Atlas of Genetics and Cytogenetics in Oncology and Haematology


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SLC6A6 (solute carrier family 6 member 6)

Identity

Alias (NCBI)TAUT
HGNC (Hugo) SLC6A6
HGNC Alias symbTAUT
HGNC Alias nametaurine transporter
HGNC Previous namesolute carrier family 6 (neurotransmitter transporter, taurine), member 6
 solute carrier family 6 (neurotransmitter transporter), member 6
LocusID (NCBI) 6533
Atlas_Id 50889
Location 3p25.1  [Link to chromosome band 3p25]
Location_base_pair Starts at 14402576 and ends at 14489349 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
SLC6A6 (3p25.1) / GSDMB (17q12)SLC6A6 (3p25.1) / SLC6A6 (3p25.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)SLC6A6   11052
Cards
Entrez_Gene (NCBI)SLC6A6    solute carrier family 6 member 6
AliasesTAUT
GeneCards (Weizmann)SLC6A6
Ensembl hg19 (Hinxton)ENSG00000131389 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000131389 [Gene_View]  ENSG00000131389 [Sequence]  chr3:14402576-14489349 [Contig_View]  SLC6A6 [Vega]
ICGC DataPortalENSG00000131389
TCGA cBioPortalSLC6A6
AceView (NCBI)SLC6A6
Genatlas (Paris)SLC6A6
SOURCE (Princeton)SLC6A6
Genetics Home Reference (NIH)SLC6A6
Genomic and cartography
GoldenPath hg38 (UCSC)SLC6A6  -     chr3:14402576-14489349 +  3p25.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SLC6A6  -     3p25.1   [Description]    (hg19-Feb_2009)
GoldenPathSLC6A6 - 3p25.1 [CytoView hg19]  SLC6A6 - 3p25.1 [CytoView hg38]
ImmunoBaseENSG00000131389
Genome Data Viewer NCBISLC6A6 [Mapview hg19]  
OMIM186854   
Gene and transcription
Genbank (Entrez)AB209172 AF346763 AK303649 AK307284 AK308417
RefSeq transcript (Entrez)NM_001134367 NM_001134368 NM_003043
Consensus coding sequences : CCDS (NCBI)SLC6A6
Gene ExpressionSLC6A6 [ NCBI-GEO ]   SLC6A6 [ EBI - ARRAY_EXPRESS ]   SLC6A6 [ SEEK ]   SLC6A6 [ MEM ]
Gene Expression Viewer (FireBrowse)SLC6A6 [ Firebrowse - Broad ]
GenevisibleExpression of SLC6A6 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6533
GTEX Portal (Tissue expression)SLC6A6
Human Protein AtlasENSG00000131389-SLC6A6 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP31641   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP31641  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP31641
PhosPhoSitePlusP31641
Domaine pattern : Prosite (Expaxy)NA_NEUROTRAN_SYMP_1 (PS00610)    NA_NEUROTRAN_SYMP_2 (PS00754)    NA_NEUROTRAN_SYMP_3 (PS50267)   
Domains : Interpro (EBI)Na/ntran_symport    Na/ntran_symport_taurine    SNS_sf   
Domain families : Pfam (Sanger)SNF (PF00209)   
Domain families : Pfam (NCBI)pfam00209   
Conserved Domain (NCBI)SLC6A6
SuperfamilyP31641
AlphaFold pdb e-kbP31641   
Human Protein Atlas [tissue]ENSG00000131389-SLC6A6 [tissue]
HPRD01734
Protein Interaction databases
DIP (DOE-UCLA)P31641
IntAct (EBI)P31641
BioGRIDSLC6A6
STRING (EMBL)SLC6A6
ZODIACSLC6A6
Ontologies - Pathways
QuickGOP31641
Ontology : AmiGOtaurine transmembrane transporter activity  taurine transmembrane transporter activity  taurine transmembrane transporter activity  taurine:sodium symporter activity  plasma membrane  plasma membrane  plasma membrane  integral component of plasma membrane  neurotransmitter transport  amino acid transport  positive regulation of necrotic cell death  amino acid transmembrane transporter activity  gamma-aminobutyric acid transmembrane transporter activity  taurine transport  taurine transport  taurine transport  taurine transport  taurine transport  integral component of membrane  basolateral plasma membrane  apical plasma membrane  alanine transmembrane transporter activity  dendrite  microvillus membrane  alanine transport  sodium ion transmembrane transport  neuronal cell body  positive regulation of cell differentiation  modulation of chemical synaptic transmission  gamma-aminobutyric acid import  nitrogen compound transport  amino acid import across plasma membrane  import across plasma membrane  plasma membrane protein complex  GABA-ergic synapse  integral component of postsynaptic membrane  transport across blood-brain barrier  
