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SLC27A2 (solute carrier family 27 member 2)

Identity

Alias_namesFACVL1
solute carrier family 27 (fatty acid transporter), member 2
Alias_symbol (synonym)FATP2
hFACVL1
VLACS
VLCS
HsT17226
ACSVL1
Other alias
HGNC (Hugo) SLC27A2
LocusID (NCBI) 11001
Atlas_Id 73379
Location 15q21.2  [Link to chromosome band 15q21]
Location_base_pair Starts at 50182196 and ends at 50236392 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
MAP1B (5q13.2) / SLC27A2 (15q21.2)RBM14 (11q13.2) / SLC27A2 (15q21.2)USP8 (15q21.2) / SLC27A2 (15q21.2)
USP8 SLC27A2MAP1B SLC27A2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SLC27A2   10996
Cards
Entrez_Gene (NCBI)SLC27A2  11001  solute carrier family 27 member 2
AliasesACSVL1; FACVL1; FATP2; HsT17226; 
VLACS; VLCS; hFACVL1
GeneCards (Weizmann)SLC27A2
Ensembl hg19 (Hinxton)ENSG00000140284 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000140284 [Gene_View]  chr15:50182196-50236392 [Contig_View]  SLC27A2 [Vega]
ICGC DataPortalENSG00000140284
TCGA cBioPortalSLC27A2
AceView (NCBI)SLC27A2
Genatlas (Paris)SLC27A2
WikiGenes11001
SOURCE (Princeton)SLC27A2
Genetics Home Reference (NIH)SLC27A2
Genomic and cartography
GoldenPath hg38 (UCSC)SLC27A2  -     chr15:50182196-50236392 +  15q21.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SLC27A2  -     15q21.2   [Description]    (hg19-Feb_2009)
EnsemblSLC27A2 - 15q21.2 [CytoView hg19]  SLC27A2 - 15q21.2 [CytoView hg38]
Mapping of homologs : NCBISLC27A2 [Mapview hg19]  SLC27A2 [Mapview hg38]
OMIM603247   
Gene and transcription
Genbank (Entrez)AF096290 AK123905 AK222859 AK223145 AK290262
RefSeq transcript (Entrez)NM_001159629 NM_003645
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SLC27A2
Cluster EST : UnigeneHs.11729 [ NCBI ]
CGAP (NCI)Hs.11729
Alternative Splicing GalleryENSG00000140284
Gene ExpressionSLC27A2 [ NCBI-GEO ]   SLC27A2 [ EBI - ARRAY_EXPRESS ]   SLC27A2 [ SEEK ]   SLC27A2 [ MEM ]
Gene Expression Viewer (FireBrowse)SLC27A2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)11001
GTEX Portal (Tissue expression)SLC27A2
Protein : pattern, domain, 3D structure
UniProt/SwissProtO14975   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO14975  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO14975
Splice isoforms : SwissVarO14975
Catalytic activity : Enzyme6.2.1.- [ Enzyme-Expasy ]   6.2.1.-6.2.1.- [ IntEnz-EBI ]   6.2.1.- [ BRENDA ]   6.2.1.- [ KEGG ]   
PhosPhoSitePlusO14975
Domaine pattern : Prosite (Expaxy)AMP_BINDING (PS00455)   
Domains : Interpro (EBI)AMP-bd_C    AMP-binding_CS    AMP-dep_Synth/Lig    FATP2   
Domain families : Pfam (Sanger)AMP-binding (PF00501)    AMP-binding_C (PF13193)   
Domain families : Pfam (NCBI)pfam00501    pfam13193   
Conserved Domain (NCBI)SLC27A2
DMDM Disease mutations11001
Blocks (Seattle)SLC27A2
SuperfamilyO14975
Human Protein AtlasENSG00000140284
Peptide AtlasO14975
HPRD11935
IPIIPI00024787   IPI01015450   IPI00447606   
Protein Interaction databases
DIP (DOE-UCLA)O14975
IntAct (EBI)O14975
FunCoupENSG00000140284
BioGRIDSLC27A2
STRING (EMBL)SLC27A2
ZODIACSLC27A2
Ontologies - Pathways
QuickGOO14975
