Atlas of Genetics and Cytogenetics in Oncology and Haematology


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SLC4A7 (solute carrier family 4 member 7)

Identity

Alias_namesSLC4A6
solute carrier family 4
Alias_symbol (synonym)NBC3
SBC2
Other aliasNBC2
NBCN1
HGNC (Hugo) SLC4A7
LocusID (NCBI) 9497
Atlas_Id 53241
Location 3p24.1  [Link to chromosome band 3p24]
Location_base_pair Starts at 27372721 and ends at 27484420 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ARID4B (1q42.3) / SLC4A7 (3p24.1)CMC1 (3p24.1) / SLC4A7 (3p24.1)CYP4A11 (1p33) / SLC4A7 (3p24.1)
EOMES (3p24.1) / SLC4A7 (3p24.1)SLC4A7 (3p24.1) / SLC4A7 (3p24.1)SLC4A7 (3p24.1) / TYR (11q14.3)
SLC4A7 3p24.1 / TYR 11q14.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  Lung: Translocations in Adenocarcinoma


External links

Nomenclature
HGNC (Hugo)SLC4A7   11033
Cards
Entrez_Gene (NCBI)SLC4A7  9497  solute carrier family 4 member 7
AliasesNBC2; NBC3; NBCN1; SBC2; 
SLC4A6
GeneCards (Weizmann)SLC4A7
Ensembl hg19 (Hinxton)ENSG00000033867 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000033867 [Gene_View]  chr3:27372721-27484420 [Contig_View]  SLC4A7 [Vega]
ICGC DataPortalENSG00000033867
TCGA cBioPortalSLC4A7
AceView (NCBI)SLC4A7
Genatlas (Paris)SLC4A7
WikiGenes9497
SOURCE (Princeton)SLC4A7
Genetics Home Reference (NIH)SLC4A7
Genomic and cartography
GoldenPath hg38 (UCSC)SLC4A7  -     chr3:27372721-27484420 -  3p24.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SLC4A7  -     3p24.1   [Description]    (hg19-Feb_2009)
EnsemblSLC4A7 - 3p24.1 [CytoView hg19]  SLC4A7 - 3p24.1 [CytoView hg38]
Mapping of homologs : NCBISLC4A7 [Mapview hg19]  SLC4A7 [Mapview hg38]
OMIM603353   
Gene and transcription
Genbank (Entrez)AA569234 AB012130 AF047033 AF053755 AF089726
RefSeq transcript (Entrez)NM_001258379 NM_001258380 NM_001321103 NM_001321104 NM_001321105 NM_001321106 NM_001321107 NM_001321108 NM_003615
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SLC4A7
Cluster EST : UnigeneHs.250072 [ NCBI ]
CGAP (NCI)Hs.250072
Alternative Splicing GalleryENSG00000033867
Gene ExpressionSLC4A7 [ NCBI-GEO ]   SLC4A7 [ EBI - ARRAY_EXPRESS ]   SLC4A7 [ SEEK ]   SLC4A7 [ MEM ]
Gene Expression Viewer (FireBrowse)SLC4A7 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9497
GTEX Portal (Tissue expression)SLC4A7
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y6M7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y6M7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y6M7
Splice isoforms : SwissVarQ9Y6M7
PhosPhoSitePlusQ9Y6M7
Domains : Interpro (EBI)Band3_cytoplasmic_dom    HCO3_transpt_C    HCO3_transpt_euk    PTrfase/Anion_transptr   
Domain families : Pfam (Sanger)Band_3_cyto (PF07565)    HCO3_cotransp (PF00955)   
Domain families : Pfam (NCBI)pfam07565    pfam00955   
Conserved Domain (NCBI)SLC4A7
DMDM Disease mutations9497
Blocks (Seattle)SLC4A7
SuperfamilyQ9Y6M7
Human Protein AtlasENSG00000033867
Peptide AtlasQ9Y6M7
HPRD04521
IPIIPI00328342   IPI00387156   IPI00719704   IPI00719757   IPI00021058   IPI00926539   IPI00927034   IPI00926820   IPI00926934   IPI00927188   IPI00927639   IPI00927879   IPI00924711   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y6M7
IntAct (EBI)Q9Y6M7
FunCoupENSG00000033867
BioGRIDSLC4A7
STRING (EMBL)SLC4A7
ZODIACSLC4A7
Ontologies - Pathways
QuickGOQ9Y6M7
