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SLC25A5 (solute carrier family 25 member 5)

Identity

Alias (NCBI)2F1
AAC2
ANT2
T2
T3
HGNC (Hugo) SLC25A5
HGNC Alias symbT2
2F1
T3
HGNC Previous nameANT2
HGNC Previous namesolute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
LocusID (NCBI) 292
Atlas_Id 46455
Location Xq24  [Link to chromosome band Xq24]
Location_base_pair Starts at 119468444 and ends at 119471396 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
PDIA5 (3q21.1) / SLC25A5 (Xq24)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)SLC25A5   10991
Cards
Entrez_Gene (NCBI)SLC25A5    solute carrier family 25 member 5
Aliases2F1; AAC2; ANT2; T2; 
T3
GeneCards (Weizmann)SLC25A5
Ensembl hg19 (Hinxton)ENSG00000005022 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000005022 [Gene_View]  ENSG00000005022 [Sequence]  chrX:119468444-119471396 [Contig_View]  SLC25A5 [Vega]
ICGC DataPortalENSG00000005022
TCGA cBioPortalSLC25A5
AceView (NCBI)SLC25A5
Genatlas (Paris)SLC25A5
SOURCE (Princeton)SLC25A5
Genetics Home Reference (NIH)SLC25A5
Genomic and cartography
GoldenPath hg38 (UCSC)SLC25A5  -     chrX:119468444-119471396 +  Xq24   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SLC25A5  -     Xq24   [Description]    (hg19-Feb_2009)
GoldenPathSLC25A5 - Xq24 [CytoView hg19]  SLC25A5 - Xq24 [CytoView hg38]
ImmunoBaseENSG00000005022
Genome Data Viewer NCBISLC25A5 [Mapview hg19]  
OMIM300150   
Gene and transcription
Genbank (Entrez)AK315292 BC056160 BC068199 BQ223988 DB555059
RefSeq transcript (Entrez)NM_001152
Consensus coding sequences : CCDS (NCBI)SLC25A5
Gene ExpressionSLC25A5 [ NCBI-GEO ]   SLC25A5 [ EBI - ARRAY_EXPRESS ]   SLC25A5 [ SEEK ]   SLC25A5 [ MEM ]
Gene Expression Viewer (FireBrowse)SLC25A5 [ Firebrowse - Broad ]
GenevisibleExpression of SLC25A5 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)292
GTEX Portal (Tissue expression)SLC25A5
Human Protein AtlasENSG00000005022-SLC25A5 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP05141   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP05141  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP05141
PhosPhoSitePlusP05141
Domaine pattern : Prosite (Expaxy)SOLCAR (PS50920)   
Domains : Interpro (EBI)ADT_euk_type    Mit_carrier    Mitochondrial_sb/sol_carrier    Mt_carrier_dom_sf   
Domain families : Pfam (Sanger)Mito_carr (PF00153)   
Domain families : Pfam (NCBI)pfam00153   
Conserved Domain (NCBI)SLC25A5
SuperfamilyP05141
AlphaFold pdb e-kbP05141   
Human Protein Atlas [tissue]ENSG00000005022-SLC25A5 [tissue]
HPRD02147
Protein Interaction databases
DIP (DOE-UCLA)P05141
IntAct (EBI)P05141
BioGRIDSLC25A5
STRING (EMBL)SLC25A5
ZODIACSLC25A5
Ontologies - Pathways
QuickGOP05141
Ontology : AmiGOadenine nucleotide transmembrane transporter activity  RNA binding  ATP:ADP antiporter activity  protein binding  nucleus  mitochondrion  mitochondrion  mitochondrial inner membrane  mitochondrial permeability transition pore complex  integral component of plasma membrane  chromosome segregation  positive regulation of cell population proliferation  proton transmembrane transporter activity  adenine transmembrane transporter activity  adenine transport  membrane  membrane  oxidative phosphorylation uncoupler activity  B cell differentiation  erythrocyte differentiation  ubiquitin protein ligase binding  mitochondrial nucleoid  membrane raft  regulation of mitochondrial membrane permeability  adenine nucleotide transport  MMXD complex  mitochondrial ADP transmembrane transport  negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway  positive regulation of mitophagy  proton transmembrane transport  mitochondrial ATP transmembrane transport  cellular response to leukemia inhibitory factor  adaptive thermogenesis  
Ontology : EGO-EBIadenine nucleotide transmembrane transporter activity  RNA binding  ATP:ADP antiporter activity  protein binding  nucleus  mitochondrion  mitochondrion  mitochondrial inner membrane  mitochondrial permeability transition pore complex  integral component of plasma membrane  chromosome segregation  positive regulation of cell population proliferation  proton transmembrane transporter activity  adenine transmembrane transporter activity  adenine transport  membrane  membrane  oxidative phosphorylation uncoupler activity  B cell differentiation  erythrocyte differentiation  ubiquitin protein ligase binding  mitochondrial nucleoid  membrane raft  regulation of mitochondrial membrane permeability  adenine nucleotide transport  MMXD complex  mitochondrial ADP transmembrane transport  negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway  positive regulation of mitophagy  proton transmembrane transport  mitochondrial ATP transmembrane transport  cellular response to leukemia inhibitory factor  adaptive thermogenesis  
Pathways : KEGGCalcium signaling pathway    Parkinson's disease    Huntington's disease    HTLV-I infection   
NDEx NetworkSLC25A5
Atlas of Cancer Signalling NetworkSLC25A5
Wikipedia pathwaysSLC25A5
Orthology - Evolution
OrthoDB292
GeneTree (enSembl)ENSG00000005022
Phylogenetic Trees/Animal Genes : TreeFamSLC25A5
Homologs : HomoloGeneSLC25A5
Homology/Alignments : Family Browser (UCSC)SLC25A5
Gene fusions - Rearrangements
Fusion : QuiverSLC25A5
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSLC25A5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SLC25A5
dbVarSLC25A5
ClinVarSLC25A5
MonarchSLC25A5
1000_GenomesSLC25A5 
Exome Variant ServerSLC25A5
GNOMAD BrowserENSG00000005022
Varsome BrowserSLC25A5
ACMGSLC25A5 variants
VarityP05141
Genomic Variants (DGV)SLC25A5 [DGVbeta]
DECIPHERSLC25A5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSLC25A5 
Mutations
ICGC Data PortalSLC25A5 
TCGA Data PortalSLC25A5 
Broad Tumor PortalSLC25A5
OASIS PortalSLC25A5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSLC25A5  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DSLC25A5
Mutations and Diseases : HGMDSLC25A5
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaSLC25A5
DgiDB (Drug Gene Interaction Database)SLC25A5
DoCM (Curated mutations)SLC25A5
CIViC (Clinical Interpretations of Variants in Cancer)SLC25A5
Cancer3DSLC25A5
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300150   
Orphanet
DisGeNETSLC25A5
MedgenSLC25A5
Genetic Testing Registry SLC25A5
NextProtP05141 [Medical]
GENETestsSLC25A5
Target ValidationSLC25A5
Huge Navigator SLC25A5 [HugePedia]
ClinGenSLC25A5
Clinical trials, drugs, therapy
MyCancerGenomeSLC25A5
Protein Interactions : CTDSLC25A5
Pharm GKB GenePA35867
PharosP05141
Clinical trialSLC25A5
Miscellaneous
canSAR (ICR)SLC25A5
HarmonizomeSLC25A5
DataMed IndexSLC25A5
Probes
Litterature
PubMed208 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXSLC25A5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:31:35 CEST 2021

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