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SLC5A3 (solute carrier family 5 member 3)

Identity

Alias_namessolute carrier family 5 (inositol transporter), member 3
solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
Alias_symbol (synonym)SMIT
SMIT1
Other aliasBCW2
SMIT2
HGNC (Hugo) SLC5A3
LocusID (NCBI) 6526
Atlas_Id 45558
Location 21q22.11  [Link to chromosome band 21q22]
Location_base_pair Starts at 34073523 and ends at 34106262 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
SLC5A3 (21q22.11) / UBXN11 (1p36.11)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SLC5A3   11038
Cards
Entrez_Gene (NCBI)SLC5A3  6526  solute carrier family 5 member 3
AliasesBCW2; SMIT; SMIT1; SMIT2
GeneCards (Weizmann)SLC5A3
Ensembl hg19 (Hinxton)ENSG00000198743 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000198743 [Gene_View]  chr21:34073523-34106262 [Contig_View]  SLC5A3 [Vega]
ICGC DataPortalENSG00000198743
TCGA cBioPortalSLC5A3
AceView (NCBI)SLC5A3
Genatlas (Paris)SLC5A3
WikiGenes6526
SOURCE (Princeton)SLC5A3
Genetics Home Reference (NIH)SLC5A3
Genomic and cartography
GoldenPath hg38 (UCSC)SLC5A3  -     chr21:34073523-34106262 +  21q22.11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SLC5A3  -     21q22.11   [Description]    (hg19-Feb_2009)
EnsemblSLC5A3 - 21q22.11 [CytoView hg19]  SLC5A3 - 21q22.11 [CytoView hg38]
Mapping of homologs : NCBISLC5A3 [Mapview hg19]  SLC5A3 [Mapview hg38]
OMIM600444   
Gene and transcription
Genbank (Entrez)AB074183 AK024896 AK026169 AK055913 AK092248
RefSeq transcript (Entrez)NM_006933
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SLC5A3
Cluster EST : UnigeneHs.302742 [ NCBI ]
CGAP (NCI)Hs.302742
Alternative Splicing GalleryENSG00000198743
Gene ExpressionSLC5A3 [ NCBI-GEO ]   SLC5A3 [ EBI - ARRAY_EXPRESS ]   SLC5A3 [ SEEK ]   SLC5A3 [ MEM ]
Gene Expression Viewer (FireBrowse)SLC5A3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6526
GTEX Portal (Tissue expression)SLC5A3
Protein : pattern, domain, 3D structure
UniProt/SwissProtP53794   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP53794  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP53794
Splice isoforms : SwissVarP53794
PhosPhoSitePlusP53794
Domaine pattern : Prosite (Expaxy)NA_SOLUT_SYMP_1 (PS00456)    NA_SOLUT_SYMP_2 (PS00457)    NA_SOLUT_SYMP_3 (PS50283)   
Domains : Interpro (EBI)Na/solute_symporter    Na/solute_symporter_CS   
Domain families : Pfam (Sanger)SSF (PF00474)   
Domain families : Pfam (NCBI)pfam00474   
Conserved Domain (NCBI)SLC5A3
DMDM Disease mutations6526
Blocks (Seattle)SLC5A3
SuperfamilyP53794
Human Protein AtlasENSG00000198743
Peptide AtlasP53794
HPRD02708
IPIIPI00296311   
Protein Interaction databases
DIP (DOE-UCLA)P53794
IntAct (EBI)P53794
FunCoupENSG00000198743
BioGRIDSLC5A3
STRING (EMBL)SLC5A3
ZODIACSLC5A3
Ontologies - Pathways
QuickGOP53794
Ontology : AmiGOmyo-inositol:sodium symporter activity  plasma membrane  integral component of plasma membrane  inositol metabolic process  transport  sodium ion transport  peripheral nervous system development  symporter activity  myo-inositol transport  integral component of membrane  regulation of respiratory gaseous exchange  transmembrane transport  
Ontology : EGO-EBImyo-inositol:sodium symporter activity  plasma membrane  integral component of plasma membrane  inositol metabolic process  transport  sodium ion transport  peripheral nervous system development  symporter activity  myo-inositol transport  integral component of membrane  regulation of respiratory gaseous exchange  transmembrane transport  
NDEx NetworkSLC5A3
Atlas of Cancer Signalling NetworkSLC5A3
Wikipedia pathwaysSLC5A3
Orthology - Evolution
OrthoDB6526
GeneTree (enSembl)ENSG00000198743
Phylogenetic Trees/Animal Genes : TreeFamSLC5A3
HOVERGENP53794
HOGENOMP53794
Homologs : HomoloGeneSLC5A3
Homology/Alignments : Family Browser (UCSC)SLC5A3
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSLC5A3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SLC5A3
dbVarSLC5A3
ClinVarSLC5A3
1000_GenomesSLC5A3 
Exome Variant ServerSLC5A3
ExAC (Exome Aggregation Consortium)SLC5A3 (select the gene name)
Genetic variants : HAPMAP6526
Genomic Variants (DGV)SLC5A3 [DGVbeta]
DECIPHERSLC5A3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSLC5A3 
Mutations
ICGC Data PortalSLC5A3 
TCGA Data PortalSLC5A3 
Broad Tumor PortalSLC5A3
OASIS PortalSLC5A3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSLC5A3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSLC5A3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SLC5A3
DgiDB (Drug Gene Interaction Database)SLC5A3
DoCM (Curated mutations)SLC5A3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SLC5A3 (select a term)
intoGenSLC5A3
Cancer3DSLC5A3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600444   
Orphanet
MedgenSLC5A3
Genetic Testing Registry SLC5A3
NextProtP53794 [Medical]
TSGene6526
GENETestsSLC5A3
Huge Navigator SLC5A3 [HugePedia]
snp3D : Map Gene to Disease6526
BioCentury BCIQSLC5A3
ClinGenSLC5A3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6526
Chemical/Pharm GKB GenePA35903
Clinical trialSLC5A3
Miscellaneous
canSAR (ICR)SLC5A3 (select the gene name)
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSLC5A3
EVEXSLC5A3
GoPubMedSLC5A3
iHOPSLC5A3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:37:54 CEST 2017

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