Atlas of Genetics and Cytogenetics in Oncology and Haematology


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SLC25A3 (solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3)

Identity

Alias_namesPHC
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
Other aliasOK/SW-cl.48
PTP
HGNC (Hugo) SLC25A3
LocusID (NCBI) 5250
Atlas_Id 73351
Location 12q23.1  [Link to chromosome band 12q23]
Location_base_pair Starts at 98987403 and ends at 98995778 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
NDRG1 (8q24.22) / SLC25A3 (12q23.1)NPEPPS (17q21.32) / SLC25A3 (12q23.1)SLC25A3 (12q23.1) / CDC42BPB (14q32.32)
SLC25A3 (12q23.1) / DDX27 (20q13.13)SLC25A3 (12q23.1) / FAM111A (11q12.1)SLC25A3 (12q23.1) / LAMB1 (7q31.1)
SLC25A3 (12q23.1) / LBR (1q42.12)SLC25A3 (12q23.1) / SIAE (11q24.2)SLC25A3 (12q23.1) / SLC12A7 (5p15.33)
SLC25A3 (12q23.1) / SLC25A3 (12q23.1)SLC25A3 (12q23.1) / TSNAX (1q42.2)SLC25A3 (12q23.1) / UBE2QL1 (5p15.31)
SMG1 (16p12.3) / SLC25A3 (12q23.1)TSNAX (1q42.2) / SLC25A3 (12q23.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SLC25A3   10989
Cards
Entrez_Gene (NCBI)SLC25A3  5250  solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
AliasesOK/SW-cl.48; PHC; PTP
GeneCards (Weizmann)SLC25A3
Ensembl hg19 (Hinxton)ENSG00000075415 [Gene_View]  chr12:98987403-98995778 [Contig_View]  SLC25A3 [Vega]
Ensembl hg38 (Hinxton)ENSG00000075415 [Gene_View]  chr12:98987403-98995778 [Contig_View]  SLC25A3 [Vega]
ICGC DataPortalENSG00000075415
TCGA cBioPortalSLC25A3
AceView (NCBI)SLC25A3
Genatlas (Paris)SLC25A3
WikiGenes5250
SOURCE (Princeton)SLC25A3
Genetics Home Reference (NIH)SLC25A3
Genomic and cartography
GoldenPath hg19 (UCSC)SLC25A3  -     chr12:98987403-98995778 +  12q23.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)SLC25A3  -     12q23.1   [Description]    (hg38-Dec_2013)
EnsemblSLC25A3 - 12q23.1 [CytoView hg19]  SLC25A3 - 12q23.1 [CytoView hg38]
Mapping of homologs : NCBISLC25A3 [Mapview hg19]  SLC25A3 [Mapview hg38]
OMIM600370   610773   
Gene and transcription
Genbank (Entrez)AB064666 AK057575 AK074759 AK092689 AK222658
RefSeq transcript (Entrez)NM_002635 NM_005888 NM_213611 NM_213612
RefSeq genomic (Entrez)NC_000012 NC_018923 NG_011702 NT_029419 NW_004929384
Consensus coding sequences : CCDS (NCBI)SLC25A3
Cluster EST : UnigeneHs.290404 [ NCBI ]
CGAP (NCI)Hs.290404
Alternative Splicing GalleryENSG00000075415
Gene ExpressionSLC25A3 [ NCBI-GEO ]   SLC25A3 [ EBI - ARRAY_EXPRESS ]   SLC25A3 [ SEEK ]   SLC25A3 [ MEM ]
Gene Expression Viewer (FireBrowse)SLC25A3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5250
GTEX Portal (Tissue expression)SLC25A3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ00325   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ00325  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ00325
Splice isoforms : SwissVarQ00325
PhosPhoSitePlusQ00325
Domaine pattern : Prosite (Expaxy)SOLCAR (PS50920)   
Domains : Interpro (EBI)Mitochondrial_sb/sol_carrier    Mt_carrier_dom   
Domain families : Pfam (Sanger)Mito_carr (PF00153)   
Domain families : Pfam (NCBI)pfam00153   
Conserved Domain (NCBI)SLC25A3
DMDM Disease mutations5250
Blocks (Seattle)SLC25A3
SuperfamilyQ00325
Human Protein AtlasENSG00000075415
Peptide AtlasQ00325
HPRD02654
IPIIPI00022202   IPI00215777   IPI01022384   IPI01022627   IPI01022494   IPI01022950   IPI01021838   IPI01021698   
Protein Interaction databases
DIP (DOE-UCLA)Q00325
IntAct (EBI)Q00325
FunCoupENSG00000075415
BioGRIDSLC25A3
STRING (EMBL)SLC25A3
ZODIACSLC25A3
Ontologies - Pathways
QuickGOQ00325
Ontology : AmiGOmitochondrion  mitochondrial inner membrane  integral component of plasma membrane  generation of precursor metabolites and energy  transport  symporter activity  phosphate ion carrier activity  membrane  protein complex binding  phosphate ion transmembrane transport  extracellular exosome  
Ontology : EGO-EBImitochondrion  mitochondrial inner membrane  integral component of plasma membrane  generation of precursor metabolites and energy  transport  symporter activity  phosphate ion carrier activity  membrane  protein complex binding  phosphate ion transmembrane transport  extracellular exosome  
NDEx NetworkSLC25A3
Atlas of Cancer Signalling NetworkSLC25A3
Wikipedia pathwaysSLC25A3
Orthology - Evolution
OrthoDB5250
GeneTree (enSembl)ENSG00000075415
Phylogenetic Trees/Animal Genes : TreeFamSLC25A3
HOVERGENQ00325
HOGENOMQ00325
Homologs : HomoloGeneSLC25A3
Homology/Alignments : Family Browser (UCSC)SLC25A3
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSLC25A3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SLC25A3
dbVarSLC25A3
ClinVarSLC25A3
1000_GenomesSLC25A3 
Exome Variant ServerSLC25A3
ExAC (Exome Aggregation Consortium)SLC25A3 (select the gene name)
Genetic variants : HAPMAP5250
Genomic Variants (DGV)SLC25A3 [DGVbeta]
DECIPHER (Syndromes)12:98987403-98995778  ENSG00000075415
CONAN: Copy Number AnalysisSLC25A3 
Mutations
ICGC Data PortalSLC25A3 
TCGA Data PortalSLC25A3 
Broad Tumor PortalSLC25A3
OASIS PortalSLC25A3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSLC25A3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSLC25A3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch SLC25A3
DgiDB (Drug Gene Interaction Database)SLC25A3
DoCM (Curated mutations)SLC25A3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SLC25A3 (select a term)
intoGenSLC25A3
Cancer3DSLC25A3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600370    610773   
Orphanet12107   
MedgenSLC25A3
Genetic Testing Registry SLC25A3
NextProtQ00325 [Medical]
TSGene5250
GENETestsSLC25A3
Huge Navigator SLC25A3 [HugePedia]
snp3D : Map Gene to Disease5250
BioCentury BCIQSLC25A3
ClinGenSLC25A3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5250
Chemical/Pharm GKB GenePA35865
Clinical trialSLC25A3
Miscellaneous
canSAR (ICR)SLC25A3 (select the gene name)
Probes
Litterature
PubMed66 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSLC25A3
EVEXSLC25A3
GoPubMedSLC25A3
iHOPSLC25A3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:43:31 CET 2017

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