Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

SLC5A12 (solute carrier family 5 member 12)

Identity

Alias_namessolute carrier family 5 (sodium/glucose cotransporter), member 12
solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12
Alias_symbol (synonym)MGC52019
SMCT2
Other alias
HGNC (Hugo) SLC5A12
LocusID (NCBI) 159963
Atlas_Id 73463
Location 11p14.2  [Link to chromosome band 11p14]
Location_base_pair Starts at 26667019 and ends at 26722027 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SLC5A12   28750
Cards
Entrez_Gene (NCBI)SLC5A12  159963  solute carrier family 5 member 12
AliasesSMCT2
GeneCards (Weizmann)SLC5A12
Ensembl hg19 (Hinxton)ENSG00000148942 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000148942 [Gene_View]  chr11:26667019-26722027 [Contig_View]  SLC5A12 [Vega]
ICGC DataPortalENSG00000148942
TCGA cBioPortalSLC5A12
AceView (NCBI)SLC5A12
Genatlas (Paris)SLC5A12
WikiGenes159963
SOURCE (Princeton)SLC5A12
Genetics Home Reference (NIH)SLC5A12
Genomic and cartography
GoldenPath hg38 (UCSC)SLC5A12  -     chr11:26667019-26722027 -  11p14.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SLC5A12  -     11p14.2   [Description]    (hg19-Feb_2009)
EnsemblSLC5A12 - 11p14.2 [CytoView hg19]  SLC5A12 - 11p14.2 [CytoView hg38]
Mapping of homologs : NCBISLC5A12 [Mapview hg19]  SLC5A12 [Mapview hg38]
OMIM612455   
Gene and transcription
Genbank (Entrez)AL049270 AW614338 AY299482 BC029048 BC041454
RefSeq transcript (Entrez)NM_178498
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SLC5A12
Cluster EST : UnigeneHs.148907 [ NCBI ]
CGAP (NCI)Hs.148907
Alternative Splicing GalleryENSG00000148942
Gene ExpressionSLC5A12 [ NCBI-GEO ]   SLC5A12 [ EBI - ARRAY_EXPRESS ]   SLC5A12 [ SEEK ]   SLC5A12 [ MEM ]
Gene Expression Viewer (FireBrowse)SLC5A12 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)159963
GTEX Portal (Tissue expression)SLC5A12
Human Protein AtlasENSG00000148942-SLC5A12 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ1EHB4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ1EHB4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ1EHB4
Splice isoforms : SwissVarQ1EHB4
PhosPhoSitePlusQ1EHB4
Domaine pattern : Prosite (Expaxy)NA_SOLUT_SYMP_3 (PS50283)   
Domains : Interpro (EBI)Na/solute_symporter   
Domain families : Pfam (Sanger)SSF (PF00474)   
Domain families : Pfam (NCBI)pfam00474   
Conserved Domain (NCBI)SLC5A12
DMDM Disease mutations159963
Blocks (Seattle)SLC5A12
SuperfamilyQ1EHB4
Human Protein Atlas [tissue]ENSG00000148942-SLC5A12 [tissue]
Peptide AtlasQ1EHB4
HPRD15395
IPIIPI00760881   IPI00328700   IPI00984715   IPI00981441   
Protein Interaction databases
DIP (DOE-UCLA)Q1EHB4
IntAct (EBI)Q1EHB4
FunCoupENSG00000148942
BioGRIDSLC5A12
STRING (EMBL)SLC5A12
ZODIACSLC5A12
Ontologies - Pathways
QuickGOQ1EHB4
Ontology : AmiGOorganic acid:sodium symporter activity  plasma membrane  ion transport  sodium ion transport  lactate transmembrane transporter activity  integral component of membrane  apical plasma membrane  lactate transmembrane transport  extracellular exosome  
Ontology : EGO-EBIorganic acid:sodium symporter activity  plasma membrane  ion transport  sodium ion transport  lactate transmembrane transporter activity  integral component of membrane  apical plasma membrane  lactate transmembrane transport  extracellular exosome  
NDEx NetworkSLC5A12
Atlas of Cancer Signalling NetworkSLC5A12
Wikipedia pathwaysSLC5A12
Orthology - Evolution
OrthoDB159963
GeneTree (enSembl)ENSG00000148942
Phylogenetic Trees/Animal Genes : TreeFamSLC5A12
HOVERGENQ1EHB4
HOGENOMQ1EHB4
Homologs : HomoloGeneSLC5A12
Homology/Alignments : Family Browser (UCSC)SLC5A12
Gene fusions - Rearrangements
Tumor Fusion PortalSLC5A12
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSLC5A12 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SLC5A12
dbVarSLC5A12
ClinVarSLC5A12
1000_GenomesSLC5A12 
Exome Variant ServerSLC5A12
ExAC (Exome Aggregation Consortium)ENSG00000148942
GNOMAD BrowserENSG00000148942
Genetic variants : HAPMAP159963
Genomic Variants (DGV)SLC5A12 [DGVbeta]
DECIPHERSLC5A12 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSLC5A12 
Mutations
ICGC Data PortalSLC5A12 
TCGA Data PortalSLC5A12 
Broad Tumor PortalSLC5A12
OASIS PortalSLC5A12 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSLC5A12  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSLC5A12
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SLC5A12
DgiDB (Drug Gene Interaction Database)SLC5A12
DoCM (Curated mutations)SLC5A12 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SLC5A12 (select a term)
intoGenSLC5A12
Cancer3DSLC5A12(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612455   
Orphanet
DisGeNETSLC5A12
MedgenSLC5A12
Genetic Testing Registry SLC5A12
NextProtQ1EHB4 [Medical]
TSGene159963
GENETestsSLC5A12
Target ValidationSLC5A12
Huge Navigator SLC5A12 [HugePedia]
snp3D : Map Gene to Disease159963
BioCentury BCIQSLC5A12
ClinGenSLC5A12
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD159963
Chemical/Pharm GKB GenePA134873929
Clinical trialSLC5A12
Miscellaneous
canSAR (ICR)SLC5A12 (select the gene name)
Probes
Litterature
PubMed5 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSLC5A12
EVEXSLC5A12
GoPubMedSLC5A12
iHOPSLC5A12
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 13:25:13 CET 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.