SLC45A3 (solute carrier family 45 member 3)

2003-02-01  

Identity

HGNC
LOCATION
1q32.1
LOCUSID
ALIAS
IPCA-2,IPCA-6,IPCA-8,IPCA6,PCANAP2,PCANAP6,PCANAP8,PRST
FUSION GENES

Other Information

Locus ID:

NCBI: 85414
MIM: 605097
HGNC: 8642
Ensembl: ENSG00000158715

Variants:

dbSNP: 85414
ClinVar: 85414
TCGA: ENSG00000158715
COSMIC: SLC45A3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000158715ENST00000367145Q96JT2

Expression (GTEx)

0
50
100
150
200
250

Pathways

PathwaySourceExternal ID
Transcriptional misregulation in cancerKEGGko05202
Transcriptional misregulation in cancerKEGGhsa05202
MicroRNAs in cancerKEGGhsa05206
MicroRNAs in cancerKEGGko05206
Transmembrane transport of small moleculesREACTOMER-HSA-382551
SLC-mediated transmembrane transportREACTOMER-HSA-425407
Hexose transportREACTOMER-HSA-189200
Glucose transportREACTOMER-HSA-70153
MetabolismREACTOMER-HSA-1430728
Metabolism of carbohydratesREACTOMER-HSA-71387

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
191369432009Transcriptome sequencing to detect gene fusions in cancer.346
181722982008Characterization of TMPRSS2:ETV5 and SLC45A3:ETV5 gene fusions in prostate cancer.101
181931842008Ectopic expression of miR-126*, an intronic product of the vascular endothelial EGF-like 7 gene, regulates prostein translation and invasiveness of prostate cancer LNCaP cells.61
227190192012Chimeric transcript generated by cis-splicing of adjacent genes regulates prostate cancer cell proliferation.51
196492102009N-myc downstream regulated gene 1 (NDRG1) is fused to ERG in prostate cancer.44
201189102010Prevalence of TMPRSS2-ERG and SLC45A3-ERG gene fusions in a large prostatectomy cohort.43
177211902007The role of P501S and PSA in the diagnosis of metastatic adenocarcinoma of the prostate.19
151760542004Prostein expression is highly restricted to normal and malignant prostate tissues.15
228217572013Loss of SLC45A3 protein (prostein) expression in prostate cancer is associated with SLC45A3-ERG gene rearrangement and an unfavorable clinical course.10
269388742016Role of CTCF in Regulating SLC45A3-ELK4 Chimeric RNA.9

Citation

Dessen P

SLC45A3 (solute carrier family 45 member 3)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/41657/slc45a3