Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

SLC2A12 (solute carrier family 2 member 12)

Identity

Alias_namessolute carrier family 2 (facilitated glucose transporter)
Alias_symbol (synonym)GLUT12
GLUT8
Other alias
HGNC (Hugo) SLC2A12
LocusID (NCBI) 154091
Atlas_Id 51172
Location 6q23.2  [Link to chromosome band 6q23]
Location_base_pair Starts at 133987581 and ends at 134052651 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
SLC2A12 (6q23.2) / SGK1 (6q23.2)SLC2A12 (6q23.2) / ZNF236 (18q23)SLC2A12 6q23.2 / SGK1 6q23.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  SLC2A12/SGK1 (6q23)


External links

Nomenclature
HGNC (Hugo)SLC2A12   18067
Cards
Entrez_Gene (NCBI)SLC2A12  154091  solute carrier family 2 member 12
AliasesGLUT12; GLUT8
GeneCards (Weizmann)SLC2A12
Ensembl hg19 (Hinxton)ENSG00000146411 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000146411 [Gene_View]  ENSG00000146411 [Sequence]  chr6:133987581-134052651 [Contig_View]  SLC2A12 [Vega]
ICGC DataPortalENSG00000146411
TCGA cBioPortalSLC2A12
AceView (NCBI)SLC2A12
Genatlas (Paris)SLC2A12
WikiGenes154091
SOURCE (Princeton)SLC2A12
Genetics Home Reference (NIH)SLC2A12
Genomic and cartography
GoldenPath hg38 (UCSC)SLC2A12  -     chr6:133987581-134052651 -  6q23.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SLC2A12  -     6q23.2   [Description]    (hg19-Feb_2009)
EnsemblSLC2A12 - 6q23.2 [CytoView hg19]  SLC2A12 - 6q23.2 [CytoView hg38]
Mapping of homologs : NCBISLC2A12 [Mapview hg19]  SLC2A12 [Mapview hg38]
OMIM610372   
Gene and transcription
Genbank (Entrez)AK056554 AK122628 AK226098 AL833602 AY046419
RefSeq transcript (Entrez)NM_145176
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SLC2A12
Cluster EST : UnigeneHs.486508 [ NCBI ]
CGAP (NCI)Hs.486508
Alternative Splicing GalleryENSG00000146411
Gene ExpressionSLC2A12 [ NCBI-GEO ]   SLC2A12 [ EBI - ARRAY_EXPRESS ]   SLC2A12 [ SEEK ]   SLC2A12 [ MEM ]
Gene Expression Viewer (FireBrowse)SLC2A12 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)154091
GTEX Portal (Tissue expression)SLC2A12
Human Protein AtlasENSG00000146411-SLC2A12 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8TD20   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8TD20  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8TD20
Splice isoforms : SwissVarQ8TD20
PhosPhoSitePlusQ8TD20
Domaine pattern : Prosite (Expaxy)MFS (PS50850)    SUGAR_TRANSPORT_1 (PS00216)   
Domains : Interpro (EBI)MFS_dom    MFS_sugar_transport-like    MFS_trans_sf    Sugar/inositol_transpt    Sugar_transporter_CS   
Domain families : Pfam (Sanger)Sugar_tr (PF00083)   
Domain families : Pfam (NCBI)pfam00083   
Conserved Domain (NCBI)SLC2A12
DMDM Disease mutations154091
Blocks (Seattle)SLC2A12
SuperfamilyQ8TD20
Human Protein Atlas [tissue]ENSG00000146411-SLC2A12 [tissue]
Peptide AtlasQ8TD20
HPRD11572
IPIIPI00152424   
Protein Interaction databases
DIP (DOE-UCLA)Q8TD20
IntAct (EBI)Q8TD20
FunCoupENSG00000146411
BioGRIDSLC2A12
STRING (EMBL)SLC2A12
ZODIACSLC2A12
Ontologies - Pathways
QuickGOQ8TD20
Ontology : AmiGOcarbohydrate:proton symporter activity  plasma membrane  integral component of plasma membrane  hexose transmembrane transport  endomembrane system  perinuclear region of cytoplasm  D-glucose transmembrane transporter activity  proton transmembrane transport  glucose transmembrane transport  
Ontology : EGO-EBIcarbohydrate:proton symporter activity  plasma membrane  integral component of plasma membrane  hexose transmembrane transport  endomembrane system  perinuclear region of cytoplasm  D-glucose transmembrane transporter activity  proton transmembrane transport  glucose transmembrane transport  
NDEx NetworkSLC2A12
Atlas of Cancer Signalling NetworkSLC2A12
Wikipedia pathwaysSLC2A12
Orthology - Evolution
OrthoDB154091
GeneTree (enSembl)ENSG00000146411
Phylogenetic Trees/Animal Genes : TreeFamSLC2A12
HOVERGENQ8TD20
HOGENOMQ8TD20
Homologs : HomoloGeneSLC2A12
Homology/Alignments : Family Browser (UCSC)SLC2A12
Gene fusions - Rearrangements
Fusion : MitelmanSLC2A12/SGK1 [6q23.2/6q23.2]  
Fusion PortalSLC2A12 6q23.2 SGK1 6q23.2 HNSC
Fusion : QuiverSLC2A12
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSLC2A12 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SLC2A12
dbVarSLC2A12
ClinVarSLC2A12
1000_GenomesSLC2A12 
Exome Variant ServerSLC2A12
ExAC (Exome Aggregation Consortium)ENSG00000146411
GNOMAD BrowserENSG00000146411
Varsome BrowserSLC2A12
Genetic variants : HAPMAP154091
Genomic Variants (DGV)SLC2A12 [DGVbeta]
DECIPHERSLC2A12 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSLC2A12 
Mutations
ICGC Data PortalSLC2A12 
TCGA Data PortalSLC2A12 
Broad Tumor PortalSLC2A12
OASIS PortalSLC2A12 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSLC2A12  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSLC2A12
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SLC2A12
DgiDB (Drug Gene Interaction Database)SLC2A12
DoCM (Curated mutations)SLC2A12 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SLC2A12 (select a term)
intoGenSLC2A12
Cancer3DSLC2A12(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610372   
Orphanet
DisGeNETSLC2A12
MedgenSLC2A12
Genetic Testing Registry SLC2A12
NextProtQ8TD20 [Medical]
TSGene154091
GENETestsSLC2A12
Target ValidationSLC2A12
Huge Navigator SLC2A12 [HugePedia]
snp3D : Map Gene to Disease154091
BioCentury BCIQSLC2A12
ClinGenSLC2A12
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD154091
Chemical/Pharm GKB GenePA38288
Clinical trialSLC2A12
Miscellaneous
canSAR (ICR)SLC2A12 (select the gene name)
Probes
Litterature
PubMed22 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSLC2A12
EVEXSLC2A12
GoPubMedSLC2A12
iHOPSLC2A12
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 6 11:39:48 CET 2018

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.