SLC5A10 (solute carrier family 5 member 10)

2019-04-01 Affiliation

Identity

HGNC

SLC5A10

LOCATION

17p11.2

LOCUSID

125206

ALIAS

SGLT-5,SGLT5

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 125206
MIM: 618636
HGNC: 23155
Ensembl: ENSG00000154025

Variants:

dbSNP: 125206
ClinVar: 125206
TCGA: ENSG00000154025
COSMIC: SLC5A10

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000154025	ENST00000317977	A0PJK1
ENSG00000154025	ENST00000395643	A0PJK1
ENSG00000154025	ENST00000395645	A0PJK1
ENSG00000154025	ENST00000395647	A0PJK1
ENSG00000154025	ENST00000417251	A0PJK1

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Transmembrane transport of small molecules	REACTOME	R-HSA-382551
SLC-mediated transmembrane transport	REACTOME	R-HSA-425407
Hexose transport	REACTOME	R-HSA-189200
Metabolism	REACTOME	R-HSA-1430728
Metabolism of carbohydrates	REACTOME	R-HSA-71387

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
19913121	2009	Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.	85
22212718	2012	Functional characterisation of human SGLT-5 as a novel kidney-specific sodium-dependent sugar transporter.	17
20628086	2010	Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.	11
30281872	2018	Functional intronic variant of SLC5A10 affects DRG2 expression and survival outcomes of early-stage non-small-cell lung cancer.	3
24573086	2014	Fingerprints of hSGLT5 sugar and cation selectivity.	0

Citation

Dessen P

SLC5A10 (solute carrier family 5 member 10)

Atlas Genet Cytogenet Oncol Haematol. 2019-04-01

Online version: http://atlasgeneticsoncology.org/gene/57810/slc5a10