SLC25A4 (solute carrier family 25 member 4)

2003-05-01  

Identity

HGNC
LOCATION
4q35.1
LOCUSID
ALIAS
AAC1,ANT,ANT
FUSION GENES

Other Information

Locus ID:

NCBI: 291
MIM: 103220
HGNC: 10990
Ensembl: ENSG00000151729

Variants:

dbSNP: 291
ClinVar: 291
TCGA: ENSG00000151729
COSMIC: SLC25A4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000151729ENST00000281456P12235
ENSG00000151729ENST00000281456A0A0S2Z3H3
ENSG00000151729ENST00000491736V9GYG0

Expression (GTEx)

0
100
200
300
400
500
600

Pathways

PathwaySourceExternal ID
Calcium signaling pathwayKEGGko04020
Huntington's diseaseKEGGko05016
Calcium signaling pathwayKEGGhsa04020
Parkinson's diseaseKEGGhsa05012
Huntington's diseaseKEGGhsa05016
HTLV-I infectionKEGGko05166
HTLV-I infectionKEGGhsa05166
cGMP-PKG signaling pathwayKEGGhsa04022
cGMP-PKG signaling pathwayKEGGko04022
Metabolism of proteinsREACTOMER-HSA-392499
Mitochondrial protein importREACTOMER-HSA-1268020
DiseaseREACTOMER-HSA-1643685
Infectious diseaseREACTOMER-HSA-5663205
HIV InfectionREACTOMER-HSA-162906
Host Interactions of HIV factorsREACTOMER-HSA-162909
Interactions of Vpr with host cellular proteinsREACTOMER-HSA-176033
Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilizationREACTOMER-HSA-180897
MetabolismREACTOMER-HSA-1430728
Integration of energy metabolismREACTOMER-HSA-163685
Regulation of insulin secretionREACTOMER-HSA-422356

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
372781582023Human mitochondrial ADP/ATP carrier SLC25A4 operates with a ping-pong kinetic mechanism.4
374871372023Loss of ANT1 Increases Fibrosis and Epithelial Cell Senescence in Idiopathic Pulmonary Fibrosis.4
372781582023Human mitochondrial ADP/ATP carrier SLC25A4 operates with a ping-pong kinetic mechanism.4
374871372023Loss of ANT1 Increases Fibrosis and Epithelial Cell Senescence in Idiopathic Pulmonary Fibrosis.4
360306282022ANT1 overexpression models: Some similarities with facioscapulohumeral muscular dystrophy.4
360306282022ANT1 overexpression models: Some similarities with facioscapulohumeral muscular dystrophy.4
343329522021Site-specific acetylation of adenine nucleotide translocase 1 at lysine 23 in human muscle.2
347554702021Conformational change of adenine nucleotide translocase-1 mediates cisplatin resistance induced by EBV-LMP1.8
343329522021Site-specific acetylation of adenine nucleotide translocase 1 at lysine 23 in human muscle.2
347554702021Conformational change of adenine nucleotide translocase-1 mediates cisplatin resistance induced by EBV-LMP1.8
323761552020The relationship between ANT1 and NFL with autophagy and mitophagy markers in patients with multiple sclerosis.9
328908922020Evaluation of the Diagnostic and Predictive Value of Serum Levels of ANT1, ATG5, and Parkin in Multiple Sclerosis.8
333966582020Differential Expression of ADP/ATP Carriers as a Biomarker of Metabolic Remodeling and Survival in Kidney Cancers.7
323761552020The relationship between ANT1 and NFL with autophagy and mitophagy markers in patients with multiple sclerosis.9
328908922020Evaluation of the Diagnostic and Predictive Value of Serum Levels of ANT1, ATG5, and Parkin in Multiple Sclerosis.8

Citation

Dessen P

SLC25A4 (solute carrier family 25 member 4)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/42317/slc25a4