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SLC27A1 (solute carrier family 27 (fatty acid transporter), member 1)

Identity

Alias_namessolute carrier family 27 (fatty acid transporter), member 1
Alias_symbol (synonym)FATP1
FATP
MGC71751
FLJ00336
ACSVL5
Other aliasFATP-1
HGNC (Hugo) SLC27A1
LocusID (NCBI) 376497
Atlas_Id 73378
Location 19p13.11  [Link to chromosome band 19p13]
Location_base_pair Starts at 17581253 and ends at 17616977 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
KCNN1 (19p13.11) / SLC27A1 (19p13.11)ZDHHC24 (11q13.2) / SLC27A1 (19p13.11)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SLC27A1   10995
Cards
Entrez_Gene (NCBI)SLC27A1  376497  solute carrier family 27 (fatty acid transporter), member 1
AliasesACSVL5; FATP; FATP-1; FATP1
GeneCards (Weizmann)SLC27A1
Ensembl hg19 (Hinxton)ENSG00000130304 [Gene_View]  chr19:17581253-17616977 [Contig_View]  SLC27A1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000130304 [Gene_View]  chr19:17581253-17616977 [Contig_View]  SLC27A1 [Vega]
ICGC DataPortalENSG00000130304
TCGA cBioPortalSLC27A1
AceView (NCBI)SLC27A1
Genatlas (Paris)SLC27A1
WikiGenes376497
SOURCE (Princeton)SLC27A1
Genetics Home Reference (NIH)SLC27A1
Genomic and cartography
GoldenPath hg19 (UCSC)SLC27A1  -     chr19:17581253-17616977 +  19p13.11   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)SLC27A1  -     19p13.11   [Description]    (hg38-Dec_2013)
EnsemblSLC27A1 - 19p13.11 [CytoView hg19]  SLC27A1 - 19p13.11 [CytoView hg38]
Mapping of homologs : NCBISLC27A1 [Mapview hg19]  SLC27A1 [Mapview hg38]
OMIM600691   
Gene and transcription
Genbank (Entrez)AK131101 AK294238 AK296355 AK299852 AK315935
RefSeq transcript (Entrez)NM_198580
RefSeq genomic (Entrez)NC_000019 NC_018930 NT_011295 NW_004929414
Consensus coding sequences : CCDS (NCBI)SLC27A1
Cluster EST : UnigeneHs.363138 [ NCBI ]
CGAP (NCI)Hs.363138
Alternative Splicing GalleryENSG00000130304
Gene ExpressionSLC27A1 [ NCBI-GEO ]   SLC27A1 [ EBI - ARRAY_EXPRESS ]   SLC27A1 [ SEEK ]   SLC27A1 [ MEM ]
Gene Expression Viewer (FireBrowse)SLC27A1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)376497
GTEX Portal (Tissue expression)SLC27A1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6PCB7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6PCB7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6PCB7
Splice isoforms : SwissVarQ6PCB7
Catalytic activity : Enzyme6.2.1.- [ Enzyme-Expasy ]   6.2.1.-6.2.1.- [ IntEnz-EBI ]   6.2.1.- [ BRENDA ]   6.2.1.- [ KEGG ]   
PhosPhoSitePlusQ6PCB7
Domaine pattern : Prosite (Expaxy)AMP_BINDING (PS00455)   
Domains : Interpro (EBI)AMP-bd_C    AMP-binding_CS    AMP-dep_Synth/Lig    FATP1   
Domain families : Pfam (Sanger)AMP-binding (PF00501)    AMP-binding_C (PF13193)   
Domain families : Pfam (NCBI)pfam00501    pfam13193   
Conserved Domain (NCBI)SLC27A1
DMDM Disease mutations376497
Blocks (Seattle)SLC27A1
SuperfamilyQ6PCB7
Human Protein AtlasENSG00000130304
Peptide AtlasQ6PCB7
HPRD11863
IPIIPI00442344   IPI00744434   IPI00061274   
Protein Interaction databases
DIP (DOE-UCLA)Q6PCB7
IntAct (EBI)Q6PCB7
FunCoupENSG00000130304
BioGRIDSLC27A1
STRING (EMBL)SLC27A1
ZODIACSLC27A1
Ontologies - Pathways
QuickGOQ6PCB7
