SLC39A10 (solute carrier family 39 member 10)

2015-02-01  

Identity

HGNC
SLC39A10
LOCATION
2q32.3
LOCUSID
57181
ALIAS
LZT-Hs2
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 57181
MIM: 608733
HGNC: 20861
Ensembl: ENSG00000196950

Variants:

dbSNP: 57181
ClinVar: 57181
TCGA: ENSG00000196950
COSMIC: SLC39A10

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000196950ENST00000359634Q9ULF5
ENSG00000196950ENST00000359634A0A024R3W5
ENSG00000196950ENST00000409086Q9ULF5
ENSG00000196950ENST00000409086A0A024R3W5
ENSG00000196950ENST00000412905C9J0F5
ENSG00000196950ENST00000418005E7EV45
ENSG00000196950ENST00000430412F2Z341
ENSG00000196950ENST00000444421F2Z341
ENSG00000196950ENST00000458054E7ENT5

Expression (GTEx)

0
5
10
15
20
25
30
35
40
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Transmembrane transport of small moleculesREACTOMER-HSA-382551
SLC-mediated transmembrane transportREACTOMER-HSA-425407
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compoundsREACTOMER-HSA-425366
Metal ion SLC transportersREACTOMER-HSA-425410
Zinc transportersREACTOMER-HSA-435354
Zinc influx into cells by the SLC39 gene familyREACTOMER-HSA-442380

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
190645712008Polymorphisms in mitochondrial genes and prostate cancer risk.20
245872422014High glucose level promotes migration behavior of breast cancer cells through zinc and its transporters.15
291804212017Metal transporter Slc39a10 regulates susceptibility to inflammatory stimuli by controlling macrophage survival.6
252004962014Association between ZIP10 gene expression and tumor aggressiveness in renal cell carcinoma.5
305206572019Cloning, function, and localization of human, canine, and Drosophila ZIP10 (SLC39A10), a Zn2+ transporter.1

Citation

Dessen P

SLC39A10 (solute carrier family 39 member 10)

Atlas Genet Cytogenet Oncol Haematol. 2015-02-01

Online version: http://atlasgeneticsoncology.org/gene/54968/slc39a10