SLC5A11 (solute carrier family 5 member 11)

2014-11-01  

Identity

HGNC
SLC5A11
LOCATION
16p12.1
LOCUSID
115584
ALIAS
KST1,RKST1,SGLT6,SMIT2
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 115584
MIM: 610238
HGNC: 23091
Ensembl: ENSG00000158865

Variants:

dbSNP: 115584
ClinVar: 115584
TCGA: ENSG00000158865
COSMIC: SLC5A11

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000158865ENST00000347898Q8WWX8
ENSG00000158865ENST00000424767Q8WWX8
ENSG00000158865ENST00000449109Q8WWX8
ENSG00000158865ENST00000488922I3L1G0
ENSG00000158865ENST00000545376Q8WWX8
ENSG00000158865ENST00000565769Q8WWX8
ENSG00000158865ENST00000567758Q8WWX8
ENSG00000158865ENST00000568579Q8WWX8
ENSG00000158865ENST00000569071Q8WWX8
ENSG00000158865ENST00000569520H3BN85

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Transmembrane transport of small moleculesREACTOMER-HSA-382551
SLC-mediated transmembrane transportREACTOMER-HSA-425407
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compoundsREACTOMER-HSA-425366
Inositol transportersREACTOMER-HSA-429593

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
208006032010Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study.12
180699352008The sodium-dependent glucose cotransporter SLC5A11 as an autoimmune modifier gene in SLE.10
180699352008The sodium-dependent glucose cotransporter SLC5A11 as an autoimmune modifier gene in SLE.10

Citation

Dessen P

SLC5A11 (solute carrier family 5 member 11)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/73462/slc5a11