Ontology : EGO-EBItaurine transmembrane transporter activity  taurine transmembrane transporter activity  taurine transmembrane transporter activity  taurine:sodium symporter activity  plasma membrane  plasma membrane  plasma membrane  integral component of plasma membrane  neurotransmitter transport  amino acid transport  positive regulation of necrotic cell death  amino acid transmembrane transporter activity  gamma-aminobutyric acid transmembrane transporter activity  taurine transport  taurine transport  taurine transport  taurine transport  taurine transport  integral component of membrane  basolateral plasma membrane  apical plasma membrane  alanine transmembrane transporter activity  dendrite  microvillus membrane  alanine transport  sodium ion transmembrane transport  neuronal cell body  positive regulation of cell differentiation  modulation of chemical synaptic transmission  gamma-aminobutyric acid import  nitrogen compound transport  amino acid import across plasma membrane  import across plasma membrane  plasma membrane protein complex  GABA-ergic synapse  integral component of postsynaptic membrane  transport across blood-brain barrier  
NDEx NetworkSLC6A6
Atlas of Cancer Signalling NetworkSLC6A6
Wikipedia pathwaysSLC6A6
Orthology - Evolution
OrthoDB6533
GeneTree (enSembl)ENSG00000131389
Phylogenetic Trees/Animal Genes : TreeFamSLC6A6
Homologs : HomoloGeneSLC6A6
Homology/Alignments : Family Browser (UCSC)SLC6A6
Gene fusions - Rearrangements
Fusion Cancer (Beijing)SLC6A6 [3p25.1]  -  GSDMB [17q12]  [FUSC003749]
Fusion : QuiverSLC6A6
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSLC6A6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SLC6A6
dbVarSLC6A6
ClinVarSLC6A6
MonarchSLC6A6
1000_GenomesSLC6A6 
Exome Variant ServerSLC6A6
GNOMAD BrowserENSG00000131389
Varsome BrowserSLC6A6
ACMGSLC6A6 variants
VarityP31641
Genomic Variants (DGV)SLC6A6 [DGVbeta]
DECIPHERSLC6A6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSLC6A6 
Mutations
ICGC Data PortalSLC6A6 
TCGA Data PortalSLC6A6 
Broad Tumor PortalSLC6A6
OASIS PortalSLC6A6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSLC6A6  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DSLC6A6
Mutations and Diseases : HGMDSLC6A6
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaSLC6A6
DgiDB (Drug Gene Interaction Database)SLC6A6
DoCM (Curated mutations)SLC6A6
CIViC (Clinical Interpretations of Variants in Cancer)SLC6A6
Cancer3DSLC6A6
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM186854   
Orphanet
DisGeNETSLC6A6
MedgenSLC6A6
Genetic Testing Registry SLC6A6
NextProtP31641 [Medical]
GENETestsSLC6A6
Target ValidationSLC6A6
Huge Navigator SLC6A6 [HugePedia]
ClinGenSLC6A6
Clinical trials, drugs, therapy
MyCancerGenomeSLC6A6
Protein Interactions : CTDSLC6A6
Pharm GKB GenePA35912
PharosP31641
Clinical trialSLC6A6
Miscellaneous
canSAR (ICR)SLC6A6
HarmonizomeSLC6A6
DataMed IndexSLC6A6
Probes
Litterature
PubMed65 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXSLC6A6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:31:58 CEST 2021

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