SLC38A4 (solute carrier family 38 member 4)

2009-05-01  

Identity

HGNC
LOCATION
12q13.11
LOCUSID
ALIAS
ATA3,NAT3,PAAT,SNAT4

Other Information

Locus ID:

NCBI: 55089
MIM: 608065
HGNC: 14679
Ensembl: ENSG00000139209

Variants:

dbSNP: 55089
ClinVar: 55089
TCGA: ENSG00000139209
COSMIC: SLC38A4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000139209ENST00000266579Q969I6
ENSG00000139209ENST00000266579A0A024R0X7
ENSG00000139209ENST00000447411Q969I6
ENSG00000139209ENST00000447411A0A024R0X7
ENSG00000139209ENST00000546940F8VRD9
ENSG00000139209ENST00000547477F8VQY9
ENSG00000139209ENST00000550670H0YHZ8

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
Transmembrane transport of small moleculesREACTOMER-HSA-382551
SLC-mediated transmembrane transportREACTOMER-HSA-425407
Transport of inorganic cations/anions and amino acids/oligopeptidesREACTOMER-HSA-425393
Amino acid transport across the plasma membraneREACTOMER-HSA-352230

References

Pubmed IDYearTitleCitations
161480322006SNAT4 isoform of system A amino acid transporter is expressed in human placenta.40
190151962009The SNAT4 isoform of the system A amino acid transporter is functional in human placental microvillous plasma membrane.23
250638482014PAAT, a novel ATPase and trans-regulator of mitochondrial ABC transporters, is critically involved in the maintenance of mitochondrial homeostasis.6
219179172011Membrane topological structure of neutral system N/A amino acid transporter 4 (SNAT4) protein.3
187039942009Amino acid transport systems beta and A in fetal T lymphocytes in intrauterine growth restriction and with tumor necrosis factor-alpha treatment.2
229456942013Association of the polymorphisms 292 C>T and 1304 G>A in the SLC38A4 gene with hyperglycaemia.1
275875432016Polymorphisms in cancer-related pathway genes and lung cancer.1

Citation

Dessen P

SLC38A4 (solute carrier family 38 member 4)

Atlas Genet Cytogenet Oncol Haematol. 2009-05-01

Online version: http://atlasgeneticsoncology.org/gene/50890/slc38a4