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SLC5A6 (solute carrier family 5 member 6)

Identity

Alias_namessolute carrier family 5 (sodium-dependent vitamin transporter), member 6
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
Alias_symbol (synonym)SMVT
Other alias
HGNC (Hugo) SLC5A6
LocusID (NCBI) 8884
Atlas_Id 53168
Location 2p23.3  [Link to chromosome band 2p23]
Location_base_pair Starts at 27199587 and ends at 27212307 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
COX17 (3q13.33) / SLC5A6 (2p23.3)RAB11B (19p13.2) / SLC5A6 (2p23.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SLC5A6   11041
Cards
Entrez_Gene (NCBI)SLC5A6  8884  solute carrier family 5 member 6
AliasesSMVT
GeneCards (Weizmann)SLC5A6
Ensembl hg19 (Hinxton)ENSG00000138074 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000138074 [Gene_View]  chr2:27199587-27212307 [Contig_View]  SLC5A6 [Vega]
ICGC DataPortalENSG00000138074
TCGA cBioPortalSLC5A6
AceView (NCBI)SLC5A6
Genatlas (Paris)SLC5A6
WikiGenes8884
SOURCE (Princeton)SLC5A6
Genetics Home Reference (NIH)SLC5A6
Genomic and cartography
GoldenPath hg38 (UCSC)SLC5A6  -     chr2:27199587-27212307 -  2p23.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SLC5A6  -     2p23.3   [Description]    (hg19-Feb_2009)
EnsemblSLC5A6 - 2p23.3 [CytoView hg19]  SLC5A6 - 2p23.3 [CytoView hg38]
Mapping of homologs : NCBISLC5A6 [Mapview hg19]  SLC5A6 [Mapview hg38]
OMIM604024   
Gene and transcription
Genbank (Entrez)AF069307 AF081571 AF288781 AF442149 AF442150
RefSeq transcript (Entrez)NM_021095
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SLC5A6
Cluster EST : UnigeneHs.435735 [ NCBI ]
CGAP (NCI)Hs.435735
Alternative Splicing GalleryENSG00000138074
Gene ExpressionSLC5A6 [ NCBI-GEO ]   SLC5A6 [ EBI - ARRAY_EXPRESS ]   SLC5A6 [ SEEK ]   SLC5A6 [ MEM ]
Gene Expression Viewer (FireBrowse)SLC5A6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8884
GTEX Portal (Tissue expression)SLC5A6
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y289   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y289  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y289
Splice isoforms : SwissVarQ9Y289
PhosPhoSitePlusQ9Y289
Domaine pattern : Prosite (Expaxy)NA_SOLUT_SYMP_1 (PS00456)    NA_SOLUT_SYMP_3 (PS50283)   
Domains : Interpro (EBI)Na/solute_symporter    Na/solute_symporter_CS   
Domain families : Pfam (Sanger)SSF (PF00474)   
Domain families : Pfam (NCBI)pfam00474   
Conserved Domain (NCBI)SLC5A6
DMDM Disease mutations8884
Blocks (Seattle)SLC5A6
SuperfamilyQ9Y289
Human Protein AtlasENSG00000138074
Peptide AtlasQ9Y289
HPRD04934
IPIIPI00031822   IPI00893063   IPI00893811   IPI01013152   IPI00893768   IPI01018113   IPI00894560   IPI00894438   IPI00894242   IPI00894129   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y289
IntAct (EBI)Q9Y289
FunCoupENSG00000138074
BioGRIDSLC5A6
STRING (EMBL)SLC5A6
ZODIACSLC5A6
Ontologies - Pathways
QuickGOQ9Y289
Ontology : AmiGOplasma membrane  integral component of plasma membrane  biotin metabolic process  transport  sodium ion transport  sodium-dependent multivitamin transmembrane transporter activity  vesicle membrane  biotin transport  pantothenate transmembrane transport  pantothenate metabolic process  membrane  brush border membrane  transmembrane transport  
Ontology : EGO-EBIplasma membrane  integral component of plasma membrane  biotin metabolic process  transport  sodium ion transport  sodium-dependent multivitamin transmembrane transporter activity  vesicle membrane  biotin transport  pantothenate transmembrane transport  pantothenate metabolic process  membrane  brush border membrane  transmembrane transport  
Pathways : KEGGVitamin digestion and absorption   
NDEx NetworkSLC5A6
Atlas of Cancer Signalling NetworkSLC5A6
Wikipedia pathwaysSLC5A6
Orthology - Evolution
OrthoDB8884
GeneTree (enSembl)ENSG00000138074
Phylogenetic Trees/Animal Genes : TreeFamSLC5A6
HOVERGENQ9Y289
HOGENOMQ9Y289
Homologs : HomoloGeneSLC5A6
Homology/Alignments : Family Browser (UCSC)SLC5A6
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSLC5A6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SLC5A6
dbVarSLC5A6
ClinVarSLC5A6
1000_GenomesSLC5A6 
Exome Variant ServerSLC5A6
ExAC (Exome Aggregation Consortium)SLC5A6 (select the gene name)
Genetic variants : HAPMAP8884
Genomic Variants (DGV)SLC5A6 [DGVbeta]
DECIPHERSLC5A6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSLC5A6 
Mutations
ICGC Data PortalSLC5A6 
TCGA Data PortalSLC5A6 
Broad Tumor PortalSLC5A6
OASIS PortalSLC5A6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSLC5A6  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSLC5A6
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SLC5A6
DgiDB (Drug Gene Interaction Database)SLC5A6
DoCM (Curated mutations)SLC5A6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SLC5A6 (select a term)
intoGenSLC5A6
Cancer3DSLC5A6(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604024   
Orphanet
MedgenSLC5A6
Genetic Testing Registry SLC5A6
NextProtQ9Y289 [Medical]
TSGene8884
GENETestsSLC5A6
Target ValidationSLC5A6
Huge Navigator SLC5A6 [HugePedia]
snp3D : Map Gene to Disease8884
BioCentury BCIQSLC5A6
ClinGenSLC5A6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8884
Chemical/Pharm GKB GenePA379
Clinical trialSLC5A6
Miscellaneous
canSAR (ICR)SLC5A6 (select the gene name)
Probes
Litterature
PubMed34 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSLC5A6
EVEXSLC5A6
GoPubMedSLC5A6
iHOPSLC5A6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:56:15 CEST 2017

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