Atlas of Genetics and Cytogenetics in Oncology and Haematology

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   
X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

SLC28A3 (solute carrier family 28 member 3)

Identity

Alias (NCBI)CNT3
HGNC (Hugo) SLC28A3
HGNC Alias symbCNT3
HGNC Previous namesolute carrier family 28 (sodium-coupled nucleoside transporter), member 3
 solute carrier family 28 (concentrative nucleoside transporter), member 3
LocusID (NCBI) 64078
Atlas_Id 50956
Location 9q21.32  [Link to chromosome band 9q21]
Location_base_pair Starts at 84275457 and ends at 84368727 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
MLLT3 (9p21.3) / SLC28A3 (9q21.32)SHB (9p13.2) / SLC28A3 (9q21.32)SLC28A3 (9q21.32) / SLC28A3 (9q21.32)
MLLT3 9p21.3 / SLC28A3 9q21.32SHB 9p13.2 / SLC28A3 9q21.32

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 2 ]
  t(9;9)(p13;q21) SHB/SLC28A3
t(9;9)(p21;q21) MLLT3/SLC28A3

External links

Nomenclature
HGNC (Hugo)SLC28A3   16484
Cards
Entrez_Gene (NCBI)SLC28A3    solute carrier family 28 member 3
AliasesCNT3
GeneCards (Weizmann)SLC28A3
Ensembl hg19 (Hinxton)ENSG00000197506 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000197506 [Gene_View]  ENSG00000197506 [Sequence]  chr9:84275457-84368727 [Contig_View]  SLC28A3 [Vega]
ICGC DataPortalENSG00000197506
TCGA cBioPortalSLC28A3
AceView (NCBI)SLC28A3
Genatlas (Paris)SLC28A3
SOURCE (Princeton)SLC28A3
Genetics Home Reference (NIH)SLC28A3
Genomic and cartography
GoldenPath hg38 (UCSC)SLC28A3  -     chr9:84275457-84368727 -  9q21.32   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SLC28A3  -     9q21.32   [Description]    (hg19-Feb_2009)
GoldenPathSLC28A3 - 9q21.32 [CytoView hg19]  SLC28A3 - 9q21.32 [CytoView hg38]
ImmunoBaseENSG00000197506
genome Data Viewer NCBISLC28A3 [Mapview hg19]  
OMIM608269   
Gene and transcription
Genbank (Entrez)AA643687 AF305210 AK022042 AK292849 AK304406
RefSeq transcript (Entrez)NM_001199633 NM_022127
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SLC28A3
Alternative Splicing GalleryENSG00000197506
Gene ExpressionSLC28A3 [ NCBI-GEO ]   SLC28A3 [ EBI - ARRAY_EXPRESS ]   SLC28A3 [ SEEK ]   SLC28A3 [ MEM ]
Gene Expression Viewer (FireBrowse)SLC28A3 [ Firebrowse - Broad ]
GenevisibleExpression of SLC28A3 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)64078
GTEX Portal (Tissue expression)SLC28A3
Human Protein AtlasENSG00000197506-SLC28A3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9HAS3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9HAS3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9HAS3
Splice isoforms : SwissVarQ9HAS3
PhosPhoSitePlusQ9HAS3
Domains : Interpro (EBI)C_nuclsd_transpt    C_nuclsd_transpt_met_bac    CNT3    CNT_C_dom    CNT_N_dom    Gate_dom   
Domain families : Pfam (Sanger)Gate (PF07670)    Nucleos_tra2_C (PF07662)    Nucleos_tra2_N (PF01773)   
Domain families : Pfam (NCBI)pfam07670    pfam07662    pfam01773   
Conserved Domain (NCBI)SLC28A3
Blocks (Seattle)SLC28A3
SuperfamilyQ9HAS3
Human Protein Atlas [tissue]ENSG00000197506-SLC28A3 [tissue]
Peptide AtlasQ9HAS3
HPRD12200
IPIIPI00005485   IPI01014059   
Protein Interaction databases
DIP (DOE-UCLA)Q9HAS3
IntAct (EBI)Q9HAS3
BioGRIDSLC28A3
STRING (EMBL)SLC28A3
ZODIACSLC28A3
Ontologies - Pathways
QuickGOQ9HAS3
