig_View]  SLC25A27 [Vega]
ICGC DataPortalENSG00000153291
TCGA cBioPortalSLC25A27
AceView (NCBI)SLC25A27
Genatlas (Paris)SLC25A27
WikiGenes9481
SOURCE (Princeton)SLC25A27
Genetics Home Reference (NIH)SLC25A27
Genomic and cartography
GoldenPath hg38 (UCSC)SLC25A27  -     chr6:46652975-46678190 +  6p12.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SLC25A27  -     6p12.3   [Description]    (hg19-Feb_2009)
GoldenPathSLC25A27 - 6p12.3 [CytoView hg19]  SLC25A27 - 6p12.3 [CytoView hg38]
ImmunoBaseENSG00000153291
genome Data Viewer NCBISLC25A27 [Mapview hg19]  
OMIM613725   
Gene and transcription
Genbank (Entrez)AF110532 AK090871 AK291427 AK295233 AK302906
RefSeq transcript (Entrez)NM_001204051 NM_001204052 NM_004277
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SLC25A27
Alternative Splicing GalleryENSG00000153291
Gene ExpressionSLC25A27 [ NCBI-GEO ]   SLC25A27 [ EBI - ARRAY_EXPRESS ]   SLC25A27 [ SEEK ]   SLC25A27 [ MEM ]
Gene Expression Viewer (FireBrowse)SLC25A27 [ Firebrowse - Broad ]
GenevisibleExpression of SLC25A27 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9481
GTEX Portal (Tissue expression)SLC25A27
Human Protein AtlasENSG00000153291-SLC25A27 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO95847   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO95847  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO95847
Splice isoforms : SwissVarO95847
PhosPhoSitePlusO95847
Domaine pattern : Prosite (Expaxy)SOLCAR (PS50920)   
Domains : Interpro (EBI)Mitochondrial_sb/sol_carrier    Mt_carrier_dom_sf   
Domain families : Pfam (Sanger)Mito_carr (PF00153)   
Domain families : Pfam (NCBI)pfam00153   
Conserved Domain (NCBI)SLC25A27
DMDM Disease mutations9481
Blocks (Seattle)SLC25A27
SuperfamilyO95847
Human Protein Atlas [tissue]ENSG00000153291-SLC25A27 [tissue]
Peptide AtlasO95847
HPRD15358
IPIIPI00383871   IPI00909650   IPI00640299   IPI00925337   IPI00980641   IPI00640903   IPI00644996   
Protein Interaction databases
DIP (DOE-UCLA)O95847
IntAct (EBI)O95847
FunCoupENSG00000153291
BioGRIDSLC25A27
STRING (EMBL)SLC25A27
ZODIACSLC25A27
Ontologies - Pathways
QuickGOO95847
Ontology : AmiGOmitochondrion  mitochondrial inner membrane  positive regulation of cell proliferation  response to cold  negative regulation of mitochondrial membrane potential  integral component of membrane  mitochondrial membrane  cellular triglyceride homeostasis  neuronal cell body  negative regulation of apoptotic process  apical part of cell  regulation of glucose import  inner ear development  negative regulation of mitochondrial calcium ion concentration  neuron death  proton transmembrane transport  
Ontology : EGO-EBImitochondrion  mitochondrial inner membrane  positive regulation of cell proliferation  response to cold  negative regulation of mitochondrial membrane potential  integral component of membrane  mitochondrial membrane  cellular triglyceride homeostasis  neuronal cell body  negative regulation of apoptotic process  apical part of cell  regulation of glucose import  inner ear development  negative regulation of mitochondrial calcium ion concentration  neuron death  proton transmembrane transport  
NDEx NetworkSLC25A27
Atlas of Cancer Signalling NetworkSLC25A27
Wikipedia pathwaysSLC25A27
Orthology - Evolution
OrthoDB9481
GeneTree (enSembl)ENSG00000153291
Phylogenetic Trees/Animal Genes : TreeFamSLC25A27
HOGENOMO95847
Homologs : HomoloGeneSLC25A27
Homology/Alignments : Family Browser (UCSC)SLC25A27
Gene fusions - Rearrangements
Fusion : QuiverSLC25A27
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSLC25A27 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SLC25A27
dbVarSLC25A27
ClinVarSLC25A27
MonarchSLC25A27
1000_GenomesSLC25A27 
Exome Variant ServerSLC25A27
GNOMAD BrowserENSG00000153291
Varsome BrowserSLC25A27
Genetic variants : HAPMAP9481
Genomic Variants (DGV)SLC25A27 [DGVbeta]
DECIPHERSLC25A27 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSLC25A27 
Mutations
ICGC Data PortalSLC25A27 
TCGA Data PortalSLC25A27 
Broad Tumor PortalSLC25A27
OASIS PortalSLC25A27 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSLC25A27  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DSLC25A27
Mutations and Diseases : HGMDSLC25A27
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch SLC25A27
DgiDB (Drug Gene Interaction Database)SLC25A27
DoCM (Curated mutations)SLC25A27 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SLC25A27 (select a term)
intoGenSLC25A27
Cancer3DSLC25A27(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613725   
Orphanet
DisGeNETSLC25A27
MedgenSLC25A27
Genetic Testing Registry SLC25A27
NextProtO95847 [Medical]
TSGene9481
GENETestsSLC25A27
Target ValidationSLC25A27
Huge Navigator SLC25A27 [HugePedia]
snp3D : Map Gene to Disease9481
BioCentury BCIQSLC25A27
ClinGenSLC25A27
Clinical trials, drugs, therapy
Protein Interactions : CTD9481
Pharm GKB GenePA134970102
Clinical trialSLC25A27
Miscellaneous
canSAR (ICR)SLC25A27 (select the gene name)
HarmonizomeSLC25A27
DataMed IndexSLC25A27
Probes
Litterature
PubMed36 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSLC25A27
EVEXSLC25A27
GoPubMedSLC25A27
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 14 14:32:49 CEST 2020
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