Atlas of Genetics and Cytogenetics in Oncology and Haematology


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SLC7A1 (solute carrier family 7 member 1)

Identity

Alias_namesERR
ATRC1
solute carrier family 7 (cationic amino acid transporter
Alias_symbol (synonym)CAT-1
HCAT1
REC1L
Other alias
HGNC (Hugo) SLC7A1
LocusID (NCBI) 6541
Atlas_Id 54032
Location 13q12.3  [Link to chromosome band 13q12]
Location_base_pair Starts at 30083551 and ends at 30169825 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
NCOA2 (8q13.3) / SLC7A1 (13q12.3)SLC7A1 (13q12.3) / RIDA (8q22.2)SLC7A1 13q12.3 / HRSP12 8q22.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SLC7A1   11057
Cards
Entrez_Gene (NCBI)SLC7A1  6541  solute carrier family 7 member 1
AliasesATRC1; CAT-1; ERR; HCAT1; 
REC1L
GeneCards (Weizmann)SLC7A1
Ensembl hg19 (Hinxton)ENSG00000139514 [Gene_View]  chr13:30083551-30169825 [Contig_View]  SLC7A1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000139514 [Gene_View]  chr13:30083551-30169825 [Contig_View]  SLC7A1 [Vega]
ICGC DataPortalENSG00000139514
TCGA cBioPortalSLC7A1
AceView (NCBI)SLC7A1
Genatlas (Paris)SLC7A1
WikiGenes6541
SOURCE (Princeton)SLC7A1
Genetics Home Reference (NIH)SLC7A1
Genomic and cartography
GoldenPath hg19 (UCSC)SLC7A1  -     chr13:30083551-30169825 -  13q12.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)SLC7A1  -     13q12.3   [Description]    (hg38-Dec_2013)
EnsemblSLC7A1 - 13q12.3 [CytoView hg19]  SLC7A1 - 13q12.3 [CytoView hg38]
Mapping of homologs : NCBISLC7A1 [Mapview hg19]  SLC7A1 [Mapview hg38]
OMIM104615   
Gene and transcription
Genbank (Entrez)AA527433 AB105377 AF078107 AI362952 AK022999
RefSeq transcript (Entrez)NM_003045
RefSeq genomic (Entrez)NC_000013 NC_018924 NT_024524 NW_004929388
Consensus coding sequences : CCDS (NCBI)SLC7A1
Cluster EST : UnigeneHs.14846 [ NCBI ]
CGAP (NCI)Hs.14846
Alternative Splicing GalleryENSG00000139514
Gene ExpressionSLC7A1 [ NCBI-GEO ]   SLC7A1 [ EBI - ARRAY_EXPRESS ]   SLC7A1 [ SEEK ]   SLC7A1 [ MEM ]
Gene Expression Viewer (FireBrowse)SLC7A1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6541
GTEX Portal (Tissue expression)SLC7A1
Protein : pattern, domain, 3D structure
UniProt/SwissProtP30825   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP30825  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP30825
Splice isoforms : SwissVarP30825
PhosPhoSitePlusP30825
Domains : Interpro (EBI)AA/rel_permease1    Cat_AA_permease    CAT_C   
Domain families : Pfam (Sanger)AA_permease_2 (PF13520)    AA_permease_C (PF13906)   
Domain families : Pfam (NCBI)pfam13520    pfam13906   
Conserved Domain (NCBI)SLC7A1
DMDM Disease mutations6541
Blocks (Seattle)SLC7A1
SuperfamilyP30825
Human Protein AtlasENSG00000139514
Peptide AtlasP30825
HPRD00091
IPIIPI00027728   IPI00984184   IPI00646503   
Protein Interaction databases
DIP (DOE-UCLA)P30825
IntAct (EBI)P30825
FunCoupENSG00000139514
BioGRIDSLC7A1
STRING (EMBL)SLC7A1
ZODIACSLC7A1
Ontologies - Pathways
QuickGOP30825
Ontology : AmiGOL-ornithine transmembrane transporter activity  protein binding  plasma membrane  integral component of plasma membrane  transport  amino acid transport  amino acid transmembrane transporter activity  arginine transmembrane transporter activity  L-lysine transmembrane transporter activity  antiporter activity  membrane  L-ornithine transmembrane transport  L-lysine transmembrane transport  arginine transmembrane transport  
Ontology : EGO-EBIL-ornithine transmembrane transporter activity  protein binding  plasma membrane  integral component of plasma membrane  transport  amino acid transport  amino acid transmembrane transporter activity  arginine transmembrane transporter activity  L-lysine transmembrane transporter activity  antiporter activity  membrane  L-ornithine transmembrane transport  L-lysine transmembrane transport  arginine transmembrane transport  
Pathways : BIOCARTAActions of Nitric Oxide in the Heart [Genes]   
Pathways : KEGGMicroRNAs in cancer   
NDEx NetworkSLC7A1
Atlas of Cancer Signalling NetworkSLC7A1
Wikipedia pathwaysSLC7A1
Orthology - Evolution
OrthoDB6541
GeneTree (enSembl)ENSG00000139514
Phylogenetic Trees/Animal Genes : TreeFamSLC7A1
HOVERGENP30825
HOGENOMP30825
Homologs : HomoloGeneSLC7A1
Homology/Alignments : Family Browser (UCSC)SLC7A1
Gene fusions - Rearrangements
Fusion : MitelmanSLC7A1/HRSP12 [13q12.3/8q22.2]  
Fusion: TCGASLC7A1 13q12.3 HRSP12 8q22.2 PRAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSLC7A1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SLC7A1
dbVarSLC7A1
ClinVarSLC7A1
1000_GenomesSLC7A1 
Exome Variant ServerSLC7A1
ExAC (Exome Aggregation Consortium)SLC7A1 (select the gene name)
Genetic variants : HAPMAP6541
Genomic Variants (DGV)SLC7A1 [DGVbeta]
DECIPHER (Syndromes)13:30083551-30169825  ENSG00000139514
CONAN: Copy Number AnalysisSLC7A1 
Mutations
ICGC Data PortalSLC7A1 
TCGA Data PortalSLC7A1 
Broad Tumor PortalSLC7A1
OASIS PortalSLC7A1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSLC7A1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSLC7A1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SLC7A1
DgiDB (Drug Gene Interaction Database)SLC7A1
DoCM (Curated mutations)SLC7A1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SLC7A1 (select a term)
intoGenSLC7A1
Cancer3DSLC7A1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM104615   
Orphanet
MedgenSLC7A1
Genetic Testing Registry SLC7A1
NextProtP30825 [Medical]
TSGene6541
GENETestsSLC7A1
Huge Navigator SLC7A1 [HugePedia]
snp3D : Map Gene to Disease6541
BioCentury BCIQSLC7A1
ClinGenSLC7A1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6541
Chemical/Pharm GKB GenePA35917
Clinical trialSLC7A1
Miscellaneous
canSAR (ICR)SLC7A1 (select the gene name)
Probes
Litterature
PubMed43 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSLC7A1
EVEXSLC7A1
GoPubMedSLC7A1
iHOPSLC7A1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 30 15:19:55 CEST 2017

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