Ontology : AmiGOnucleoside transmembrane transporter activity  nucleoside:sodium symporter activity  nucleoside:sodium symporter activity  endoplasmic reticulum membrane  plasma membrane  integral component of plasma membrane  symporter activity  pyrimidine- and adenine-specific:sodium symporter activity  purine-specific nucleoside:sodium symporter activity  pyrimidine nucleobase transport  purine nucleoside transmembrane transport  pyrimidine nucleoside transport  sodium ion transmembrane transport  pyrimidine-containing compound transmembrane transport  nucleoside transmembrane transport  purine nucleobase transmembrane transport  
Ontology : EGO-EBInucleoside transmembrane transporter activity  nucleoside:sodium symporter activity  nucleoside:sodium symporter activity  endoplasmic reticulum membrane  plasma membrane  integral component of plasma membrane  symporter activity  pyrimidine- and adenine-specific:sodium symporter activity  purine-specific nucleoside:sodium symporter activity  pyrimidine nucleobase transport  purine nucleoside transmembrane transport  pyrimidine nucleoside transport  sodium ion transmembrane transport  pyrimidine-containing compound transmembrane transport  nucleoside transmembrane transport  purine nucleobase transmembrane transport  
NDEx NetworkSLC28A3
Atlas of Cancer Signalling NetworkSLC28A3
Wikipedia pathwaysSLC28A3
Orthology - Evolution
OrthoDB64078
GeneTree (enSembl)ENSG00000197506
Phylogenetic Trees/Animal Genes : TreeFamSLC28A3
HOGENOMQ9HAS3
Homologs : HomoloGeneSLC28A3
Homology/Alignments : Family Browser (UCSC)SLC28A3
Gene fusions - Rearrangements
Fusion : MitelmanMLLT3/SLC28A3 [9p21.3/9q21.32]  
Fusion : MitelmanSHB/SLC28A3 [9p13.2/9q21.32]  
Fusion PortalMLLT3 9p21.3 SLC28A3 9q21.32 BRCA
Fusion PortalSHB 9p13.2 SLC28A3 9q21.32 BRCA
Fusion : QuiverSLC28A3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSLC28A3 [hg38]
dbVarSLC28A3
ClinVarSLC28A3
MonarchSLC28A3
1000_GenomesSLC28A3 
Exome Variant ServerSLC28A3
GNOMAD BrowserENSG00000197506
Varsome BrowserSLC28A3
Genomic Variants (DGV)SLC28A3 [DGVbeta]
DECIPHERSLC28A3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSLC28A3 
Mutations
ICGC Data PortalSLC28A3 
TCGA Data PortalSLC28A3 
Broad Tumor PortalSLC28A3
OASIS PortalSLC28A3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSLC28A3  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DSLC28A3
Mutations and Diseases : HGMDSLC28A3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SLC28A3
DgiDB (Drug Gene Interaction Database)SLC28A3
DoCM (Curated mutations)SLC28A3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SLC28A3 (select a term)
intoGenSLC28A3
Cancer3DSLC28A3(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608269   
Orphanet
DisGeNETSLC28A3
MedgenSLC28A3
Genetic Testing Registry SLC28A3
NextProtQ9HAS3 [Medical]
GENETestsSLC28A3
Target ValidationSLC28A3
Huge Navigator SLC28A3 [HugePedia]
ClinGenSLC28A3
Clinical trials, drugs, therapy
MyCancerGenomeSLC28A3
Protein Interactions : CTD
Pharm GKB GenePA426
Pharm GKB PathwaysPA165859361   PA2036   
PharosQ9HAS3
Clinical trialSLC28A3
Miscellaneous
canSAR (ICR)SLC28A3 (select the gene name)
HarmonizomeSLC28A3
DataMed IndexSLC28A3
Probes
Litterature
PubMed49 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXSLC28A3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jan 1 18:37:46 CET 2021
Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.