Atlas of Genetics and Cytogenetics in Oncology and Haematology


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SLC38A3 (solute carrier family 38 member 3)

Identity

Alias_namessolute carrier family 38
Alias_symbol (synonym)G17
SN1
Other aliasNAT1
SNAT3
HGNC (Hugo) SLC38A3
LocusID (NCBI) 10991
Atlas_Id 45952
Location 3p21.31  [Link to chromosome band 3p21]
Location_base_pair Starts at 50242679 and ends at 50258411 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
PSENEN (19q13.12) / SLC38A3 (3p21.31)RBM6 (3p21.31) / SLC38A3 (3p21.31)SLC38A3 (3p21.31) / SLC38A3 (3p21.31)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SLC38A3   18044
Cards
Entrez_Gene (NCBI)SLC38A3  10991  solute carrier family 38 member 3
AliasesG17; NAT1; SN1; SNAT3
GeneCards (Weizmann)SLC38A3
Ensembl hg19 (Hinxton)ENSG00000188338 [Gene_View]  chr3:50242679-50258411 [Contig_View]  SLC38A3 [Vega]
Ensembl hg38 (Hinxton)ENSG00000188338 [Gene_View]  chr3:50242679-50258411 [Contig_View]  SLC38A3 [Vega]
ICGC DataPortalENSG00000188338
TCGA cBioPortalSLC38A3
AceView (NCBI)SLC38A3
Genatlas (Paris)SLC38A3
WikiGenes10991
SOURCE (Princeton)SLC38A3
Genetics Home Reference (NIH)SLC38A3
Genomic and cartography
GoldenPath hg19 (UCSC)SLC38A3  -     chr3:50242679-50258411 +  3p21.31   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)SLC38A3  -     3p21.31   [Description]    (hg38-Dec_2013)
EnsemblSLC38A3 - 3p21.31 [CytoView hg19]  SLC38A3 - 3p21.31 [CytoView hg38]
Mapping of homologs : NCBISLC38A3 [Mapview hg19]  SLC38A3 [Mapview hg38]
OMIM604437   
Gene and transcription
Genbank (Entrez)AF244548 AK293801 AK299677 AK313461 AM392752
RefSeq transcript (Entrez)NM_006841
RefSeq genomic (Entrez)NC_000003 NC_018914 NT_022517 NW_004929309
Consensus coding sequences : CCDS (NCBI)SLC38A3
Cluster EST : UnigeneHs.76460 [ NCBI ]
CGAP (NCI)Hs.76460
Alternative Splicing GalleryENSG00000188338
Gene ExpressionSLC38A3 [ NCBI-GEO ]   SLC38A3 [ EBI - ARRAY_EXPRESS ]   SLC38A3 [ SEEK ]   SLC38A3 [ MEM ]
Gene Expression Viewer (FireBrowse)SLC38A3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10991
GTEX Portal (Tissue expression)SLC38A3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ99624   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ99624  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ99624
Splice isoforms : SwissVarQ99624
PhosPhoSitePlusQ99624
Domains : Interpro (EBI)AA_transpt_TM   
Domain families : Pfam (Sanger)Aa_trans (PF01490)   
Domain families : Pfam (NCBI)pfam01490   
Conserved Domain (NCBI)SLC38A3
DMDM Disease mutations10991
Blocks (Seattle)SLC38A3
SuperfamilyQ99624
Human Protein AtlasENSG00000188338
Peptide AtlasQ99624
HPRD11980
IPIIPI00186295   
Protein Interaction databases
DIP (DOE-UCLA)Q99624
IntAct (EBI)Q99624
FunCoupENSG00000188338
BioGRIDSLC38A3
STRING (EMBL)SLC38A3
ZODIACSLC38A3
Ontologies - Pathways
QuickGOQ99624
Ontology : AmiGOamino acid transmembrane transport  L-histidine transmembrane transporter activity  plasma membrane  plasma membrane  integral component of plasma membrane  integral component of plasma membrane  sodium ion transport  amino acid transport  asparagine transport  glutamine transport  brain development  female pregnancy  amino acid transmembrane transporter activity  L-alanine transmembrane transporter activity  L-asparagine transmembrane transporter activity  L-glutamine transmembrane transporter activity  symporter activity  antiporter activity  L-alanine transport  histidine transport  basolateral plasma membrane  cellular response to potassium ion starvation  positive regulation of transcription from RNA polymerase II promoter in response to acidic pH  L-histidine transmembrane transport  L-histidine transmembrane transport  positive regulation of glutamine transport  
Ontology : EGO-EBIamino acid transmembrane transport  L-histidine transmembrane transporter activity  plasma membrane  plasma membrane  integral component of plasma membrane  integral component of plasma membrane  sodium ion transport  amino acid transport  asparagine transport  glutamine transport  brain development  female pregnancy  amino acid transmembrane transporter activity  L-alanine transmembrane transporter activity  L-asparagine transmembrane transporter activity  L-glutamine transmembrane transporter activity  symporter activity  antiporter activity  L-alanine transport  histidine transport  basolateral plasma membrane  cellular response to potassium ion starvation  positive regulation of transcription from RNA polymerase II promoter in response to acidic pH  L-histidine transmembrane transport  L-histidine transmembrane transport  positive regulation of glutamine transport  
Pathways : KEGGGlutamatergic synapse    GABAergic synapse    Proximal tubule bicarbonate reclamation   
NDEx NetworkSLC38A3
Atlas of Cancer Signalling NetworkSLC38A3
Wikipedia pathwaysSLC38A3
Orthology - Evolution
OrthoDB10991
GeneTree (enSembl)ENSG00000188338
Phylogenetic Trees/Animal Genes : TreeFamSLC38A3
HOVERGENQ99624
HOGENOMQ99624
Homologs : HomoloGeneSLC38A3
Homology/Alignments : Family Browser (UCSC)SLC38A3
Gene fusions - Rearrangements
Fusion : MitelmanRBM6/SLC38A3 [3p21.31/3p21.31]  [t(3;3)(p21;p21)]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSLC38A3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SLC38A3
dbVarSLC38A3
ClinVarSLC38A3
1000_GenomesSLC38A3 
Exome Variant ServerSLC38A3
ExAC (Exome Aggregation Consortium)SLC38A3 (select the gene name)
Genetic variants : HAPMAP10991
Genomic Variants (DGV)SLC38A3 [DGVbeta]
DECIPHER (Syndromes)3:50242679-50258411  ENSG00000188338
CONAN: Copy Number AnalysisSLC38A3 
Mutations
ICGC Data PortalSLC38A3 
TCGA Data PortalSLC38A3 
Broad Tumor PortalSLC38A3
OASIS PortalSLC38A3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSLC38A3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSLC38A3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SLC38A3
DgiDB (Drug Gene Interaction Database)SLC38A3
DoCM (Curated mutations)SLC38A3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SLC38A3 (select a term)
intoGenSLC38A3
Cancer3DSLC38A3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604437   
Orphanet
MedgenSLC38A3
Genetic Testing Registry SLC38A3
NextProtQ99624 [Medical]
TSGene10991
GENETestsSLC38A3
Huge Navigator SLC38A3 [HugePedia]
snp3D : Map Gene to Disease10991
BioCentury BCIQSLC38A3
ClinGenSLC38A3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10991
Chemical/Pharm GKB GenePA38281
Clinical trialSLC38A3
Miscellaneous
canSAR (ICR)SLC38A3 (select the gene name)
Probes
Litterature
PubMed22 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSLC38A3
EVEXSLC38A3
GoPubMedSLC38A3
iHOPSLC38A3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:27:53 CET 2017

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