Atlas of Genetics and Cytogenetics in Oncology and Haematology


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SLC32A1 (solute carrier family 32 member 1)

Identity

Alias_namesVIAAT
vesicular inhibitory amino acid transporter
solute carrier family 32 (GABA vesicular transporter), member 1
Alias_symbol (synonym)VGAT
bA122O1.1
Other alias
HGNC (Hugo) SLC32A1
LocusID (NCBI) 140679
Atlas_Id 73393
Location 20q11.23  [Link to chromosome band 20q11]
Location_base_pair Starts at 38724462 and ends at 38729372 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SLC32A1   11018
Cards
Entrez_Gene (NCBI)SLC32A1  140679  solute carrier family 32 member 1
AliasesVGAT; VIAAT
GeneCards (Weizmann)SLC32A1
Ensembl hg19 (Hinxton)ENSG00000101438 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000101438 [Gene_View]  chr20:38724462-38729372 [Contig_View]  SLC32A1 [Vega]
ICGC DataPortalENSG00000101438
TCGA cBioPortalSLC32A1
AceView (NCBI)SLC32A1
Genatlas (Paris)SLC32A1
WikiGenes140679
SOURCE (Princeton)SLC32A1
Genetics Home Reference (NIH)SLC32A1
Genomic and cartography
GoldenPath hg38 (UCSC)SLC32A1  -     chr20:38724462-38729372 +  20q11.23   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SLC32A1  -     20q11.23   [Description]    (hg19-Feb_2009)
EnsemblSLC32A1 - 20q11.23 [CytoView hg19]  SLC32A1 - 20q11.23 [CytoView hg38]
Mapping of homologs : NCBISLC32A1 [Mapview hg19]  SLC32A1 [Mapview hg38]
OMIM616440   
Gene and transcription
Genbank (Entrez)AF064848 AK055051 AK091079 AY044836 BC036458
RefSeq transcript (Entrez)NM_080552
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SLC32A1
Cluster EST : UnigeneHs.179080 [ NCBI ]
CGAP (NCI)Hs.179080
Alternative Splicing GalleryENSG00000101438
Gene ExpressionSLC32A1 [ NCBI-GEO ]   SLC32A1 [ EBI - ARRAY_EXPRESS ]   SLC32A1 [ SEEK ]   SLC32A1 [ MEM ]
Gene Expression Viewer (FireBrowse)SLC32A1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)140679
GTEX Portal (Tissue expression)SLC32A1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H598   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H598  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H598
Splice isoforms : SwissVarQ9H598
PhosPhoSitePlusQ9H598
Domains : Interpro (EBI)AA_transpt_TM   
Domain families : Pfam (Sanger)Aa_trans (PF01490)   
Domain families : Pfam (NCBI)pfam01490   
Conserved Domain (NCBI)SLC32A1
DMDM Disease mutations140679
Blocks (Seattle)SLC32A1
SuperfamilyQ9H598
Human Protein AtlasENSG00000101438
Peptide AtlasQ9H598
HPRD18058
IPIIPI00026015   
Protein Interaction databases
DIP (DOE-UCLA)Q9H598
IntAct (EBI)Q9H598
FunCoupENSG00000101438
BioGRIDSLC32A1
STRING (EMBL)SLC32A1
ZODIACSLC32A1
Ontologies - Pathways
QuickGOQ9H598
Ontology : AmiGOamino acid transmembrane transport  vesicular hydrogen:amino acid antiporter activity  plasma membrane  ion transport  neurotransmitter secretion  aging  synaptic vesicle  amino acid transmembrane transporter activity  amino acid transmembrane transporter activity  glycine transmembrane transporter activity  gamma-aminobutyric acid:proton symporter activity  gamma-aminobutyric acid transport  glycine transport  amine transport  hippocampus development  integral component of synaptic vesicle membrane  dendrite  synaptic vesicle membrane  neuron projection  dendrite terminus  neuron projection terminus  cone cell pedicle  presynaptic active zone  cell tip  inhibitory synapse  clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane  neurotransmitter loading into synaptic vesicle  
Ontology : EGO-EBIamino acid transmembrane transport  vesicular hydrogen:amino acid antiporter activity  plasma membrane  ion transport  neurotransmitter secretion  aging  synaptic vesicle  amino acid transmembrane transporter activity  amino acid transmembrane transporter activity  glycine transmembrane transporter activity  gamma-aminobutyric acid:proton symporter activity  gamma-aminobutyric acid transport  glycine transport  amine transport  hippocampus development  integral component of synaptic vesicle membrane  dendrite  synaptic vesicle membrane  neuron projection  dendrite terminus  neuron projection terminus  cone cell pedicle  presynaptic active zone  cell tip  inhibitory synapse  clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane  neurotransmitter loading into synaptic vesicle  
Pathways : KEGGSynaptic vesicle cycle    Retrograde endocannabinoid signaling    GABAergic synapse    Morphine addiction    Nicotine addiction   
NDEx NetworkSLC32A1
Atlas of Cancer Signalling NetworkSLC32A1
Wikipedia pathwaysSLC32A1
Orthology - Evolution
OrthoDB140679
GeneTree (enSembl)ENSG00000101438
Phylogenetic Trees/Animal Genes : TreeFamSLC32A1
HOVERGENQ9H598
HOGENOMQ9H598
Homologs : HomoloGeneSLC32A1
Homology/Alignments : Family Browser (UCSC)SLC32A1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSLC32A1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SLC32A1
dbVarSLC32A1
ClinVarSLC32A1
1000_GenomesSLC32A1 
Exome Variant ServerSLC32A1
ExAC (Exome Aggregation Consortium)SLC32A1 (select the gene name)
Genetic variants : HAPMAP140679
Genomic Variants (DGV)SLC32A1 [DGVbeta]
DECIPHERSLC32A1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSLC32A1 
Mutations
ICGC Data PortalSLC32A1 
TCGA Data PortalSLC32A1 
Broad Tumor PortalSLC32A1
OASIS PortalSLC32A1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSLC32A1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSLC32A1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SLC32A1
DgiDB (Drug Gene Interaction Database)SLC32A1
DoCM (Curated mutations)SLC32A1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SLC32A1 (select a term)
intoGenSLC32A1
Cancer3DSLC32A1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616440   
Orphanet
MedgenSLC32A1
Genetic Testing Registry SLC32A1
NextProtQ9H598 [Medical]
TSGene140679
GENETestsSLC32A1
Target ValidationSLC32A1
Huge Navigator SLC32A1 [HugePedia]
snp3D : Map Gene to Disease140679
BioCentury BCIQSLC32A1
ClinGenSLC32A1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD140679
Chemical/Pharm GKB GenePA401
Clinical trialSLC32A1
Miscellaneous
canSAR (ICR)SLC32A1 (select the gene name)
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSLC32A1
EVEXSLC32A1
GoPubMedSLC32A1
iHOPSLC32A1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 31 15:41:12 CEST 2017

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