Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

SLC2A5 (solute carrier family 2 member 5)

Identity

Alias_namesGLUT5
solute carrier family 2 (facilitated glucose/fructose transporter)
Other aliasGLUT-5
HGNC (Hugo) SLC2A5
LocusID (NCBI) 6518
Atlas_Id 42320
Location 1p36.23  [Link to chromosome band 1p36]
Location_base_pair Starts at 9036946 and ends at 9069828 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ITM2C (2q37.1) / SLC2A5 (1p36.23)RERE (1p36.23) / SLC2A5 (1p36.23)TRIM11 (1q42.13) / SLC2A5 (1p36.23)
RERE 1p36.23 / SLC2A5 1p36.23TRIM11 1q42.13 / SLC2A5 1p36.23

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 3 ]
  Lung: Translocations in Small Cell Carcinoma
RERE/SLC2A5 (1p36)
t(1;1)(p36;q42) TRIM11/SLC2A5


External links

Nomenclature
HGNC (Hugo)SLC2A5   11010
Cards
Entrez_Gene (NCBI)SLC2A5  6518  solute carrier family 2 member 5
AliasesGLUT-5; GLUT5
GeneCards (Weizmann)SLC2A5
Ensembl hg19 (Hinxton)ENSG00000142583 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000142583 [Gene_View]  ENSG00000142583 [Sequence]  chr1:9036946-9069828 [Contig_View]  SLC2A5 [Vega]
ICGC DataPortalENSG00000142583
TCGA cBioPortalSLC2A5
AceView (NCBI)SLC2A5
Genatlas (Paris)SLC2A5
WikiGenes6518
SOURCE (Princeton)SLC2A5
Genetics Home Reference (NIH)SLC2A5
Genomic and cartography
GoldenPath hg38 (UCSC)SLC2A5  -     chr1:9036946-9069828 -  1p36.23   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SLC2A5  -     1p36.23   [Description]    (hg19-Feb_2009)
GoldenPathSLC2A5 - 1p36.23 [CytoView hg19]  SLC2A5 - 1p36.23 [CytoView hg38]
ImmunoBaseENSG00000142583
Mapping of homologs : NCBISLC2A5 [Mapview hg19]  SLC2A5 [Mapview hg38]
OMIM138230   
Gene and transcription
Genbank (Entrez)AF451839 AF479408 AK289849 AK290398 AK294368
RefSeq transcript (Entrez)NM_001135585 NM_001328619 NM_001328620 NM_001328621 NM_003039
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SLC2A5
Cluster EST : UnigeneHs.530003 [ NCBI ]
CGAP (NCI)Hs.530003
Alternative Splicing GalleryENSG00000142583
Gene ExpressionSLC2A5 [ NCBI-GEO ]   SLC2A5 [ EBI - ARRAY_EXPRESS ]   SLC2A5 [ SEEK ]   SLC2A5 [ MEM ]
Gene Expression Viewer (FireBrowse)SLC2A5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6518
GTEX Portal (Tissue expression)SLC2A5
Human Protein AtlasENSG00000142583-SLC2A5 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP22732   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP22732  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP22732
Splice isoforms : SwissVarP22732
PhosPhoSitePlusP22732
Domaine pattern : Prosite (Expaxy)MFS (PS50850)    SUGAR_TRANSPORT_1 (PS00216)    SUGAR_TRANSPORT_2 (PS00217)   
Domains : Interpro (EBI)Fru_transpt_5    MFS_dom    MFS_sugar_transport-like    MFS_trans_sf    Sugar/inositol_transpt    Sugar_transporter_CS   
Domain families : Pfam (Sanger)Sugar_tr (PF00083)   
Domain families : Pfam (NCBI)pfam00083   
Conserved Domain (NCBI)SLC2A5
DMDM Disease mutations6518
Blocks (Seattle)SLC2A5
PDB (RSDB)1YG1   
PDB Europe1YG1   
PDB (PDBSum)1YG1   
PDB (IMB)1YG1   
Structural Biology KnowledgeBase1YG1   
SCOP (Structural Classification of Proteins)1YG1   
CATH (Classification of proteins structures)1YG1   
SuperfamilyP22732
Human Protein Atlas [tissue]ENSG00000142583-SLC2A5 [tissue]
Peptide AtlasP22732
HPRD00690
IPIIPI00027452   IPI00909644   IPI01018961   IPI00953406   IPI01011573   IPI00383409   
Protein Interaction databases
DIP (DOE-UCLA)P22732
IntAct (EBI)P22732
FunCoupENSG00000142583
BioGRIDSLC2A5
STRING (EMBL)SLC2A5
ZODIACSLC2A5
Ontologies - Pathways
QuickGOP22732
