Atlas of Genetics and Cytogenetics in Oncology and Haematology


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SLC6A11 (solute carrier family 6 member 11)

Identity

Alias_namessolute carrier family 6 (neurotransmitter transporter, GABA), member 11
solute carrier family 6 (neurotransmitter transporter), member 11
Alias_symbol (synonym)GAT3
Other aliasGAT-3
GAT4
HGNC (Hugo) SLC6A11
LocusID (NCBI) 6538
Atlas_Id 73468
Location 3p25.3  [Link to chromosome band 3p25]
Location_base_pair Starts at 10816200 and ends at 10833792 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SLC6A11   11044
Cards
Entrez_Gene (NCBI)SLC6A11  6538  solute carrier family 6 member 11
AliasesGAT-3; GAT3; GAT4
GeneCards (Weizmann)SLC6A11
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]  chr3:10816200-10833792 [Contig_View]  SLC6A11 [Vega]
TCGA cBioPortalSLC6A11
AceView (NCBI)SLC6A11
Genatlas (Paris)SLC6A11
WikiGenes6538
SOURCE (Princeton)SLC6A11
Genetics Home Reference (NIH)SLC6A11
Genomic and cartography
GoldenPath hg38 (UCSC)SLC6A11  -     chr3:10816200-10833792 +  3p25.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SLC6A11  -     3p25.3   [Description]    (hg19-Feb_2009)
EnsemblSLC6A11 - 3p25.3 [CytoView hg19]  SLC6A11 - 3p25.3 [CytoView hg38]
Mapping of homologs : NCBISLC6A11 [Mapview hg19]  SLC6A11 [Mapview hg38]
OMIM607952   
Gene and transcription
Genbank (Entrez)AK055416 AK312719 BC036083 BC152735 S75989
RefSeq transcript (Entrez)NM_001317406 NM_014229
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SLC6A11
Cluster EST : UnigeneHs.657405 [ NCBI ]
CGAP (NCI)Hs.657405
Gene ExpressionSLC6A11 [ NCBI-GEO ]   SLC6A11 [ EBI - ARRAY_EXPRESS ]   SLC6A11 [ SEEK ]   SLC6A11 [ MEM ]
Gene Expression Viewer (FireBrowse)SLC6A11 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6538
GTEX Portal (Tissue expression)SLC6A11
Protein : pattern, domain, 3D structure
UniProt/SwissProtP48066   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP48066  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP48066
Splice isoforms : SwissVarP48066
PhosPhoSitePlusP48066
Domaine pattern : Prosite (Expaxy)NA_NEUROTRAN_SYMP_1 (PS00610)    NA_NEUROTRAN_SYMP_2 (PS00754)    NA_NEUROTRAN_SYMP_3 (PS50267)   
Domains : Interpro (EBI)Na/ntran_symport    Na/ntran_symport_GABA_GAT3   
Domain families : Pfam (Sanger)SNF (PF00209)   
Domain families : Pfam (NCBI)pfam00209   
Conserved Domain (NCBI)SLC6A11
DMDM Disease mutations6538
Blocks (Seattle)SLC6A11
SuperfamilyP48066
Peptide AtlasP48066
HPRD06406
IPIIPI00007648   IPI00479462   
Protein Interaction databases
DIP (DOE-UCLA)P48066
IntAct (EBI)P48066
BioGRIDSLC6A11
STRING (EMBL)SLC6A11
ZODIACSLC6A11
Ontologies - Pathways
QuickGOP48066
Ontology : AmiGOtransporter activity  neurotransmitter:sodium symporter activity  gamma-aminobutyric acid:sodium symporter activity  cytoplasm  plasma membrane  integral component of plasma membrane  transport  neurotransmitter transport  brain development  gamma-aminobutyric acid transport  integral component of membrane  neurotransmitter binding  response to drug  cell projection  transmembrane transport  
Ontology : EGO-EBItransporter activity  neurotransmitter:sodium symporter activity  gamma-aminobutyric acid:sodium symporter activity  cytoplasm  plasma membrane  integral component of plasma membrane  transport  neurotransmitter transport  brain development  gamma-aminobutyric acid transport  integral component of membrane  neurotransmitter binding  response to drug  cell projection  transmembrane transport  
Pathways : KEGGGABAergic synapse   
NDEx NetworkSLC6A11
Atlas of Cancer Signalling NetworkSLC6A11
Wikipedia pathwaysSLC6A11
Orthology - Evolution
OrthoDB6538
Phylogenetic Trees/Animal Genes : TreeFamSLC6A11
HOVERGENP48066
HOGENOMP48066
Homologs : HomoloGeneSLC6A11
Homology/Alignments : Family Browser (UCSC)SLC6A11
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSLC6A11 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SLC6A11
dbVarSLC6A11
ClinVarSLC6A11
1000_GenomesSLC6A11 
Exome Variant ServerSLC6A11
ExAC (Exome Aggregation Consortium)SLC6A11 (select the gene name)
Genetic variants : HAPMAP6538
Genomic Variants (DGV)SLC6A11 [DGVbeta]
DECIPHERSLC6A11 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSLC6A11 
Mutations
ICGC Data PortalSLC6A11 
TCGA Data PortalSLC6A11 
Broad Tumor PortalSLC6A11
OASIS PortalSLC6A11 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSLC6A11  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSLC6A11
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SLC6A11
DgiDB (Drug Gene Interaction Database)SLC6A11
DoCM (Curated mutations)SLC6A11 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SLC6A11 (select a term)
intoGenSLC6A11
Cancer3DSLC6A11(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607952   
Orphanet
MedgenSLC6A11
Genetic Testing Registry SLC6A11
NextProtP48066 [Medical]
TSGene6538
GENETestsSLC6A11
Target ValidationSLC6A11
Huge Navigator SLC6A11 [HugePedia]
snp3D : Map Gene to Disease6538
BioCentury BCIQSLC6A11
ClinGenSLC6A11
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6538
Chemical/Pharm GKB GenePA35907
Clinical trialSLC6A11
Miscellaneous
canSAR (ICR)SLC6A11 (select the gene name)
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSLC6A11
EVEXSLC6A11
GoPubMedSLC6A11
iHOPSLC6A11
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:38:17 CEST 2017

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