Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1317
MIM: 603085
HGNC: 11016
Ensembl: ENSG00000136868
Variants:
dbSNP: 1317
ClinVar: 1317
TCGA: ENSG00000136868
COSMIC: SLC31A1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000136868 | ENST00000374212 | O15431 |
| ENSG00000136868 | ENST00000374212 | A0A024R824 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA164713176 | Platinum compounds | Chemical | ClinicalAnnotation, Pathway, VariantAnnotation | ambiguous | PD | 19525887 | |
| PA166123026 | progression-free survival | Disease | VariantAnnotation | not associated | PD | ||
| PA166123207 | overall survival | Disease | ClinicalAnnotation, VariantAnnotation | ambiguous | PD | ||
| PA443340 | Anemia | Disease | ClinicalAnnotation | associated | PD | ||
| PA443622 | Carcinoma, Non-Small-Cell Lung | Disease | ClinicalAnnotation, VariantAnnotation | ambiguous | PD | 22516052, 22725681 | |
| PA443937 | Drug Toxicity | Disease | ClinicalAnnotation | associated | PD | ||
| PA444773 | Leukopenia | Disease | ClinicalAnnotation | associated | PD | ||
| PA445048 | Nausea | Disease | ClinicalAnnotation | associated | PD | ||
| PA445113 | Neutropenia | Disease | ClinicalAnnotation | associated | PD | ||
| PA445846 | Thrombocytopenia | Disease | ClinicalAnnotation, VariantAnnotation | associated | PD | ||
| PA446051 | Vomiting | Disease | ClinicalAnnotation | associated | PD | ||
| PA448803 | carboplatin | Chemical | ClinicalAnnotation | associated | PD | 22725681 | |
| PA449014 | cisplatin | Chemical | ClinicalAnnotation | associated | PD | 22516052, 22725681 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38712735 | 2024 | Revealing the potential of solute carrier family 31 (copper transporters), member 1: Insights into its role in bladder cancer progression and therapeutic implications. | 1 |
| 38712735 | 2024 | Revealing the potential of solute carrier family 31 (copper transporters), member 1: Insights into its role in bladder cancer progression and therapeutic implications. | 1 |
| 37610668 | 2023 | Cuproptosis-related gene SLC31A1 expression correlates with the prognosis and tumor immune microenvironment in glioma. | 4 |
| 37853210 | 2023 | Cuproptosis-related gene SLC31A1: prognosis values and potential biological functions in cancer. | 2 |
| 37884650 | 2023 | Identification of cuproptosis-related gene SLC31A1 and upstream LncRNA-miRNA regulatory axis in breast cancer. | 1 |
| 37610668 | 2023 | Cuproptosis-related gene SLC31A1 expression correlates with the prognosis and tumor immune microenvironment in glioma. | 4 |
| 37853210 | 2023 | Cuproptosis-related gene SLC31A1: prognosis values and potential biological functions in cancer. | 2 |
| 37884650 | 2023 | Identification of cuproptosis-related gene SLC31A1 and upstream LncRNA-miRNA regulatory axis in breast cancer. | 1 |
| 35996075 | 2022 | High expression of cuproptosis-related SLC31A1 gene in relation to unfavorable outcome and deregulated immune cell infiltration in breast cancer: an analysis based on public databases. | 21 |
| 35996075 | 2022 | High expression of cuproptosis-related SLC31A1 gene in relation to unfavorable outcome and deregulated immune cell infiltration in breast cancer: an analysis based on public databases. | 21 |
| 33404748 | 2021 | Dual-mode imaging of copper transporter 1 in HepG2 cells by hyphenating confocal laser scanning microscopy with laser ablation ICPMS. | 1 |
| 33411033 | 2021 | Effects of SLC31A1 and ATP7B polymorphisms on platinum resistance in patients with esophageal squamous cell carcinoma receiving neoadjuvant chemoradiotherapy. | 5 |
| 33434736 | 2021 | Abnormalities in the copper transporter CTR1 in postmortem hippocampus in schizophrenia: A subregion and laminar analysis. | 4 |
| 33404748 | 2021 | Dual-mode imaging of copper transporter 1 in HepG2 cells by hyphenating confocal laser scanning microscopy with laser ablation ICPMS. | 1 |
| 33411033 | 2021 | Effects of SLC31A1 and ATP7B polymorphisms on platinum resistance in patients with esophageal squamous cell carcinoma receiving neoadjuvant chemoradiotherapy. | 5 |
Citation
Dessen P
SLC31A1 (solute carrier family 31 member 1)
Atlas Genet Cytogenet Oncol Haematol. 2009-08-01
Online version: http://atlasgeneticsoncology.org/gene/50996/slc31a1