Ontology : AmiGOinorganic anion exchanger activity  plasma membrane  integral component of plasma membrane  anion transmembrane transporter activity  sodium:bicarbonate symporter activity  sodium:bicarbonate symporter activity  inorganic anion transport  bicarbonate transport  bicarbonate transport  bicarbonate transport  integral component of membrane  basolateral plasma membrane  apical plasma membrane  cytoplasmic vesicle  stereocilium  sodium ion transmembrane transport  synapse  regulation of intracellular pH  auditory receptor cell development  anion transmembrane transport  
Ontology : EGO-EBIinorganic anion exchanger activity  plasma membrane  integral component of plasma membrane  anion transmembrane transporter activity  sodium:bicarbonate symporter activity  sodium:bicarbonate symporter activity  inorganic anion transport  bicarbonate transport  bicarbonate transport  bicarbonate transport  integral component of membrane  basolateral plasma membrane  apical plasma membrane  cytoplasmic vesicle  stereocilium  sodium ion transmembrane transport  synapse  regulation of intracellular pH  auditory receptor cell development  anion transmembrane transport  
NDEx NetworkSLC4A7
Atlas of Cancer Signalling NetworkSLC4A7
Wikipedia pathwaysSLC4A7
Orthology - Evolution
OrthoDB9497
GeneTree (enSembl)ENSG00000033867
Phylogenetic Trees/Animal Genes : TreeFamSLC4A7
HOVERGENQ9Y6M7
HOGENOMQ9Y6M7
Homologs : HomoloGeneSLC4A7
Homology/Alignments : Family Browser (UCSC)SLC4A7
Gene fusions - Rearrangements
Fusion : MitelmanCMC1/SLC4A7 [3p24.1/3p24.1]  [inv(3)(p24p24)]  
Fusion : MitelmanEOMES/SLC4A7 [3p24.1/3p24.1]  [t(3;3)(p24;p24)]  
Fusion : MitelmanSLC4A7/TYR [3p24.1/11q14.3]  [t(3;11)(p24;q14)]  
Fusion: TCGASLC4A7 3p24.1 TYR 11q14.3 LGG
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSLC4A7 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SLC4A7
dbVarSLC4A7
ClinVarSLC4A7
1000_GenomesSLC4A7 
Exome Variant ServerSLC4A7
ExAC (Exome Aggregation Consortium)SLC4A7 (select the gene name)
Genetic variants : HAPMAP9497
Genomic Variants (DGV)SLC4A7 [DGVbeta]
DECIPHERSLC4A7 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSLC4A7 
Mutations
ICGC Data PortalSLC4A7 
TCGA Data PortalSLC4A7 
Broad Tumor PortalSLC4A7
OASIS PortalSLC4A7 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSLC4A7  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSLC4A7
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
BioMutasearch SLC4A7
DgiDB (Drug Gene Interaction Database)SLC4A7
DoCM (Curated mutations)SLC4A7 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SLC4A7 (select a term)
intoGenSLC4A7
Cancer3DSLC4A7(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603353   
Orphanet
MedgenSLC4A7
Genetic Testing Registry SLC4A7
NextProtQ9Y6M7 [Medical]
TSGene9497
GENETestsSLC4A7
Target ValidationSLC4A7
Huge Navigator SLC4A7 [HugePedia]
snp3D : Map Gene to Disease9497
BioCentury BCIQSLC4A7
ClinGenSLC4A7
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9497
Chemical/Pharm GKB GenePA35899
Clinical trialSLC4A7
Miscellaneous
canSAR (ICR)SLC4A7 (select the gene name)
Probes
Litterature
PubMed39 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSLC4A7
EVEXSLC4A7
GoPubMedSLC4A7
iHOPSLC4A7
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Aug 1 17:14:56 CEST 2017

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