Atlas of Genetics and Cytogenetics in Oncology and Haematology


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SLC26A6 (solute carrier family 26 member 6)

Identity

Alias_namessolute carrier family 26, member 6
solute carrier family 26 (anion exchanger), member 6
Alias_symbol (synonym)DKFZp586E1422
Other alias-
HGNC (Hugo) SLC26A6
LocusID (NCBI) 65010
Atlas_Id 53046
Location 3p21.31  [Link to chromosome band 3p21]
Location_base_pair Starts at 48625723 and ends at 48633846 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
SLC26A6 (3p21.31) / PRKAR2A (3p21.31)SLC26A6 3p21.31 PRKAR2A

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SLC26A6   14472
Cards
Entrez_Gene (NCBI)SLC26A6  65010  solute carrier family 26 member 6
Aliases
GeneCards (Weizmann)SLC26A6
Ensembl hg19 (Hinxton)ENSG00000225697 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000225697 [Gene_View]  chr3:48625723-48633846 [Contig_View]  SLC26A6 [Vega]
ICGC DataPortalENSG00000225697
TCGA cBioPortalSLC26A6
AceView (NCBI)SLC26A6
Genatlas (Paris)SLC26A6
WikiGenes65010
SOURCE (Princeton)SLC26A6
Genetics Home Reference (NIH)SLC26A6
Genomic and cartography
GoldenPath hg38 (UCSC)SLC26A6  -     chr3:48625723-48633846 -  3p21.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SLC26A6  -     3p21.31   [Description]    (hg19-Feb_2009)
EnsemblSLC26A6 - 3p21.31 [CytoView hg19]  SLC26A6 - 3p21.31 [CytoView hg38]
Mapping of homologs : NCBISLC26A6 [Mapview hg19]  SLC26A6 [Mapview hg38]
OMIM610068   
Gene and transcription
Genbank (Entrez)AB033288 AB102713 AB208936 AF161369 AF279265
RefSeq transcript (Entrez)NM_001040454 NM_001281732 NM_001281733 NM_022911 NM_134263 NM_134426
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SLC26A6
Cluster EST : UnigeneHs.663208 [ NCBI ]
CGAP (NCI)Hs.663208
Alternative Splicing GalleryENSG00000225697
Gene ExpressionSLC26A6 [ NCBI-GEO ]   SLC26A6 [ EBI - ARRAY_EXPRESS ]   SLC26A6 [ SEEK ]   SLC26A6 [ MEM ]
Gene Expression Viewer (FireBrowse)SLC26A6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)65010
GTEX Portal (Tissue expression)SLC26A6
Human Protein AtlasENSG00000225697-SLC26A6 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BXS9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BXS9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BXS9
Splice isoforms : SwissVarQ9BXS9
PhosPhoSitePlusQ9BXS9
Domaine pattern : Prosite (Expaxy)SLC26A (PS01130)    STAS (PS50801)   
Domains : Interpro (EBI)S04_transporter_CS    SLC26A/SulP_dom    SLC26A/SulP_fam    SLC26A6    STAS_dom   
Domain families : Pfam (Sanger)STAS (PF01740)    Sulfate_transp (PF00916)   
Domain families : Pfam (NCBI)pfam01740    pfam00916   
Conserved Domain (NCBI)SLC26A6
DMDM Disease mutations65010
Blocks (Seattle)SLC26A6
SuperfamilyQ9BXS9
Human Protein Atlas [tissue]ENSG00000225697-SLC26A6 [tissue]
Peptide AtlasQ9BXS9
HPRD10235
IPIIPI00107312   IPI00218923   IPI00748085   IPI00555604   IPI00796123   IPI00816666   IPI00549961   IPI00796771   IPI00925187   IPI00910320   IPI00925166   IPI00924934   IPI00924682   IPI00924454   IPI00927737   IPI00927484   
Protein Interaction databases
DIP (DOE-UCLA)Q9BXS9
IntAct (EBI)Q9BXS9
FunCoupENSG00000225697
BioGRIDSLC26A6
STRING (EMBL)SLC26A6
ZODIACSLC26A6
Ontologies - Pathways
QuickGOQ9BXS9
Ontology : AmiGOchloride channel activity  inorganic anion exchanger activity  endoplasmic reticulum  plasma membrane  integral component of plasma membrane  ion transport  chloride transport  secondary active sulfate transmembrane transporter activity  sulfate transport  sulfate transport  vesicle membrane  bicarbonate transmembrane transporter activity  bicarbonate transmembrane transporter activity  chloride transmembrane transporter activity  chloride transmembrane transporter activity  sulfate transmembrane transporter activity  anion:anion antiporter activity  anion:anion antiporter activity  formate transmembrane transporter activity  efflux transmembrane transporter activity  formate uptake transmembrane transporter activity  formate efflux transmembrane transporter activity  bicarbonate transport  formate transport  mannitol transport  membrane  integral component of membrane  basolateral plasma membrane  apical plasma membrane  oxalate transmembrane transporter activity  oxalate transport  oxalate transport  PDZ domain binding  transepithelial chloride transport  transepithelial chloride transport  cytoplasmic vesicle membrane  brush border membrane  vesicle  chloride channel complex  epithelial fluid transport  regulation of membrane potential  oxalic acid secretion  sperm capacitation  intestinal absorption  regulation of intracellular pH  intracellular pH elevation  transepithelial transport  cellular response to cAMP  cellular response to fructose stimulus  cellular response to interferon-gamma  sperm midpiece  sulfate transmembrane transport  chloride transmembrane transport  positive regulation of dipeptide transmembrane transport  
