SLC2A14 (solute carrier family 2 member 14)

2016-10-01  

Identity

HGNC
SLC2A14
LOCATION
12p13.31
LOCUSID
144195
ALIAS
GLUT14,SLC2A3P3
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 144195
MIM: 611039
HGNC: 18301
Ensembl: ENSG00000173262

Variants:

dbSNP: 144195
ClinVar: 144195
TCGA: ENSG00000173262
COSMIC: SLC2A14

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000173262ENST00000340749Q8TDB8
ENSG00000173262ENST00000396589Q8TDB8
ENSG00000173262ENST00000431042Q8TDB8
ENSG00000173262ENST00000535266F5H6F6
ENSG00000173262ENST00000535295Q8TDB8
ENSG00000173262ENST00000535344F5H5Q3
ENSG00000173262ENST00000535383F5H5V7
ENSG00000173262ENST00000535587F5H3J0
ENSG00000173262ENST00000536594F5GXT4
ENSG00000173262ENST00000537557F5GXP7
ENSG00000173262ENST00000539234F5H565
ENSG00000173262ENST00000539924Q8TDB8
ENSG00000173262ENST00000542505Q8TDB8
ENSG00000173262ENST00000542546Q8TDB8
ENSG00000173262ENST00000542782F5H076
ENSG00000173262ENST00000542916F5H7N2
ENSG00000173262ENST00000543909Q8TDB8
ENSG00000173262ENST00000546234F5GXP8
ENSG00000173262ENST00000616981Q8TDB8

Expression (GTEx)

0
10
20
30
40
50
60
70
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Transmembrane transport of small moleculesREACTOMER-HSA-382551
SLC-mediated transmembrane transportREACTOMER-HSA-425407
Hexose transportREACTOMER-HSA-189200
Glucose transportREACTOMER-HSA-70153
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compoundsREACTOMER-HSA-425366
Facilitative Na+-independent glucose transportersREACTOMER-HSA-428790
MetabolismREACTOMER-HSA-1430728
Metabolism of carbohydratesREACTOMER-HSA-71387

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
261838392015Both GLUT-1 and GLUT-14 are Independent Prognostic Factors in Gastric Adenocarcinoma.11
224218042012Genetic association of SLC2A14 polymorphism with Alzheimer's disease in a Han Chinese population.6
289718502017The SLC2A14 gene, encoding the novel glucose/dehydroascorbate transporter GLUT14, is associated with inflammatory bowel disease.6
274608882016The SLC2A14 gene: genomic locus, tissue expression, splice variants, and subcellular localization of the protein.4
308859922019Adaptation to HIF1α Deletion in Hypoxic Cancer Cells by Upregulation of GLUT14 and Creatine Metabolism.2

Citation

Dessen P

SLC2A14 (solute carrier family 2 member 14)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56625/slc2a14