Atlas of Genetics and Cytogenetics in Oncology and Haematology


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SLC2A3 (solute carrier family 2 member 3)

Identity

Alias_namesGLUT3
solute carrier family 2 (facilitated glucose transporter)
Other alias
HGNC (Hugo) SLC2A3
LocusID (NCBI) 6515
Atlas_Id 42319
Location 12p13.31  [Link to chromosome band 12p13]
Location_base_pair Starts at 7919228 and ends at 7936296 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
IGFBP3 (7p12.3) / SLC2A3 (12p13.31)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SLC2A3   11007
Cards
Entrez_Gene (NCBI)SLC2A3  6515  solute carrier family 2 member 3
AliasesGLUT3
GeneCards (Weizmann)SLC2A3
Ensembl hg19 (Hinxton)ENSG00000059804 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000059804 [Gene_View]  ENSG00000059804 [Sequence]  chr12:7919228-7936296 [Contig_View]  SLC2A3 [Vega]
ICGC DataPortalENSG00000059804
TCGA cBioPortalSLC2A3
AceView (NCBI)SLC2A3
Genatlas (Paris)SLC2A3
WikiGenes6515
SOURCE (Princeton)SLC2A3
Genetics Home Reference (NIH)SLC2A3
Genomic and cartography
GoldenPath hg38 (UCSC)SLC2A3  -     chr12:7919228-7936296 -  12p13.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SLC2A3  -     12p13.31   [Description]    (hg19-Feb_2009)
EnsemblSLC2A3 - 12p13.31 [CytoView hg19]  SLC2A3 - 12p13.31 [CytoView hg38]
Mapping of homologs : NCBISLC2A3 [Mapview hg19]  SLC2A3 [Mapview hg38]
OMIM138170   
Gene and transcription
Genbank (Entrez)AB209607 AK074861 AK298673 AK304509 AK312386
RefSeq transcript (Entrez)NM_006931
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SLC2A3
Cluster EST : UnigeneHs.419240 [ NCBI ]
CGAP (NCI)Hs.419240
Alternative Splicing GalleryENSG00000059804
Gene ExpressionSLC2A3 [ NCBI-GEO ]   SLC2A3 [ EBI - ARRAY_EXPRESS ]   SLC2A3 [ SEEK ]   SLC2A3 [ MEM ]
Gene Expression Viewer (FireBrowse)SLC2A3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6515
GTEX Portal (Tissue expression)SLC2A3
Human Protein AtlasENSG00000059804-SLC2A3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP11169   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP11169  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP11169
Splice isoforms : SwissVarP11169
PhosPhoSitePlusP11169
Domaine pattern : Prosite (Expaxy)MFS (PS50850)    SUGAR_TRANSPORT_1 (PS00216)    SUGAR_TRANSPORT_2 (PS00217)   
Domains : Interpro (EBI)Glc_transpt_3    MFS_dom    MFS_sugar_transport-like    MFS_trans_sf    Sugar/inositol_transpt    Sugar_transporter_CS   
Domain families : Pfam (Sanger)Sugar_tr (PF00083)   
Domain families : Pfam (NCBI)pfam00083   
Conserved Domain (NCBI)SLC2A3
DMDM Disease mutations6515
Blocks (Seattle)SLC2A3
PDB (SRS)4ZW9    4ZWB    4ZWC    5C65   
PDB (PDBSum)4ZW9    4ZWB    4ZWC    5C65   
PDB (IMB)4ZW9    4ZWB    4ZWC    5C65   
PDB (RSDB)4ZW9    4ZWB    4ZWC    5C65   
Structural Biology KnowledgeBase4ZW9    4ZWB    4ZWC    5C65   
SCOP (Structural Classification of Proteins)4ZW9    4ZWB    4ZWC    5C65   
CATH (Classification of proteins structures)4ZW9    4ZWB    4ZWC    5C65   
SuperfamilyP11169
Human Protein Atlas [tissue]ENSG00000059804-SLC2A3 [tissue]
Peptide AtlasP11169
HPRD00686
IPIIPI00003909   IPI01011292   IPI00816836   IPI01013234   IPI01015976   
Protein Interaction databases
DIP (DOE-UCLA)P11169
IntAct (EBI)P11169
