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SLC30A8 (solute carrier family 30 member 8)

Identity

Alias_namessolute carrier family 30 (zinc transporter), member 8
Other aliasZNT8
ZnT-8
HGNC (Hugo) SLC30A8
LocusID (NCBI) 169026
Atlas_Id 73392
Location 8q24.11  [Link to chromosome band 8q24]
Location_base_pair Starts at 116950273 and ends at 117176714 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SLC30A8   20303
Cards
Entrez_Gene (NCBI)SLC30A8  169026  solute carrier family 30 member 8
AliasesZNT8; ZnT-8
GeneCards (Weizmann)SLC30A8
Ensembl hg19 (Hinxton)ENSG00000164756 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000164756 [Gene_View]  chr8:116950273-117176714 [Contig_View]  SLC30A8 [Vega]
ICGC DataPortalENSG00000164756
TCGA cBioPortalSLC30A8
AceView (NCBI)SLC30A8
Genatlas (Paris)SLC30A8
WikiGenes169026
SOURCE (Princeton)SLC30A8
Genetics Home Reference (NIH)SLC30A8
Genomic and cartography
GoldenPath hg38 (UCSC)SLC30A8  -     chr8:116950273-117176714 +  8q24.11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SLC30A8  -     8q24.11   [Description]    (hg19-Feb_2009)
EnsemblSLC30A8 - 8q24.11 [CytoView hg19]  SLC30A8 - 8q24.11 [CytoView hg38]
Mapping of homologs : NCBISLC30A8 [Mapview hg19]  SLC30A8 [Mapview hg38]
OMIM125853   611145   
Gene and transcription
Genbank (Entrez)AK298294 AL713790 AM392521 AM393307 AY117411
RefSeq transcript (Entrez)NM_001172811 NM_001172813 NM_001172814 NM_001172815 NM_173851
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SLC30A8
Cluster EST : UnigeneHs.532270 [ NCBI ]
CGAP (NCI)Hs.532270
Alternative Splicing GalleryENSG00000164756
Gene ExpressionSLC30A8 [ NCBI-GEO ]   SLC30A8 [ EBI - ARRAY_EXPRESS ]   SLC30A8 [ SEEK ]   SLC30A8 [ MEM ]
Gene Expression Viewer (FireBrowse)SLC30A8 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)169026
GTEX Portal (Tissue expression)SLC30A8
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8IWU4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8IWU4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8IWU4
Splice isoforms : SwissVarQ8IWU4
PhosPhoSitePlusQ8IWU4
Domains : Interpro (EBI)Cation_efflux    Cation_efflux_TMD    ZnT-8   
Domain families : Pfam (Sanger)Cation_efflux (PF01545)   
Domain families : Pfam (NCBI)pfam01545   
Conserved Domain (NCBI)SLC30A8
DMDM Disease mutations169026
Blocks (Seattle)SLC30A8
SuperfamilyQ8IWU4
Human Protein AtlasENSG00000164756
Peptide AtlasQ8IWU4
HPRD15370
IPIIPI00217394   IPI00829922   IPI00976737   
Protein Interaction databases
DIP (DOE-UCLA)Q8IWU4
IntAct (EBI)Q8IWU4
FunCoupENSG00000164756
BioGRIDSLC30A8
STRING (EMBL)SLC30A8
ZODIACSLC30A8
Ontologies - Pathways
QuickGOQ8IWU4
Ontology : AmiGOzinc ion transmembrane transporter activity  zinc ion transmembrane transporter activity  protein binding  Golgi apparatus  plasma membrane  zinc II ion transport  cellular zinc ion homeostasis  zinc ion binding  response to glucose  response to zinc ion  integral component of membrane  insulin secretion  secretory granule  transport vesicle membrane  secretory granule membrane  cytoplasmic vesicle  positive regulation of insulin secretion  sequestering of zinc ion  response to interferon-gamma  glucose homeostasis  protein homodimerization activity  regulation of vesicle-mediated transport  regulation of sequestering of zinc ion  regulation of sequestering of zinc ion  response to interleukin-1  zinc II ion transmembrane transport  
Ontology : EGO-EBIzinc ion transmembrane transporter activity  zinc ion transmembrane transporter activity  protein binding  Golgi apparatus  plasma membrane  zinc II ion transport  cellular zinc ion homeostasis  zinc ion binding  response to glucose  response to zinc ion  integral component of membrane  insulin secretion  secretory granule  transport vesicle membrane  secretory granule membrane  cytoplasmic vesicle  positive regulation of insulin secretion  sequestering of zinc ion  response to interferon-gamma  glucose homeostasis  protein homodimerization activity  regulation of vesicle-mediated transport  regulation of sequestering of zinc ion  regulation of sequestering of zinc ion  response to interleukin-1  zinc II ion transmembrane transport  
NDEx NetworkSLC30A8
Atlas of Cancer Signalling NetworkSLC30A8
Wikipedia pathwaysSLC30A8
Orthology - Evolution
OrthoDB169026
GeneTree (enSembl)ENSG00000164756
Phylogenetic Trees/Animal Genes : TreeFamSLC30A8
HOVERGENQ8IWU4
HOGENOMQ8IWU4
Homologs : HomoloGeneSLC30A8
Homology/Alignments : Family Browser (UCSC)SLC30A8
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSLC30A8 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SLC30A8
dbVarSLC30A8
ClinVarSLC30A8
1000_GenomesSLC30A8 
Exome Variant ServerSLC30A8
ExAC (Exome Aggregation Consortium)SLC30A8 (select the gene name)
Genetic variants : HAPMAP169026
Genomic Variants (DGV)SLC30A8 [DGVbeta]
DECIPHERSLC30A8 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSLC30A8 
Mutations
ICGC Data PortalSLC30A8 
TCGA Data PortalSLC30A8 
Broad Tumor PortalSLC30A8
OASIS PortalSLC30A8 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSLC30A8  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSLC30A8
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch SLC30A8
DgiDB (Drug Gene Interaction Database)SLC30A8
DoCM (Curated mutations)SLC30A8 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SLC30A8 (select a term)
intoGenSLC30A8
Cancer3DSLC30A8(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM125853    611145   
Orphanet
MedgenSLC30A8
Genetic Testing Registry SLC30A8
NextProtQ8IWU4 [Medical]
TSGene169026
GENETestsSLC30A8
Target ValidationSLC30A8
Huge Navigator SLC30A8 [HugePedia]
snp3D : Map Gene to Disease169026
BioCentury BCIQSLC30A8
ClinGenSLC30A8
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD169026
Chemical/Pharm GKB GenePA134915546
Clinical trialSLC30A8
Miscellaneous
canSAR (ICR)SLC30A8 (select the gene name)
Probes
Litterature
PubMed188 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSLC30A8
EVEXSLC30A8
GoPubMedSLC30A8
iHOPSLC30A8
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed May 31 15:41:11 CEST 2017

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