SLC36A4 (solute carrier family 36 member 4)

2016-10-01  

Identity

HGNC
LOCATION
11q21
LOCUSID
ALIAS
PAT4
FUSION GENES

Other Information

Locus ID:

NCBI: 120103
MIM: 613760
HGNC: 19660
Ensembl: ENSG00000180773

Variants:

dbSNP: 120103
ClinVar: 120103
TCGA: ENSG00000180773
COSMIC: SLC36A4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000180773ENST00000326402Q6YBV0
ENSG00000180773ENST00000524875E9PN09
ENSG00000180773ENST00000529184Q6YBV0
ENSG00000180773ENST00000534116E9PID7

Expression (GTEx)

0
5
10
15
20

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
204986352010Proton-assisted amino-acid transporters are conserved regulators of proliferation and amino-acid-dependent mTORC1 activation.58
210975002011SLC36A4 (hPAT4) is a high affinity amino acid transporter when expressed in Xenopus laevis oocytes.17
264345942016PAT4 levels control amino-acid sensitivity of rapamycin-resistant mTORC1 from the Golgi and affect clinical outcome in colorectal cancer.17

Citation

Dessen P

SLC36A4 (solute carrier family 36 member 4)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56370/slc36a4