FunCoupENSG00000059804
BioGRIDSLC2A3
STRING (EMBL)SLC2A3
ZODIACSLC2A3
Ontologies - Pathways
QuickGOP11169
Ontology : AmiGOglucose transmembrane transporter activity  glucose binding  plasma membrane  integral component of plasma membrane  carbohydrate metabolic process  integral component of membrane  L-ascorbic acid metabolic process  secretory granule membrane  dehydroascorbic acid transmembrane transporter activity  specific granule membrane  neutrophil degranulation  D-glucose transmembrane transporter activity  extracellular exosome  tertiary granule membrane  dehydroascorbic acid transport  ficolin-1-rich granule membrane  glucose transmembrane transport  glucose transmembrane transport  
Ontology : EGO-EBIglucose transmembrane transporter activity  glucose binding  plasma membrane  integral component of plasma membrane  carbohydrate metabolic process  integral component of membrane  L-ascorbic acid metabolic process  secretory granule membrane  dehydroascorbic acid transmembrane transporter activity  specific granule membrane  neutrophil degranulation  D-glucose transmembrane transporter activity  extracellular exosome  tertiary granule membrane  dehydroascorbic acid transport  ficolin-1-rich granule membrane  glucose transmembrane transport  glucose transmembrane transport  
NDEx NetworkSLC2A3
Atlas of Cancer Signalling NetworkSLC2A3
Wikipedia pathwaysSLC2A3
Orthology - Evolution
OrthoDB6515
GeneTree (enSembl)ENSG00000059804
Phylogenetic Trees/Animal Genes : TreeFamSLC2A3
HOVERGENP11169
HOGENOMP11169
Homologs : HomoloGeneSLC2A3
Homology/Alignments : Family Browser (UCSC)SLC2A3
Gene fusions - Rearrangements
Fusion : QuiverSLC2A3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSLC2A3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SLC2A3
dbVarSLC2A3
ClinVarSLC2A3
1000_GenomesSLC2A3 
Exome Variant ServerSLC2A3
ExAC (Exome Aggregation Consortium)ENSG00000059804
GNOMAD BrowserENSG00000059804
Varsome BrowserSLC2A3
Genetic variants : HAPMAP6515
Genomic Variants (DGV)SLC2A3 [DGVbeta]
DECIPHERSLC2A3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSLC2A3 
Mutations
ICGC Data PortalSLC2A3 
TCGA Data PortalSLC2A3 
Broad Tumor PortalSLC2A3
OASIS PortalSLC2A3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSLC2A3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSLC2A3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SLC2A3
DgiDB (Drug Gene Interaction Database)SLC2A3
DoCM (Curated mutations)SLC2A3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SLC2A3 (select a term)
intoGenSLC2A3
Cancer3DSLC2A3(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM138170   
Orphanet118   
DisGeNETSLC2A3
MedgenSLC2A3
Genetic Testing Registry SLC2A3
NextProtP11169 [Medical]
TSGene6515
GENETestsSLC2A3
Target ValidationSLC2A3
Huge Navigator SLC2A3 [HugePedia]
snp3D : Map Gene to Disease6515
BioCentury BCIQSLC2A3
ClinGenSLC2A3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6515
Chemical/Pharm GKB GenePA35877
Clinical trialSLC2A3
Miscellaneous
canSAR (ICR)SLC2A3 (select the gene name)
Probes
Litterature
PubMed97 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSLC2A3
EVEXSLC2A3
GoPubMedSLC2A3
iHOPSLC2A3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 6 11:39:49 CET 2018

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