SLC2A9 (solute carrier family 2 member 9)

2015-06-01  

Identity

HGNC
LOCATION
4p16.1
LOCUSID
ALIAS
GLUT9,GLUTX,UAQTL2,URATv1
FUSION GENES

Other Information

Locus ID:

NCBI: 56606
MIM: 606142
HGNC: 13446
Ensembl: ENSG00000109667

Variants:

dbSNP: 56606
ClinVar: 56606
TCGA: ENSG00000109667
COSMIC: SLC2A9

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000109667ENST00000264784Q9NRM0
ENSG00000109667ENST00000309065Q9NRM0
ENSG00000109667ENST00000506583Q9NRM0
ENSG00000109667ENST00000513129D6REK5

Expression (GTEx)

0
1
2
3
4
5
6

Pathways

PathwaySourceExternal ID
Transmembrane transport of small moleculesREACTOMER-HSA-382551
SLC-mediated transmembrane transportREACTOMER-HSA-425407
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compoundsREACTOMER-HSA-425366
Facilitative Na+-independent glucose transportersREACTOMER-HSA-428790
Class II GLUTsREACTOMER-HSA-428776

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
183272572008SLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and gout.246
183272572008SLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and gout.246
195035972009Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations.228
188346262008Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study.221
181798922008Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia.190
183272562008SLC2A9 influences uric acid concentrations with pronounced sex-specific effects.158
183272562008SLC2A9 influences uric acid concentrations with pronounced sex-specific effects.158
208848462010Multiple genetic loci influence serum urate levels and their relationship with gout and cardiovascular disease risk factors.135
179976082007The GLUT9 gene is associated with serum uric acid levels in Sardinia and Chianti cohorts.113
179976082007The GLUT9 gene is associated with serum uric acid levels in Sardinia and Chianti cohorts.113

Citation

Dessen P

SLC2A9 (solute carrier family 2 member 9)

Atlas Genet Cytogenet Oncol Haematol. 2015-06-01

Online version: http://atlasgeneticsoncology.org/gene/55281/slc2a9