Ontology : AmiGOnucleotide binding  medium-chain fatty acid transport  long-chain fatty acid metabolic process  long-chain fatty acid-CoA ligase activity  endoplasmic reticulum  plasma membrane  phosphatidylethanolamine biosynthetic process  phosphatidic acid biosynthetic process  phosphatidylglycerol biosynthetic process  phosphatidylcholine biosynthetic process  phosphatidylserine biosynthetic process  phosphatidylinositol biosynthetic process  response to cold  fatty acid transporter activity  long-chain fatty acid transport  membrane  integral component of membrane  positive regulation of heat generation  very long-chain fatty acid-CoA ligase activity  cardiolipin biosynthetic process  response to insulin  adiponectin-activated signaling pathway  protein homodimerization activity  cellular lipid metabolic process  small molecule metabolic process  transmembrane transport  negative regulation of phospholipid biosynthetic process  positive regulation of protein serine/threonine kinase activity  
Ontology : EGO-EBInucleotide binding  medium-chain fatty acid transport  long-chain fatty acid metabolic process  long-chain fatty acid-CoA ligase activity  endoplasmic reticulum  plasma membrane  phosphatidylethanolamine biosynthetic process  phosphatidic acid biosynthetic process  phosphatidylglycerol biosynthetic process  phosphatidylcholine biosynthetic process  phosphatidylserine biosynthetic process  phosphatidylinositol biosynthetic process  response to cold  fatty acid transporter activity  long-chain fatty acid transport  membrane  integral component of membrane  positive regulation of heat generation  very long-chain fatty acid-CoA ligase activity  cardiolipin biosynthetic process  response to insulin  adiponectin-activated signaling pathway  protein homodimerization activity  cellular lipid metabolic process  small molecule metabolic process  transmembrane transport  negative regulation of phospholipid biosynthetic process  positive regulation of protein serine/threonine kinase activity  
Pathways : KEGGPPAR signaling pathway   
NDEx NetworkSLC27A1
Atlas of Cancer Signalling NetworkSLC27A1
Wikipedia pathwaysSLC27A1
Orthology - Evolution
OrthoDB376497
GeneTree (enSembl)ENSG00000130304
Phylogenetic Trees/Animal Genes : TreeFamSLC27A1
HOVERGENQ6PCB7
HOGENOMQ6PCB7
Homologs : HomoloGeneSLC27A1
Homology/Alignments : Family Browser (UCSC)SLC27A1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSLC27A1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SLC27A1
dbVarSLC27A1
ClinVarSLC27A1
1000_GenomesSLC27A1 
Exome Variant ServerSLC27A1
ExAC (Exome Aggregation Consortium)SLC27A1 (select the gene name)
Genetic variants : HAPMAP376497
Genomic Variants (DGV)SLC27A1 [DGVbeta]
DECIPHER (Syndromes)19:17581253-17616977  ENSG00000130304
CONAN: Copy Number AnalysisSLC27A1 
Mutations
ICGC Data PortalSLC27A1 
TCGA Data PortalSLC27A1 
Broad Tumor PortalSLC27A1
OASIS PortalSLC27A1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSLC27A1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSLC27A1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SLC27A1
DgiDB (Drug Gene Interaction Database)SLC27A1
DoCM (Curated mutations)SLC27A1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SLC27A1 (select a term)
intoGenSLC27A1
Cancer3DSLC27A1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600691   
Orphanet
MedgenSLC27A1
Genetic Testing Registry SLC27A1
NextProtQ6PCB7 [Medical]
TSGene376497
GENETestsSLC27A1
Huge Navigator SLC27A1 [HugePedia]
snp3D : Map Gene to Disease376497
BioCentury BCIQSLC27A1
ClinGenSLC27A1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD376497
Chemical/Pharm GKB GenePA35869
Clinical trialSLC27A1
Miscellaneous
canSAR (ICR)SLC27A1 (select the gene name)
Probes
Litterature
PubMed25 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSLC27A1
EVEXSLC27A1
GoPubMedSLC27A1
iHOPSLC27A1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 12:43:36 CET 2017

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