Atlas of Genetics and Cytogenetics in Oncology and Haematology

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SLC25A5 (solute carrier family 25 member 5)

Identity

Alias_namesANT2
solute carrier family 25 (mitochondrial carrier
Alias_symbol (synonym)T2
2F1
T3
Other aliasAAC2
HGNC (Hugo) SLC25A5
LocusID (NCBI) 292
Atlas_Id 46455
Location Xq24  [Link to chromosome band Xq24]
Location_base_pair Starts at 119468400 and ends at 119471396 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
PDIA5 (3q21.1) / SLC25A5 (Xq24)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)SLC25A5   10991
Cards
Entrez_Gene (NCBI)SLC25A5  292  solute carrier family 25 member 5
Aliases2F1; AAC2; ANT2; T2; 
T3
GeneCards (Weizmann)SLC25A5
Ensembl hg19 (Hinxton)ENSG00000005022 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000005022 [Gene_View]  ENSG00000005022 [Sequence]  chrX:119468400-119471396 [Contig_View]  SLC25A5 [Vega]
ICGC DataPortalENSG00000005022
TCGA cBioPortalSLC25A5
AceView (NCBI)SLC25A5
Genatlas (Paris)SLC25A5
WikiGenes292
SOURCE (Princeton)SLC25A5
Genetics Home Reference (NIH)SLC25A5
Genomic and cartography
GoldenPath hg38 (UCSC)SLC25A5  -     chrX:119468400-119471396 +  Xq24   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SLC25A5  -     Xq24   [Description]    (hg19-Feb_2009)
EnsemblSLC25A5 - Xq24 [CytoView hg19]  SLC25A5 - Xq24 [CytoView hg38]
Mapping of homologs : NCBISLC25A5 [Mapview hg19]  SLC25A5 [Mapview hg38]
OMIM300150   
Gene and transcription
Genbank (Entrez)AK315292 BC056160 BC068199 BQ223988 DB555059
RefSeq transcript (Entrez)NM_001152
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SLC25A5
Cluster EST : UnigeneHs.632282 [ NCBI ]
CGAP (NCI)Hs.632282
Alternative Splicing GalleryENSG00000005022
Gene ExpressionSLC25A5 [ NCBI-GEO ]   SLC25A5 [ EBI - ARRAY_EXPRESS ]   SLC25A5 [ SEEK ]   SLC25A5 [ MEM ]
Gene Expression Viewer (FireBrowse)SLC25A5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)292
GTEX Portal (Tissue expression)SLC25A5
Human Protein AtlasENSG00000005022-SLC25A5 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP05141   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP05141  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP05141
Splice isoforms : SwissVarP05141
PhosPhoSitePlusP05141
Domaine pattern : Prosite (Expaxy)SOLCAR (PS50920)   
Domains : Interpro (EBI)Aden_trnslctor    Mit_carrier    Mitochondrial_sb/sol_carrier    Mt_carrier_dom_sf   
Domain families : Pfam (Sanger)Mito_carr (PF00153)   
Domain families : Pfam (NCBI)pfam00153   
Conserved Domain (NCBI)SLC25A5
DMDM Disease mutations292
Blocks (Seattle)SLC25A5
SuperfamilyP05141
Human Protein Atlas [tissue]ENSG00000005022-SLC25A5 [tissue]
Peptide AtlasP05141
HPRD02147
IPIIPI00007188   
Protein Interaction databases
DIP (DOE-UCLA)P05141
IntAct (EBI)P05141
FunCoupENSG00000005022
BioGRIDSLC25A5
STRING (EMBL)SLC25A5
ZODIACSLC25A5
Ontologies - Pathways
QuickGOP05141
Ontology : AmiGORNA binding  ATP:ADP antiporter activity  protein binding  nucleus  mitochondrion  mitochondrion  mitochondrial inner membrane  integral component of plasma membrane  chromosome segregation  positive regulation of cell proliferation  adenine transmembrane transporter activity  adenine transport  ADP transport  ATP transport  membrane  viral process  ubiquitin protein ligase binding  mitochondrial nucleoid  myelin sheath  membrane raft  regulation of mitochondrial membrane permeability  regulation of insulin secretion  transmembrane transport  MMXD complex  negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway  cellular response to leukemia inhibitory factor  
Ontology : EGO-EBIRNA binding  ATP:ADP antiporter activity  protein binding  nucleus  mitochondrion  mitochondrion  mitochondrial inner membrane  integral component of plasma membrane  chromosome segregation  positive regulation of cell proliferation  adenine transmembrane transporter activity  adenine transport  ADP transport  ATP transport  membrane  viral process  ubiquitin protein ligase binding  mitochondrial nucleoid  myelin sheath  membrane raft  regulation of mitochondrial membrane permeability  regulation of insulin secretion  transmembrane transport  MMXD complex  negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway  cellular response to leukemia inhibitory factor  
Pathways : KEGGCalcium signaling pathway    Parkinson's disease    Huntington's disease    HTLV-I infection   
NDEx NetworkSLC25A5
Atlas of Cancer Signalling NetworkSLC25A5
Wikipedia pathwaysSLC25A5
Orthology - Evolution
OrthoDB292
GeneTree (enSembl)ENSG00000005022
Phylogenetic Trees/Animal Genes : TreeFamSLC25A5
HOVERGENP05141
HOGENOMP05141
Homologs : HomoloGeneSLC25A5
Homology/Alignments : Family Browser (UCSC)SLC25A5
Gene fusions - Rearrangements
Fusion : QuiverSLC25A5
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSLC25A5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SLC25A5
dbVarSLC25A5
ClinVarSLC25A5
1000_GenomesSLC25A5 
Exome Variant ServerSLC25A5
ExAC (Exome Aggregation Consortium)ENSG00000005022
GNOMAD BrowserENSG00000005022
Varsome BrowserSLC25A5
Genetic variants : HAPMAP292
Genomic Variants (DGV)SLC25A5 [DGVbeta]
DECIPHERSLC25A5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSLC25A5 
Mutations
ICGC Data PortalSLC25A5 
TCGA Data PortalSLC25A5 
Broad Tumor PortalSLC25A5
OASIS PortalSLC25A5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSLC25A5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSLC25A5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)X-chromosome gene database
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch SLC25A5
DgiDB (Drug Gene Interaction Database)SLC25A5
DoCM (Curated mutations)SLC25A5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SLC25A5 (select a term)
intoGenSLC25A5
Cancer3DSLC25A5(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300150   
Orphanet
DisGeNETSLC25A5
MedgenSLC25A5
Genetic Testing Registry SLC25A5
NextProtP05141 [Medical]
TSGene292
GENETestsSLC25A5
Target ValidationSLC25A5
Huge Navigator SLC25A5 [HugePedia]
snp3D : Map Gene to Disease292
BioCentury BCIQSLC25A5
ClinGenSLC25A5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD292
Chemical/Pharm GKB GenePA35867
Clinical trialSLC25A5
Miscellaneous
canSAR (ICR)SLC25A5 (select the gene name)
Probes
Litterature
PubMed118 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSLC25A5
EVEXSLC25A5
GoPubMedSLC25A5
iHOPSLC25A5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Aug 27 11:52:47 CEST 2018
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