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SLC7A13 (solute carrier family 7 member 13)

Identity

Alias_namessolute carrier family 7 (anionic amino acid transporter)
Alias_symbol (synonym)AGT-1
XAT2
Other aliasAGT1
HGNC (Hugo) SLC7A13
LocusID (NCBI) 157724
Atlas_Id 54641
Location 8q21.3  [Link to chromosome band 8q21]
Location_base_pair Starts at 86214059 and ends at 86230375 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
SLC7A13 (8q21.3) / WDTC1 (1p36.11)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  Lung: Translocations in Squamous Cell Carcinoma


External links

Nomenclature
HGNC (Hugo)SLC7A13   23092
Cards
Entrez_Gene (NCBI)SLC7A13  157724  solute carrier family 7 member 13
AliasesAGT-1; AGT1; XAT2
GeneCards (Weizmann)SLC7A13
Ensembl hg19 (Hinxton)ENSG00000164893 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000164893 [Gene_View]  chr8:86214059-86230375 [Contig_View]  SLC7A13 [Vega]
ICGC DataPortalENSG00000164893
TCGA cBioPortalSLC7A13
AceView (NCBI)SLC7A13
Genatlas (Paris)SLC7A13
WikiGenes157724
SOURCE (Princeton)SLC7A13
Genetics Home Reference (NIH)SLC7A13
Genomic and cartography
GoldenPath hg38 (UCSC)SLC7A13  -     chr8:86214059-86230375 -  8q21.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SLC7A13  -     8q21.3   [Description]    (hg19-Feb_2009)
EnsemblSLC7A13 - 8q21.3 [CytoView hg19]  SLC7A13 - 8q21.3 [CytoView hg38]
Mapping of homologs : NCBISLC7A13 [Mapview hg19]  SLC7A13 [Mapview hg38]
OMIM617256   
Gene and transcription
Genbank (Entrez)AJ417661 AK055815 BC029436 BC125165 BC125166
RefSeq transcript (Entrez)NM_138817
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SLC7A13
Cluster EST : UnigeneHs.149095 [ NCBI ]
CGAP (NCI)Hs.149095
Alternative Splicing GalleryENSG00000164893
Gene ExpressionSLC7A13 [ NCBI-GEO ]   SLC7A13 [ EBI - ARRAY_EXPRESS ]   SLC7A13 [ SEEK ]   SLC7A13 [ MEM ]
Gene Expression Viewer (FireBrowse)SLC7A13 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)157724
GTEX Portal (Tissue expression)SLC7A13
Human Protein AtlasENSG00000164893-SLC7A13 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8TCU3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8TCU3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8TCU3
Splice isoforms : SwissVarQ8TCU3
PhosPhoSitePlusQ8TCU3
Domains : Interpro (EBI)AA/rel_permease1   
Domain families : Pfam (Sanger)AA_permease_2 (PF13520)   
Domain families : Pfam (NCBI)pfam13520   
Conserved Domain (NCBI)SLC7A13
DMDM Disease mutations157724
Blocks (Seattle)SLC7A13
SuperfamilyQ8TCU3
Human Protein Atlas [tissue]ENSG00000164893-SLC7A13 [tissue]
Peptide AtlasQ8TCU3
HPRD15397
IPIIPI00291186   IPI00890695   
Protein Interaction databases
DIP (DOE-UCLA)Q8TCU3
IntAct (EBI)Q8TCU3
FunCoupENSG00000164893
BioGRIDSLC7A13
STRING (EMBL)SLC7A13
ZODIACSLC7A13
Ontologies - Pathways
QuickGOQ8TCU3
Ontology : AmiGOintegral component of plasma membrane  L-amino acid transmembrane transporter activity  antiporter activity  L-alpha-amino acid transmembrane transport  
Ontology : EGO-EBIintegral component of plasma membrane  L-amino acid transmembrane transporter activity  antiporter activity  L-alpha-amino acid transmembrane transport  
NDEx NetworkSLC7A13
Atlas of Cancer Signalling NetworkSLC7A13
Wikipedia pathwaysSLC7A13
Orthology - Evolution
OrthoDB157724
GeneTree (enSembl)ENSG00000164893
Phylogenetic Trees/Animal Genes : TreeFamSLC7A13
HOVERGENQ8TCU3
HOGENOMQ8TCU3
Homologs : HomoloGeneSLC7A13
Homology/Alignments : Family Browser (UCSC)SLC7A13
Gene fusions - Rearrangements
Fusion : MitelmanSLC7A13/WDTC1 [8q21.3/1p36.11]  
Tumor Fusion PortalSLC7A13
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSLC7A13 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SLC7A13
dbVarSLC7A13
ClinVarSLC7A13
1000_GenomesSLC7A13 
Exome Variant ServerSLC7A13
ExAC (Exome Aggregation Consortium)ENSG00000164893
GNOMAD BrowserENSG00000164893
Genetic variants : HAPMAP157724
Genomic Variants (DGV)SLC7A13 [DGVbeta]
DECIPHERSLC7A13 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSLC7A13 
Mutations
ICGC Data PortalSLC7A13 
TCGA Data PortalSLC7A13 
Broad Tumor PortalSLC7A13
OASIS PortalSLC7A13 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSLC7A13  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSLC7A13
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch SLC7A13
DgiDB (Drug Gene Interaction Database)SLC7A13
DoCM (Curated mutations)SLC7A13 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SLC7A13 (select a term)
intoGenSLC7A13
Cancer3DSLC7A13(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM617256   
Orphanet
DisGeNETSLC7A13
MedgenSLC7A13
Genetic Testing Registry SLC7A13
NextProtQ8TCU3 [Medical]
TSGene157724
GENETestsSLC7A13
Target ValidationSLC7A13
Huge Navigator SLC7A13 [HugePedia]
snp3D : Map Gene to Disease157724
BioCentury BCIQSLC7A13
ClinGenSLC7A13
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD157724
Chemical/Pharm GKB GenePA134980828
Clinical trialSLC7A13
Miscellaneous
canSAR (ICR)SLC7A13 (select the gene name)
Probes
Litterature
PubMed6 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSLC7A13
EVEXSLC7A13
GoPubMedSLC7A13
iHOPSLC7A13
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 14:35:23 CET 2017

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