Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 222962
MIM: 609149
HGNC: 23097
Ensembl: ENSG00000164638
Variants:
dbSNP: 222962
ClinVar: 222962
TCGA: ENSG00000164638
COSMIC: SLC29A4
RNA/Proteins
Expression (GTEx)
Pathways
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA450395 | metformin | Chemical | Pathway | associated | 22722338 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37458617 | 2023 | PMAT variant rs3889348 is associated with metformin-induced gastrointestinal among Chinese Type 2 diabetes patients. | 0 |
| 37458617 | 2023 | PMAT variant rs3889348 is associated with metformin-induced gastrointestinal among Chinese Type 2 diabetes patients. | 0 |
| 34551672 | 2022 | Clinically significant findings of high-risk mutations in human SLC29A4 gene associated with diabetes mellitus type 2 in Pakistani population. | 4 |
| 34551672 | 2022 | Clinically significant findings of high-risk mutations in human SLC29A4 gene associated with diabetes mellitus type 2 in Pakistani population. | 4 |
| 30885951 | 2019 | Variation in the Plasma Membrane Monoamine Transporter (PMAT) (Encoded by SLC29A4) and Organic Cation Transporter 1 (OCT1) (Encoded by SLC22A1) and Gastrointestinal Intolerance to Metformin in Type 2 Diabetes: An IMI DIRECT Study. | 31 |
| 31537831 | 2019 | Bidirectional transport of 2-chloroadenosine by equilibrative nucleoside transporter 4 (hENT4): Evidence for allosteric kinetics at acidic pH. | 4 |
| 30885951 | 2019 | Variation in the Plasma Membrane Monoamine Transporter (PMAT) (Encoded by SLC29A4) and Organic Cation Transporter 1 (OCT1) (Encoded by SLC22A1) and Gastrointestinal Intolerance to Metformin in Type 2 Diabetes: An IMI DIRECT Study. | 31 |
| 31537831 | 2019 | Bidirectional transport of 2-chloroadenosine by equilibrative nucleoside transporter 4 (hENT4): Evidence for allosteric kinetics at acidic pH. | 4 |
| 24471494 | 2014 | Predominant role of plasma membrane monoamine transporters in monoamine transport in 1321N1, a human astrocytoma-derived cell line. | 13 |
| 24471494 | 2014 | Predominant role of plasma membrane monoamine transporters in monoamine transport in 1321N1, a human astrocytoma-derived cell line. | 13 |
| 21822668 | 2012 | Nucleoside transporters are widely expressed in ovarian carcinoma effusions. | 8 |
| 22562044 | 2012 | Residue Ile89 in human plasma membrane monoamine transporter influences its organic cation transport activity and sensitivity to inhibition by dilazep. | 2 |
| 21822668 | 2012 | Nucleoside transporters are widely expressed in ovarian carcinoma effusions. | 8 |
| 22562044 | 2012 | Residue Ile89 in human plasma membrane monoamine transporter influences its organic cation transport activity and sensitivity to inhibition by dilazep. | 2 |
| 20392501 | 2010 | Contribution of adenosine related genes to the risk of depression with disturbed sleep. | 23 |
Citation
Dessen P
SLC29A4 (solute carrier family 29 member 4)
Atlas Genet Cytogenet Oncol Haematol. 2008-09-01
Online version: http://atlasgeneticsoncology.org/gene/50322/slc29a4