Ontology : AmiGOregulation of systemic arterial blood pressure mediated by a chemical signal  fructose transmembrane transporter activity  fructose transmembrane transporter activity  fructose transmembrane transporter activity  glucose transmembrane transporter activity  plasma membrane  integral component of plasma membrane  carbohydrate metabolic process  response to fructose  fructose transmembrane transport  apical plasma membrane  specific granule membrane  sarcolemma  neutrophil degranulation  fructose binding  extracellular exosome  cellular response to fructose stimulus  intestinal hexose absorption  glucose transmembrane transport  fructose import across plasma membrane  
Ontology : EGO-EBIregulation of systemic arterial blood pressure mediated by a chemical signal  fructose transmembrane transporter activity  fructose transmembrane transporter activity  fructose transmembrane transporter activity  glucose transmembrane transporter activity  plasma membrane  integral component of plasma membrane  carbohydrate metabolic process  response to fructose  fructose transmembrane transport  apical plasma membrane  specific granule membrane  sarcolemma  neutrophil degranulation  fructose binding  extracellular exosome  cellular response to fructose stimulus  intestinal hexose absorption  glucose transmembrane transport  fructose import across plasma membrane  
Pathways : KEGGCarbohydrate digestion and absorption   
NDEx NetworkSLC2A5
Atlas of Cancer Signalling NetworkSLC2A5
Wikipedia pathwaysSLC2A5
Orthology - Evolution
OrthoDB6518
GeneTree (enSembl)ENSG00000142583
Phylogenetic Trees/Animal Genes : TreeFamSLC2A5
HOGENOMP22732
Homologs : HomoloGeneSLC2A5
Homology/Alignments : Family Browser (UCSC)SLC2A5
Gene fusions - Rearrangements
Fusion : MitelmanRERE/SLC2A5 [1p36.23/1p36.23]  [t(1;1)(p36;p36)]  
Fusion : MitelmanTRIM11/SLC2A5 [1q42.13/1p36.23]  [t(1;1)(p36;q42)]  
Fusion PortalRERE 1p36.23 SLC2A5 1p36.23 LUAD
Fusion PortalTRIM11 1q42.13 SLC2A5 1p36.23 BRCA
Fusion : QuiverSLC2A5
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSLC2A5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SLC2A5
dbVarSLC2A5
ClinVarSLC2A5
1000_GenomesSLC2A5 
Exome Variant ServerSLC2A5
ExAC (Exome Aggregation Consortium)ENSG00000142583
GNOMAD BrowserENSG00000142583
Varsome BrowserSLC2A5
Genetic variants : HAPMAP6518
Genomic Variants (DGV)SLC2A5 [DGVbeta]
DECIPHERSLC2A5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSLC2A5 
Mutations
ICGC Data PortalSLC2A5 
TCGA Data PortalSLC2A5 
Broad Tumor PortalSLC2A5
OASIS PortalSLC2A5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSLC2A5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSLC2A5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SLC2A5
DgiDB (Drug Gene Interaction Database)SLC2A5
DoCM (Curated mutations)SLC2A5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SLC2A5 (select a term)
intoGenSLC2A5
Cancer3DSLC2A5(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM138230   
Orphanet
DisGeNETSLC2A5
MedgenSLC2A5
Genetic Testing Registry SLC2A5
NextProtP22732 [Medical]
TSGene6518
GENETestsSLC2A5
Target ValidationSLC2A5
Huge Navigator SLC2A5 [HugePedia]
snp3D : Map Gene to Disease6518
BioCentury BCIQSLC2A5
ClinGenSLC2A5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6518
Chemical/Pharm GKB GenePA35880
Clinical trialSLC2A5
Miscellaneous
canSAR (ICR)SLC2A5 (select the gene name)
DataMed IndexSLC2A5
Probes
Litterature
PubMed39 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSLC2A5
EVEXSLC2A5
GoPubMedSLC2A5
iHOPSLC2A5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jun 7 18:17:22 CEST 2019

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.