Atlas of Genetics and Cytogenetics in Oncology and Haematology

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SLC4A3 (solute carrier family 4 member 3)

Identity

Alias_namessolute carrier family 4, anion exchanger, member 3
solute carrier family 4 (anion exchanger), member 3
Alias_symbol (synonym)AE3
SLC2C
Other aliasCAE3/BAE3
HGNC (Hugo) SLC4A3
LocusID (NCBI) 6508
Atlas_Id 73453
Location 2q35  [Link to chromosome band 2q35]
Location_base_pair Starts at 219627570 and ends at 219641980 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)		KAZN (1p36.21) / SLC4A3 (2q35)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)SLC4A3   11029
Cards
Entrez_Gene (NCBI)SLC4A3  6508  solute carrier family 4 member 3
AliasesAE3; CAE3/BAE3; SLC2C
GeneCards (Weizmann)SLC4A3
Ensembl hg19 (Hinxton)ENSG00000114923 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000114923 [Gene_View]  chr2:219627570-219641980 [Contig_View]  SLC4A3 [Vega]
ICGC DataPortalENSG00000114923
TCGA cBioPortalSLC4A3
AceView (NCBI)SLC4A3
Genatlas (Paris)SLC4A3
WikiGenes6508
SOURCE (Princeton)SLC4A3
Genetics Home Reference (NIH)SLC4A3
Genomic and cartography
GoldenPath hg38 (UCSC)SLC4A3  -     chr2:219627570-219641980 +  2q35   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SLC4A3  -     2q35   [Description]    (hg19-Feb_2009)
EnsemblSLC4A3 - 2q35 [CytoView hg19]  SLC4A3 - 2q35 [CytoView hg38]
Mapping of homologs : NCBISLC4A3 [Mapview hg19]  SLC4A3 [Mapview hg38]
OMIM106195   
Gene and transcription
Genbank (Entrez)AK226122 AK289974 AK299109 AK299595 AK309025
RefSeq transcript (Entrez)NM_001326559 NM_005070 NM_201574
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SLC4A3
Cluster EST : UnigeneHs.684906 [ NCBI ]
CGAP (NCI)Hs.684906
Alternative Splicing GalleryENSG00000114923
Gene ExpressionSLC4A3 [ NCBI-GEO ]   SLC4A3 [ EBI - ARRAY_EXPRESS ]   SLC4A3 [ SEEK ]   SLC4A3 [ MEM ]
Gene Expression Viewer (FireBrowse)SLC4A3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6508
GTEX Portal (Tissue expression)SLC4A3
Protein : pattern, domain, 3D structure
UniProt/SwissProtP48751   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP48751  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP48751
Splice isoforms : SwissVarP48751
PhosPhoSitePlusP48751
Domaine pattern : Prosite (Expaxy)ANION_EXCHANGER_1 (PS00219)    ANION_EXCHANGER_2 (PS00220)   
Domains : Interpro (EBI)Anion_exchange    Anion_exchange_3    Anion_exchange_CS    Band3_cytoplasmic_dom    HCO3_transpt_C    HCO3_transpt_euk    PTrfase/Anion_transptr   
Domain families : Pfam (Sanger)Band_3_cyto (PF07565)    HCO3_cotransp (PF00955)   
Domain families : Pfam (NCBI)pfam07565    pfam00955   
Conserved Domain (NCBI)SLC4A3
DMDM Disease mutations6508
Blocks (Seattle)SLC4A3
SuperfamilyP48751
Human Protein AtlasENSG00000114923
Peptide AtlasP48751
HPRD00109
IPIIPI00011159   IPI00473049   IPI00401785   IPI00383471   IPI00478422   IPI00745275   IPI00877865   IPI00877983   IPI00892930   
Protein Interaction databases
DIP (DOE-UCLA)P48751
IntAct (EBI)P48751
FunCoupENSG00000114923
BioGRIDSLC4A3
STRING (EMBL)SLC4A3
ZODIACSLC4A3
Ontologies - Pathways
QuickGOP48751
Ontology : AmiGOinorganic anion exchanger activity  plasma membrane  integral component of plasma membrane  transport  anion transmembrane transporter activity  anion:anion antiporter activity  inorganic anion transport  bicarbonate transport  bicarbonate transport  membrane  regulation of intracellular pH  anion transmembrane transport  
Ontology : EGO-EBIinorganic anion exchanger activity  plasma membrane  integral component of plasma membrane  transport  anion transmembrane transporter activity  anion:anion antiporter activity  inorganic anion transport  bicarbonate transport  bicarbonate transport  membrane  regulation of intracellular pH  anion transmembrane transport  
NDEx NetworkSLC4A3
Atlas of Cancer Signalling NetworkSLC4A3
Wikipedia pathwaysSLC4A3
Orthology - Evolution
OrthoDB6508
GeneTree (enSembl)ENSG00000114923
Phylogenetic Trees/Animal Genes : TreeFamSLC4A3
HOVERGENP48751
HOGENOMP48751
Homologs : HomoloGeneSLC4A3
Homology/Alignments : Family Browser (UCSC)SLC4A3
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSLC4A3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SLC4A3
dbVarSLC4A3
ClinVarSLC4A3
1000_GenomesSLC4A3 
Exome Variant ServerSLC4A3
ExAC (Exome Aggregation Consortium)SLC4A3 (select the gene name)
Genetic variants : HAPMAP6508
Genomic Variants (DGV)SLC4A3 [DGVbeta]
DECIPHERSLC4A3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSLC4A3 
Mutations
ICGC Data PortalSLC4A3 
TCGA Data PortalSLC4A3 
Broad Tumor PortalSLC4A3
OASIS PortalSLC4A3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSLC4A3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSLC4A3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SLC4A3
DgiDB (Drug Gene Interaction Database)SLC4A3
DoCM (Curated mutations)SLC4A3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SLC4A3 (select a term)
intoGenSLC4A3
Cancer3DSLC4A3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM106195   
Orphanet
MedgenSLC4A3
Genetic Testing Registry SLC4A3
NextProtP48751 [Medical]
TSGene6508
GENETestsSLC4A3
Target ValidationSLC4A3
Huge Navigator SLC4A3 [HugePedia]
snp3D : Map Gene to Disease6508
BioCentury BCIQSLC4A3
ClinGenSLC4A3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6508
Chemical/Pharm GKB GenePA35897
Clinical trialSLC4A3
Miscellaneous
canSAR (ICR)SLC4A3 (select the gene name)
Probes
Litterature
PubMed21 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSLC4A3
EVEXSLC4A3
GoPubMedSLC4A3
iHOPSLC4A3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:38:15 CEST 2017
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