Atlas of Genetics and Cytogenetics in Oncology and Haematology

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SLC37A4 (solute carrier family 37 member 4)

Identity

Alias (NCBI)G6PT1
G6PT2
G6PT3
GSD1b
GSD1c
GSD1d
PRO0685
TRG-19
TRG19
HGNC (Hugo) SLC37A4
HGNC Alias symbGSD1b
GSD1c
GSD1d
HGNC Previous nameG6PT1
 G6PT2
 G6PT3
HGNC Previous nameglucose-6-phosphatase, transport (glucose-6-phosphate) protein 1
 solute carrier family 37 (glucose-6-phosphate transporter), member 4
LocusID (NCBI) 2542
Atlas_Id 47556
Location 11q23.3  [Link to chromosome band 11q23]
Location_base_pair Starts at 119024112 and ends at 119030877 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Cancer prone implicated (Data extracted from papers in the Atlas) [ 1 ]
  Glycogen storage disease type I (GSD I)

External links

Nomenclature
HGNC (Hugo)SLC37A4   4061
LRG (Locus Reference Genomic)LRG_187
Cards
Entrez_Gene (NCBI)SLC37A4  2542  solute carrier family 37 member 4
AliasesG6PT1; G6PT2; G6PT3; GSD1b; 
GSD1c; GSD1d; PRO0685; TRG-19; TRG19
GeneCards (Weizmann)SLC37A4
Ensembl hg19 (Hinxton)ENSG00000137700 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000137700 [Gene_View]  ENSG00000137700 [Sequence]  chr11:119024112-119030877 [Contig_View]  SLC37A4 [Vega]
ICGC DataPortalENSG00000137700
TCGA cBioPortalSLC37A4
AceView (NCBI)SLC37A4
Genatlas (Paris)SLC37A4
WikiGenes2542
SOURCE (Princeton)SLC37A4
Genetics Home Reference (NIH)SLC37A4
Genomic and cartography
GoldenPath hg38 (UCSC)SLC37A4  -     chr11:119024112-119030877 -  11q23.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SLC37A4  -     11q23.3   [Description]    (hg19-Feb_2009)
GoldenPathSLC37A4 - 11q23.3 [CytoView hg19]  SLC37A4 - 11q23.3 [CytoView hg38]
ImmunoBaseENSG00000137700
genome Data Viewer NCBISLC37A4 [Mapview hg19]  
OMIM232220   232240   602671   
Gene and transcription
Genbank (Entrez)AB209026 AF110819 AF110820 AF110821 AF110822
RefSeq transcript (Entrez)NM_001164277 NM_001164278 NM_001164279 NM_001164280 NM_001467
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SLC37A4
Alternative Splicing GalleryENSG00000137700
Gene ExpressionSLC37A4 [ NCBI-GEO ]   SLC37A4 [ EBI - ARRAY_EXPRESS ]   SLC37A4 [ SEEK ]   SLC37A4 [ MEM ]
Gene Expression Viewer (FireBrowse)SLC37A4 [ Firebrowse - Broad ]
GenevisibleExpression of SLC37A4 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2542
GTEX Portal (Tissue expression)SLC37A4
Human Protein AtlasENSG00000137700-SLC37A4 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO43826   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO43826  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO43826
Splice isoforms : SwissVarO43826
PhosPhoSitePlusO43826
Domaine pattern : Prosite (Expaxy)GLPT (PS00942)    MFS (PS50850)   
Domains : Interpro (EBI)MFS    MFS_dom    MFS_trans_sf    Sugar-P_transporter_CS    Sugar_P_transporter   
Domain families : Pfam (Sanger)MFS_1 (PF07690)   
Domain families : Pfam (NCBI)pfam07690   
Conserved Domain (NCBI)SLC37A4
DMDM Disease mutations2542
Blocks (Seattle)SLC37A4
SuperfamilyO43826
Human Protein Atlas [tissue]ENSG00000137700-SLC37A4 [tissue]
Peptide AtlasO43826
HPRD04052
IPIIPI00014479   IPI00217409   IPI00556237   IPI00943754   
Protein Interaction databases
DIP (DOE-UCLA)O43826
IntAct (EBI)O43826
FunCoupENSG00000137700
BioGRIDSLC37A4
STRING (EMBL)SLC37A4
ZODIACSLC37A4
Ontologies - Pathways
QuickGOO43826
