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SLC7A4 (solute carrier family 7 member 4)

Identity

Alias_namessolute carrier family 7 (cationic amino acid transporter, y+ system), member 4
solute carrier family 7 (orphan transporter), member 4
solute carrier family 7, member 4
Alias_symbol (synonym)HCAT3
CAT-4
VH
Other aliasCAT4
HGNC (Hugo) SLC7A4
LocusID (NCBI) 6545
Atlas_Id 73486
Location 22q11.21  [Link to chromosome band 22q11]
Location_base_pair Starts at 21028718 and ends at 21032558 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SLC7A4   11062
Cards
Entrez_Gene (NCBI)SLC7A4  6545  solute carrier family 7 member 4
AliasesCAT-4; CAT4; HCAT3; VH
GeneCards (Weizmann)SLC7A4
Ensembl hg19 (Hinxton)ENSG00000099960 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000099960 [Gene_View]  chr22:21028718-21032558 [Contig_View]  SLC7A4 [Vega]
ICGC DataPortalENSG00000099960
TCGA cBioPortalSLC7A4
AceView (NCBI)SLC7A4
Genatlas (Paris)SLC7A4
WikiGenes6545
SOURCE (Princeton)SLC7A4
Genetics Home Reference (NIH)SLC7A4
Genomic and cartography
GoldenPath hg38 (UCSC)SLC7A4  -     chr22:21028718-21032558 -  22q11.21   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SLC7A4  -     22q11.21   [Description]    (hg19-Feb_2009)
EnsemblSLC7A4 - 22q11.21 [CytoView hg19]  SLC7A4 - 22q11.21 [CytoView hg38]
Mapping of homologs : NCBISLC7A4 [Mapview hg19]  SLC7A4 [Mapview hg38]
OMIM603752   
Gene and transcription
Genbank (Entrez)AJ000730 BC008814 BC062565 BC107160 BC107161
RefSeq transcript (Entrez)NM_004173
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SLC7A4
Cluster EST : UnigeneHs.197116 [ NCBI ]
CGAP (NCI)Hs.197116
Alternative Splicing GalleryENSG00000099960
Gene ExpressionSLC7A4 [ NCBI-GEO ]   SLC7A4 [ EBI - ARRAY_EXPRESS ]   SLC7A4 [ SEEK ]   SLC7A4 [ MEM ]
Gene Expression Viewer (FireBrowse)SLC7A4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6545
GTEX Portal (Tissue expression)SLC7A4
Protein : pattern, domain, 3D structure
UniProt/SwissProtO43246   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO43246  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO43246
Splice isoforms : SwissVarO43246
PhosPhoSitePlusO43246
Domains : Interpro (EBI)AA/rel_permease1    CAT_C   
Domain families : Pfam (Sanger)AA_permease_2 (PF13520)    AA_permease_C (PF13906)   
Domain families : Pfam (NCBI)pfam13520    pfam13906   
Conserved Domain (NCBI)SLC7A4
DMDM Disease mutations6545
Blocks (Seattle)SLC7A4
SuperfamilyO43246
Human Protein AtlasENSG00000099960
Peptide AtlasO43246
HPRD04780
IPIIPI00748296   IPI00879886   
Protein Interaction databases
DIP (DOE-UCLA)O43246
IntAct (EBI)O43246
FunCoupENSG00000099960
BioGRIDSLC7A4
STRING (EMBL)SLC7A4
ZODIACSLC7A4
Ontologies - Pathways
QuickGOO43246
Ontology : AmiGOcellular amino acid metabolic process  transport  basic amino acid transmembrane transporter activity  integral component of membrane  basic amino acid transmembrane transport  
Ontology : EGO-EBIcellular amino acid metabolic process  transport  basic amino acid transmembrane transporter activity  integral component of membrane  basic amino acid transmembrane transport  
NDEx NetworkSLC7A4
Atlas of Cancer Signalling NetworkSLC7A4
Wikipedia pathwaysSLC7A4
Orthology - Evolution
OrthoDB6545
GeneTree (enSembl)ENSG00000099960
Phylogenetic Trees/Animal Genes : TreeFamSLC7A4
HOVERGENO43246
HOGENOMO43246
Homologs : HomoloGeneSLC7A4
Homology/Alignments : Family Browser (UCSC)SLC7A4
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSLC7A4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SLC7A4
dbVarSLC7A4
ClinVarSLC7A4
1000_GenomesSLC7A4 
Exome Variant ServerSLC7A4
ExAC (Exome Aggregation Consortium)SLC7A4 (select the gene name)
Genetic variants : HAPMAP6545
Genomic Variants (DGV)SLC7A4 [DGVbeta]
DECIPHERSLC7A4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSLC7A4 
Mutations
ICGC Data PortalSLC7A4 
TCGA Data PortalSLC7A4 
Broad Tumor PortalSLC7A4
OASIS PortalSLC7A4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSLC7A4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSLC7A4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SLC7A4
DgiDB (Drug Gene Interaction Database)SLC7A4
DoCM (Curated mutations)SLC7A4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SLC7A4 (select a term)
intoGenSLC7A4
Cancer3DSLC7A4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603752   
Orphanet
MedgenSLC7A4
Genetic Testing Registry SLC7A4
NextProtO43246 [Medical]
TSGene6545
GENETestsSLC7A4
Target ValidationSLC7A4
Huge Navigator SLC7A4 [HugePedia]
snp3D : Map Gene to Disease6545
BioCentury BCIQSLC7A4
ClinGenSLC7A4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6545
Chemical/Pharm GKB GenePA35922
Clinical trialSLC7A4
Miscellaneous
canSAR (ICR)SLC7A4 (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSLC7A4
EVEXSLC7A4
GoPubMedSLC7A4
iHOPSLC7A4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:38:19 CEST 2017

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