Atlas of Genetics and Cytogenetics in Oncology and Haematology


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SLC6A5 (solute carrier family 6 member 5)

Identity

Alias_namesNET1
solute carrier family 6 (neurotransmitter transporter, glycine), member 5
solute carrier family 6 (neurotransmitter transporter), member 5
Alias_symbol (synonym)GLYT2
Other aliasGLYT-2
HKPX3
HGNC (Hugo) SLC6A5
LocusID (NCBI) 9152
Atlas_Id 73477
Location 11p15.1  [Link to chromosome band 11p15]
Location_base_pair Starts at 20599400 and ends at 20655064 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
NELL1 (11p15.1) / SLC6A5 (11p15.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SLC6A5   11051
Cards
Entrez_Gene (NCBI)SLC6A5  9152  solute carrier family 6 member 5
AliasesGLYT-2; GLYT2; HKPX3; NET1
GeneCards (Weizmann)SLC6A5
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]  chr11:20599400-20655064 [Contig_View]  SLC6A5 [Vega]
TCGA cBioPortalSLC6A5
AceView (NCBI)SLC6A5
Genatlas (Paris)SLC6A5
WikiGenes9152
SOURCE (Princeton)SLC6A5
Genetics Home Reference (NIH)SLC6A5
Genomic and cartography
GoldenPath hg38 (UCSC)SLC6A5  -     chr11:20599400-20655064 +  11p15.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SLC6A5  -     11p15.1   [Description]    (hg19-Feb_2009)
EnsemblSLC6A5 - 11p15.1 [CytoView hg19]  SLC6A5 - 11p15.1 [CytoView hg38]
Mapping of homologs : NCBISLC6A5 [Mapview hg19]  SLC6A5 [Mapview hg38]
OMIM604159   614618   
Gene and transcription
Genbank (Entrez)AA625644 AF085412 AF117999 AF142501 AF352733
RefSeq transcript (Entrez)NM_001318369 NM_004211
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SLC6A5
Cluster EST : UnigeneHs.136557 [ NCBI ]
CGAP (NCI)Hs.136557
Gene ExpressionSLC6A5 [ NCBI-GEO ]   SLC6A5 [ EBI - ARRAY_EXPRESS ]   SLC6A5 [ SEEK ]   SLC6A5 [ MEM ]
Gene Expression Viewer (FireBrowse)SLC6A5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9152
GTEX Portal (Tissue expression)SLC6A5
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y345   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y345  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y345
Splice isoforms : SwissVarQ9Y345
PhosPhoSitePlusQ9Y345
Domaine pattern : Prosite (Expaxy)NA_NEUROTRAN_SYMP_1 (PS00610)    NA_NEUROTRAN_SYMP_2 (PS00754)    NA_NEUROTRAN_SYMP_3 (PS50267)   
Domains : Interpro (EBI)Na/ntran_symport   
Domain families : Pfam (Sanger)SNF (PF00209)   
Domain families : Pfam (NCBI)pfam00209   
Conserved Domain (NCBI)SLC6A5
DMDM Disease mutations9152
Blocks (Seattle)SLC6A5
SuperfamilyQ9Y345
Peptide AtlasQ9Y345
HPRD08378
IPIIPI00003484   IPI00979971   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y345
IntAct (EBI)Q9Y345
BioGRIDSLC6A5
STRING (EMBL)SLC6A5
ZODIACSLC6A5
Ontologies - Pathways
QuickGOQ9Y345
Ontology : AmiGOneurotransmitter:sodium symporter activity  plasma membrane  plasma membrane  integral component of plasma membrane  transport  neurotransmitter transport  chemical synaptic transmission  glycine:sodium symporter activity  glycine:sodium symporter activity  integral component of membrane  glycine import  metal ion binding  transmembrane transport  synaptic transmission, glycinergic  
Ontology : EGO-EBIneurotransmitter:sodium symporter activity  plasma membrane  plasma membrane  integral component of plasma membrane  transport  neurotransmitter transport  chemical synaptic transmission  glycine:sodium symporter activity  glycine:sodium symporter activity  integral component of membrane  glycine import  metal ion binding  transmembrane transport  synaptic transmission, glycinergic  
NDEx NetworkSLC6A5
Atlas of Cancer Signalling NetworkSLC6A5
Wikipedia pathwaysSLC6A5
Orthology - Evolution
OrthoDB9152
Phylogenetic Trees/Animal Genes : TreeFamSLC6A5
HOVERGENQ9Y345
HOGENOMQ9Y345
Homologs : HomoloGeneSLC6A5
Homology/Alignments : Family Browser (UCSC)SLC6A5
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSLC6A5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SLC6A5
dbVarSLC6A5
ClinVarSLC6A5
1000_GenomesSLC6A5 
Exome Variant ServerSLC6A5
ExAC (Exome Aggregation Consortium)SLC6A5 (select the gene name)
Genetic variants : HAPMAP9152
Genomic Variants (DGV)SLC6A5 [DGVbeta]
DECIPHERSLC6A5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSLC6A5 
Mutations
ICGC Data PortalSLC6A5 
TCGA Data PortalSLC6A5 
Broad Tumor PortalSLC6A5
OASIS PortalSLC6A5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSLC6A5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSLC6A5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
BioMutasearch SLC6A5
DgiDB (Drug Gene Interaction Database)SLC6A5
DoCM (Curated mutations)SLC6A5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SLC6A5 (select a term)
intoGenSLC6A5
Cancer3DSLC6A5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604159    614618   
Orphanet2862   
MedgenSLC6A5
Genetic Testing Registry SLC6A5
NextProtQ9Y345 [Medical]
TSGene9152
GENETestsSLC6A5
Target ValidationSLC6A5
Huge Navigator SLC6A5 [HugePedia]
snp3D : Map Gene to Disease9152
BioCentury BCIQSLC6A5
ClinGenSLC6A5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9152
Chemical/Pharm GKB GenePA35911
Clinical trialSLC6A5
Miscellaneous
canSAR (ICR)SLC6A5 (select the gene name)
Probes
Litterature
PubMed32 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSLC6A5
EVEXSLC6A5
GoPubMedSLC6A5
iHOPSLC6A5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed May 31 15:41:26 CEST 2017

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