Ontology : AmiGOendoplasmic reticulum  endoplasmic reticulum membrane  glucose metabolic process  gluconeogenesis  carbohydrate transport  glucose-6-phosphate transmembrane transporter activity  glucose-6-phosphate transport  glucose-6-phosphate transport  glucose-6-phosphate transport  membrane  integral component of membrane  integral component of endoplasmic reticulum membrane  phosphate ion transmembrane transport  glucose 6-phosphate:inorganic phosphate antiporter activity  glucose 6-phosphate:inorganic phosphate antiporter activity  
Ontology : EGO-EBIendoplasmic reticulum  endoplasmic reticulum membrane  glucose metabolic process  gluconeogenesis  carbohydrate transport  glucose-6-phosphate transmembrane transporter activity  glucose-6-phosphate transport  glucose-6-phosphate transport  glucose-6-phosphate transport  membrane  integral component of membrane  integral component of endoplasmic reticulum membrane  phosphate ion transmembrane transport  glucose 6-phosphate:inorganic phosphate antiporter activity  glucose 6-phosphate:inorganic phosphate antiporter activity  
Pathways : KEGGCarbohydrate digestion and absorption   
NDEx NetworkSLC37A4
Atlas of Cancer Signalling NetworkSLC37A4
Wikipedia pathwaysSLC37A4
Orthology - Evolution
OrthoDB2542
GeneTree (enSembl)ENSG00000137700
Phylogenetic Trees/Animal Genes : TreeFamSLC37A4
HOGENOMO43826
Homologs : HomoloGeneSLC37A4
Homology/Alignments : Family Browser (UCSC)SLC37A4
Gene fusions - Rearrangements
Fusion : QuiverSLC37A4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSLC37A4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SLC37A4
dbVarSLC37A4
ClinVarSLC37A4
1000_GenomesSLC37A4 
Exome Variant ServerSLC37A4
GNOMAD BrowserENSG00000137700
Varsome BrowserSLC37A4
Genetic variants : HAPMAP2542
Genomic Variants (DGV)SLC37A4 [DGVbeta]
DECIPHERSLC37A4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSLC37A4 
Mutations
ICGC Data PortalSLC37A4 
TCGA Data PortalSLC37A4 
Broad Tumor PortalSLC37A4
OASIS PortalSLC37A4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSLC37A4  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DSLC37A4
Mutations and Diseases : HGMDSLC37A4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Mendelian genes
LOVD (Leiden Open Variation Database)**PUBLIC** CCHMC Molecular Genetics Laboratory Mutation Database
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch SLC37A4
DgiDB (Drug Gene Interaction Database)SLC37A4
DoCM (Curated mutations)SLC37A4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SLC37A4 (select a term)
intoGenSLC37A4
Cancer3DSLC37A4(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM232220    232240    602671   
Orphanet11285   
DisGeNETSLC37A4
MedgenSLC37A4
Genetic Testing Registry SLC37A4
NextProtO43826 [Medical]
TSGene2542
GENETestsSLC37A4
Target ValidationSLC37A4
Huge Navigator SLC37A4 [HugePedia]
snp3D : Map Gene to Disease2542
BioCentury BCIQSLC37A4
ClinGenSLC37A4
Clinical trials, drugs, therapy
Protein Interactions : CTD2542
Pharm GKB GenePA28472
Clinical trialSLC37A4
Miscellaneous
canSAR (ICR)SLC37A4 (select the gene name)
HarmonizomeSLC37A4
DataMed IndexSLC37A4
Probes
Litterature
PubMed61 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSLC37A4
EVEXSLC37A4
GoPubMedSLC37A4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Thu Jul 16 15:36:14 CEST 2020
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