Atlas of Genetics and Cytogenetics in Oncology and Haematology


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SLC5A1 (solute carrier family 5 (sodium/glucose cotransporter), member 1)

Identity

Other namesD22S675
NAGT
SGLT1
HGNC (Hugo) SLC5A1
LocusID (NCBI) 6523
Location 22q12.3
Location_base_pair Starts at 32439019 and ends at 32509011 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)SLC5A1   11036
Cards
Entrez_Gene (NCBI)SLC5A1  6523  solute carrier family 5 (sodium/glucose cotransporter), member 1
GeneCards (Weizmann)SLC5A1
Ensembl (Hinxton)ENSG00000100170 [Gene_View]  chr22:32439019-32509011 [Contig_View]  SLC5A1 [Vega]
ICGC DataPortalENSG00000100170
cBioPortalSLC5A1
AceView (NCBI)SLC5A1
Genatlas (Paris)SLC5A1
WikiGenes6523
SOURCE (Princeton)NM_000343 NM_001256314
Genomic and cartography
GoldenPath (UCSC)SLC5A1  -  22q12.3   chr22:32439019-32509011 +  22q12.3   [Description]    (hg19-Feb_2009)
EnsemblSLC5A1 - 22q12.3 [CytoView]
Mapping of homologs : NCBISLC5A1 [Mapview]
OMIM182380   606824   
Gene and transcription
Genbank (Entrez)AI078794 AK297665 AK312948 AK316184 BC139838
RefSeq transcript (Entrez)NM_000343 NM_001256314
RefSeq genomic (Entrez)AC_000154 NC_000022 NC_018933 NG_017045 NT_011520 NW_001838745 NW_004929430
Consensus coding sequences : CCDS (NCBI)SLC5A1
Cluster EST : UnigeneHs.1964 [ NCBI ]
CGAP (NCI)Hs.1964
Alternative Splicing : Fast-db (Paris)GSHG0019966
Alternative Splicing GalleryENSG00000100170
Gene ExpressionSLC5A1 [ NCBI-GEO ]     SLC5A1 [ SEEK ]   SLC5A1 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP13866 (Uniprot)
NextProtP13866  [Medical]
With graphics : InterProP13866
Splice isoforms : SwissVarP13866 (Swissvar)
Domaine pattern : Prosite (Expaxy)NA_SOLUT_SYMP_1 (PS00456)    NA_SOLUT_SYMP_2 (PS00457)    NA_SOLUT_SYMP_3 (PS50283)   
Domains : Interpro (EBI)Na/solute_symporter [organisation]   Na/solute_symporter_CS [organisation]   Na/solute_symporter_subgr [organisation]  
Related proteins : CluSTrP13866
Domain families : Pfam (Sanger)SSF (PF00474)   
Domain families : Pfam (NCBI)pfam00474   
DMDM Disease mutations6523
Blocks (Seattle)P13866
Human Protein AtlasENSG00000100170 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasP13866
HPRD01668
IPIIPI00010866   IPI01015369   
Protein Interaction databases
DIP (DOE-UCLA)P13866
IntAct (EBI)P13866
FunCoupENSG00000100170
BioGRIDSLC5A1
InParanoidP13866
Interologous Interaction database P13866
IntegromeDBSLC5A1
STRING (EMBL)SLC5A1
Ontologies - Pathways
Ontology : AmiGOglucose:sodium symporter activity  protein binding  plasma membrane  integral component of plasma membrane  cell-cell junction  carbohydrate metabolic process  sodium ion transport  hexose transport  glucose transport  apical plasma membrane  brush border membrane  small molecule metabolic process  intestinal absorption  transmembrane transport  extracellular vesicular exosome  
Ontology : EGO-EBIglucose:sodium symporter activity  protein binding  plasma membrane  integral component of plasma membrane  cell-cell junction  carbohydrate metabolic process  sodium ion transport  hexose transport  glucose transport  apical plasma membrane  brush border membrane  small molecule metabolic process  intestinal absorption  transmembrane transport  extracellular vesicular exosome  
Pathways : KEGGCarbohydrate digestion and absorption    Bile secretion    Mineral absorption   
Protein Interaction DatabaseSLC5A1
Wikipedia pathwaysSLC5A1
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)SLC5A1
snp3D : Map Gene to Disease6523
SNP (GeneSNP Utah)SLC5A1
SNP : HGBaseSLC5A1
Genetic variants : HAPMAPSLC5A1
Exome VariantSLC5A1
1000_GenomesSLC5A1 
ICGC programENSG00000100170 
Somatic Mutations in Cancer : COSMICSLC5A1 
CONAN: Copy Number AnalysisSLC5A1 
Mutations and Diseases : HGMDSLC5A1
Genomic VariantsSLC5A1  SLC5A1 [DGVbeta]
dbVarSLC5A1
ClinVarSLC5A1
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM182380    606824   
MedgenSLC5A1
GENETestsSLC5A1
Disease Genetic AssociationSLC5A1
Huge Navigator SLC5A1 [HugePedia]  SLC5A1 [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneSLC5A1
Homology/Alignments : Family Browser (UCSC)SLC5A1
Phylogenetic Trees/Animal Genes : TreeFamSLC5A1
Chemical/Protein Interactions : CTD6523
Chemical/Pharm GKB GenePA308
Clinical trialSLC5A1
Cancer Resource (Charite)ENSG00000100170
Other databases
Probes
Litterature
PubMed78 Pubmed reference(s) in Entrez
CoreMineSLC5A1
iHOPSLC5A1
OncoSearchSLC5A1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jul 30 14:16:08 CEST 2014

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