Ontology : AmiGOfatty acid alpha-oxidation  fatty acid alpha-oxidation  long-chain fatty acid metabolic process  long-chain fatty acid-CoA ligase activity  long-chain fatty acid-CoA ligase activity  receptor binding  ATP binding  mitochondrion  peroxisomal membrane  peroxisomal membrane  integral component of peroxisomal membrane  endoplasmic reticulum lumen  endoplasmic reticulum membrane  endoplasmic reticulum membrane  plasma membrane  fatty acid beta-oxidation  bile acid biosynthetic process  bile acid biosynthetic process  fatty acid transporter activity  enzyme binding  integral component of endoplasmic reticulum membrane  very long-chain fatty acid-CoA ligase activity  specific granule membrane  very long-chain fatty acid catabolic process  neutrophil degranulation  long-chain fatty acid import  phytanate-CoA ligase activity  phytanate-CoA ligase activity  extracellular exosome  pristanate-CoA ligase activity  pristanate-CoA ligase activity  methyl-branched fatty acid metabolic process  decanoate--CoA ligase activity  
Ontology : EGO-EBIfatty acid alpha-oxidation  fatty acid alpha-oxidation  long-chain fatty acid metabolic process  long-chain fatty acid-CoA ligase activity  long-chain fatty acid-CoA ligase activity  receptor binding  ATP binding  mitochondrion  peroxisomal membrane  peroxisomal membrane  integral component of peroxisomal membrane  endoplasmic reticulum lumen  endoplasmic reticulum membrane  endoplasmic reticulum membrane  plasma membrane  fatty acid beta-oxidation  bile acid biosynthetic process  bile acid biosynthetic process  fatty acid transporter activity  enzyme binding  integral component of endoplasmic reticulum membrane  very long-chain fatty acid-CoA ligase activity  specific granule membrane  very long-chain fatty acid catabolic process  neutrophil degranulation  long-chain fatty acid import  phytanate-CoA ligase activity  phytanate-CoA ligase activity  extracellular exosome  pristanate-CoA ligase activity  pristanate-CoA ligase activity  methyl-branched fatty acid metabolic process  decanoate--CoA ligase activity  
Pathways : KEGGPPAR signaling pathway    Peroxisome   
NDEx NetworkSLC27A2
Atlas of Cancer Signalling NetworkSLC27A2
Wikipedia pathwaysSLC27A2
Orthology - Evolution
OrthoDB11001
GeneTree (enSembl)ENSG00000140284
Phylogenetic Trees/Animal Genes : TreeFamSLC27A2
HOVERGENO14975
HOGENOMO14975
Homologs : HomoloGeneSLC27A2
Homology/Alignments : Family Browser (UCSC)SLC27A2
Gene fusions - Rearrangements
Fusion: TCGAUSP8 SLC27A2
Fusion: TCGAMAP1B SLC27A2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSLC27A2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SLC27A2
dbVarSLC27A2
ClinVarSLC27A2
1000_GenomesSLC27A2 
Exome Variant ServerSLC27A2
ExAC (Exome Aggregation Consortium)SLC27A2 (select the gene name)
Genetic variants : HAPMAP11001
Genomic Variants (DGV)SLC27A2 [DGVbeta]
DECIPHERSLC27A2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSLC27A2 
Mutations
ICGC Data PortalSLC27A2 
TCGA Data PortalSLC27A2 
Broad Tumor PortalSLC27A2
OASIS PortalSLC27A2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSLC27A2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSLC27A2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SLC27A2
DgiDB (Drug Gene Interaction Database)SLC27A2
DoCM (Curated mutations)SLC27A2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SLC27A2 (select a term)
intoGenSLC27A2
Cancer3DSLC27A2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603247   
Orphanet
MedgenSLC27A2
Genetic Testing Registry SLC27A2
NextProtO14975 [Medical]
TSGene11001
GENETestsSLC27A2
Target ValidationSLC27A2
Huge Navigator SLC27A2 [HugePedia]
snp3D : Map Gene to Disease11001
BioCentury BCIQSLC27A2
ClinGenSLC27A2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD11001
Chemical/Pharm GKB GenePA27971
Clinical trialSLC27A2
Miscellaneous
canSAR (ICR)SLC27A2 (select the gene name)
Probes
Litterature
PubMed31 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSLC27A2
EVEXSLC27A2
GoPubMedSLC27A2
iHOPSLC27A2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:38:06 CEST 2017

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