Ontology : EGO-EBIchloride channel activity  inorganic anion exchanger activity  endoplasmic reticulum  plasma membrane  integral component of plasma membrane  ion transport  chloride transport  secondary active sulfate transmembrane transporter activity  sulfate transport  sulfate transport  vesicle membrane  bicarbonate transmembrane transporter activity  bicarbonate transmembrane transporter activity  chloride transmembrane transporter activity  chloride transmembrane transporter activity  sulfate transmembrane transporter activity  anion:anion antiporter activity  anion:anion antiporter activity  formate transmembrane transporter activity  efflux transmembrane transporter activity  formate uptake transmembrane transporter activity  formate efflux transmembrane transporter activity  bicarbonate transport  formate transport  mannitol transport  membrane  integral component of membrane  basolateral plasma membrane  apical plasma membrane  oxalate transmembrane transporter activity  oxalate transport  oxalate transport  PDZ domain binding  transepithelial chloride transport  transepithelial chloride transport  cytoplasmic vesicle membrane  brush border membrane  vesicle  chloride channel complex  epithelial fluid transport  regulation of membrane potential  oxalic acid secretion  sperm capacitation  intestinal absorption  regulation of intracellular pH  intracellular pH elevation  transepithelial transport  cellular response to cAMP  cellular response to fructose stimulus  cellular response to interferon-gamma  sperm midpiece  sulfate transmembrane transport  chloride transmembrane transport  positive regulation of dipeptide transmembrane transport  
Pathways : KEGGMineral absorption   
NDEx NetworkSLC26A6
Atlas of Cancer Signalling NetworkSLC26A6
Wikipedia pathwaysSLC26A6
Orthology - Evolution
OrthoDB65010
GeneTree (enSembl)ENSG00000225697
Phylogenetic Trees/Animal Genes : TreeFamSLC26A6
HOVERGENQ9BXS9
HOGENOMQ9BXS9
Homologs : HomoloGeneSLC26A6
Homology/Alignments : Family Browser (UCSC)SLC26A6
Gene fusions - Rearrangements
Fusion : MitelmanSLC26A6/PRKAR2A [3p21.31/3p21.31]  
Tumor Fusion PortalSLC26A6
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSLC26A6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SLC26A6
dbVarSLC26A6
ClinVarSLC26A6
1000_GenomesSLC26A6 
Exome Variant ServerSLC26A6
ExAC (Exome Aggregation Consortium)ENSG00000225697
GNOMAD BrowserENSG00000225697
Genetic variants : HAPMAP65010
Genomic Variants (DGV)SLC26A6 [DGVbeta]
DECIPHERSLC26A6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSLC26A6 
Mutations
ICGC Data PortalSLC26A6 
TCGA Data PortalSLC26A6 
Broad Tumor PortalSLC26A6
OASIS PortalSLC26A6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSLC26A6  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSLC26A6
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SLC26A6
DgiDB (Drug Gene Interaction Database)SLC26A6
DoCM (Curated mutations)SLC26A6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SLC26A6 (select a term)
intoGenSLC26A6
Cancer3DSLC26A6(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610068   
Orphanet
DisGeNETSLC26A6
MedgenSLC26A6
Genetic Testing Registry SLC26A6
NextProtQ9BXS9 [Medical]
TSGene65010
GENETestsSLC26A6
Target ValidationSLC26A6
Huge Navigator SLC26A6 [HugePedia]
snp3D : Map Gene to Disease65010
BioCentury BCIQSLC26A6
ClinGenSLC26A6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD65010
Chemical/Pharm GKB GenePA37889
Clinical trialSLC26A6
Miscellaneous
canSAR (ICR)SLC26A6 (select the gene name)
Probes
Litterature
PubMed30 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSLC26A6
EVEXSLC26A6
GoPubMedSLC26A6
iHOPSLC26A6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:35:03 CET 2017

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