Atlas of Genetics and Cytogenetics in Oncology and Haematology


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SLC7A7 (solute carrier family 7 member 7)

Identity

Alias_namesLPI
solute carrier family 7 (amino acid transporter light chain
Alias_symbol (synonym)y??1
Other aliasLAT3
MOP-2
Y+LAT1
y+LAT-1
HGNC (Hugo) SLC7A7
LocusID (NCBI) 9056
Atlas_Id 53539
Location 14q11.2  [Link to chromosome band 14q11]
Location_base_pair Starts at 23242432 and ends at 23285107 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
LOC100507412 (-) / SLC7A7 (14q11.2)PVT1 (8q24.21) / SLC7A7 (14q11.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  Lung: Translocations in Small Cell Carcinoma


External links

Nomenclature
HGNC (Hugo)SLC7A7   11065
LRG (Locus Reference Genomic)LRG_695
Cards
Entrez_Gene (NCBI)SLC7A7  9056  solute carrier family 7 member 7
AliasesLAT3; LPI; MOP-2; Y+LAT1; 
y+LAT-1
GeneCards (Weizmann)SLC7A7
Ensembl hg19 (Hinxton)ENSG00000155465 [Gene_View]  chr14:23242432-23285107 [Contig_View]  SLC7A7 [Vega]
Ensembl hg38 (Hinxton)ENSG00000155465 [Gene_View]  chr14:23242432-23285107 [Contig_View]  SLC7A7 [Vega]
ICGC DataPortalENSG00000155465
TCGA cBioPortalSLC7A7
AceView (NCBI)SLC7A7
Genatlas (Paris)SLC7A7
WikiGenes9056
SOURCE (Princeton)SLC7A7
Genetics Home Reference (NIH)SLC7A7
Genomic and cartography
GoldenPath hg19 (UCSC)SLC7A7  -     chr14:23242432-23285107 -  14q11.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)SLC7A7  -     14q11.2   [Description]    (hg38-Dec_2013)
EnsemblSLC7A7 - 14q11.2 [CytoView hg19]  SLC7A7 - 14q11.2 [CytoView hg38]
Mapping of homologs : NCBISLC7A7 [Mapview hg19]  SLC7A7 [Mapview hg38]
OMIM222700   603593   
Gene and transcription
Genbank (Entrez)AB011263 AB020532 AB209591 AF092032 AJ130718
RefSeq transcript (Entrez)NM_001126105 NM_001126106 NM_003982
RefSeq genomic (Entrez)NC_000014 NC_018925 NG_012851 NT_026437 NW_004929393
Consensus coding sequences : CCDS (NCBI)SLC7A7
Cluster EST : UnigeneHs.732349 [ NCBI ]
CGAP (NCI)Hs.732349
Alternative Splicing GalleryENSG00000155465
Gene ExpressionSLC7A7 [ NCBI-GEO ]   SLC7A7 [ EBI - ARRAY_EXPRESS ]   SLC7A7 [ SEEK ]   SLC7A7 [ MEM ]
Gene Expression Viewer (FireBrowse)SLC7A7 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9056
GTEX Portal (Tissue expression)SLC7A7
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UM01   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UM01  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UM01
Splice isoforms : SwissVarQ9UM01
PhosPhoSitePlusQ9UM01
Domains : Interpro (EBI)AA/rel_permease1   
Domain families : Pfam (Sanger)AA_permease_2 (PF13520)   
Domain families : Pfam (NCBI)pfam13520   
Conserved Domain (NCBI)SLC7A7
DMDM Disease mutations9056
Blocks (Seattle)SLC7A7
SuperfamilyQ9UM01
Human Protein AtlasENSG00000155465
Peptide AtlasQ9UM01
HPRD04667
IPIIPI00549477   IPI00910358   IPI01026256   IPI01026352   IPI01017898   IPI01026293   IPI01025948   IPI01026044   IPI01025506   IPI01025610   IPI01025429   IPI00965215   
Protein Interaction databases
DIP (DOE-UCLA)Q9UM01
IntAct (EBI)Q9UM01
FunCoupENSG00000155465
BioGRIDSLC7A7
STRING (EMBL)SLC7A7
ZODIACSLC7A7
Ontologies - Pathways
QuickGOQ9UM01
Ontology : AmiGOregulation of arginine metabolic process  plasma membrane  integral component of plasma membrane  protein complex assembly  cellular amino acid metabolic process  transport  amino acid transport  basic amino acid transmembrane transporter activity  L-amino acid transmembrane transporter activity  antiporter activity  L-amino acid transport  basolateral plasma membrane  leukocyte migration  L-alpha-amino acid transmembrane transport  basic amino acid transmembrane transport  
Ontology : EGO-EBIregulation of arginine metabolic process  plasma membrane  integral component of plasma membrane  protein complex assembly  cellular amino acid metabolic process  transport  amino acid transport  basic amino acid transmembrane transporter activity  L-amino acid transmembrane transporter activity  antiporter activity  L-amino acid transport  basolateral plasma membrane  leukocyte migration  L-alpha-amino acid transmembrane transport  basic amino acid transmembrane transport  
Pathways : KEGGProtein digestion and absorption   
NDEx NetworkSLC7A7
Atlas of Cancer Signalling NetworkSLC7A7
Wikipedia pathwaysSLC7A7
Orthology - Evolution
OrthoDB9056
GeneTree (enSembl)ENSG00000155465
Phylogenetic Trees/Animal Genes : TreeFamSLC7A7
HOVERGENQ9UM01
HOGENOMQ9UM01
Homologs : HomoloGeneSLC7A7
Homology/Alignments : Family Browser (UCSC)SLC7A7
Gene fusions - Rearrangements
Fusion : MitelmanPVT1/SLC7A7 [8q24.21/14q11.2]  [t(8;14)(q24;q11)]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSLC7A7 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SLC7A7
dbVarSLC7A7
ClinVarSLC7A7
1000_GenomesSLC7A7 
Exome Variant ServerSLC7A7
ExAC (Exome Aggregation Consortium)SLC7A7 (select the gene name)
Genetic variants : HAPMAP9056
Genomic Variants (DGV)SLC7A7 [DGVbeta]
DECIPHER (Syndromes)14:23242432-23285107  ENSG00000155465
CONAN: Copy Number AnalysisSLC7A7 
Mutations
ICGC Data PortalSLC7A7 
TCGA Data PortalSLC7A7 
Broad Tumor PortalSLC7A7
OASIS PortalSLC7A7 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSLC7A7  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSLC7A7
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)**PUBLIC** CCHMC Molecular Genetics Laboratory Mutation Database
BioMutasearch SLC7A7
DgiDB (Drug Gene Interaction Database)SLC7A7
DoCM (Curated mutations)SLC7A7 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SLC7A7 (select a term)
intoGenSLC7A7
Cancer3DSLC7A7(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM222700    603593   
Orphanet3366   
MedgenSLC7A7
Genetic Testing Registry SLC7A7
NextProtQ9UM01 [Medical]
TSGene9056
GENETestsSLC7A7
Huge Navigator SLC7A7 [HugePedia]
snp3D : Map Gene to Disease9056
BioCentury BCIQSLC7A7
ClinGenSLC7A7
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9056
Chemical/Pharm GKB GenePA35925
Clinical trialSLC7A7
Miscellaneous
canSAR (ICR)SLC7A7 (select the gene name)
Probes
Litterature
PubMed30 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSLC7A7
EVEXSLC7A7
GoPubMedSLC7A7
iHOPSLC7A7
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 30 15:19:56 CEST 2017

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