Atlas of Genetics and Cytogenetics in Oncology and Haematology


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SLC8B1 (solute carrier family 8 member B1)

Identity

Alias_namesSLC24A6
solute carrier family 24 (sodium/potassium/calcium exchanger), member 6
solute carrier family 24 (sodium/lithium/calcium exchanger), member 6
solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
Alias_symbol (synonym)FLJ22233
NCKX6
NCLX
Other alias
HGNC (Hugo) SLC8B1
LocusID (NCBI) 80024
Atlas_Id 73494
Location 12q24.13  [Link to chromosome band 12q24]
Location_base_pair Starts at 113298766 and ends at 113335168 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CLIP1 (12q24.31) / SLC8B1 (12q24.13)NTRK3 (15q25.3) / SLC8B1 (12q24.13)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SLC8B1   26175
Cards
Entrez_Gene (NCBI)SLC8B1  80024  solute carrier family 8 member B1
AliasesNCKX6; NCLX; SLC24A6
GeneCards (Weizmann)SLC8B1
Ensembl hg19 (Hinxton)ENSG00000089060 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000089060 [Gene_View]  chr12:113298766-113335168 [Contig_View]  SLC8B1 [Vega]
ICGC DataPortalENSG00000089060
TCGA cBioPortalSLC8B1
AceView (NCBI)SLC8B1
Genatlas (Paris)SLC8B1
WikiGenes80024
SOURCE (Princeton)SLC8B1
Genetics Home Reference (NIH)SLC8B1
Genomic and cartography
GoldenPath hg38 (UCSC)SLC8B1  -     chr12:113298766-113335168 -  12q24.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SLC8B1  -     12q24.13   [Description]    (hg19-Feb_2009)
EnsemblSLC8B1 - 12q24.13 [CytoView hg19]  SLC8B1 - 12q24.13 [CytoView hg38]
Mapping of homologs : NCBISLC8B1 [Mapview hg19]  SLC8B1 [Mapview hg38]
OMIM609841   
Gene and transcription
Genbank (Entrez)AI744705 AK025886 AK056179 AK094074 AK095092
RefSeq transcript (Entrez)NM_001330466 NM_024959
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SLC8B1
Cluster EST : UnigeneHs.286194 [ NCBI ]
CGAP (NCI)Hs.286194
Alternative Splicing GalleryENSG00000089060
Gene ExpressionSLC8B1 [ NCBI-GEO ]   SLC8B1 [ EBI - ARRAY_EXPRESS ]   SLC8B1 [ SEEK ]   SLC8B1 [ MEM ]
Gene Expression Viewer (FireBrowse)SLC8B1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)80024
GTEX Portal (Tissue expression)SLC8B1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6J4K2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6J4K2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6J4K2
Splice isoforms : SwissVarQ6J4K2
PhosPhoSitePlusQ6J4K2
Domains : Interpro (EBI)NaCa_Exmemb   
Domain families : Pfam (Sanger)Na_Ca_ex (PF01699)   
Domain families : Pfam (NCBI)pfam01699   
Conserved Domain (NCBI)SLC8B1
DMDM Disease mutations80024
Blocks (Seattle)SLC8B1
SuperfamilyQ6J4K2
Human Protein AtlasENSG00000089060
Peptide AtlasQ6J4K2
HPRD15354
IPIIPI00017232   IPI00452007   IPI01022967   IPI01020751   IPI01022026   IPI01022804   IPI01022521   IPI01021523   IPI01022297   IPI00981304   
Protein Interaction databases
DIP (DOE-UCLA)Q6J4K2
IntAct (EBI)Q6J4K2
FunCoupENSG00000089060
BioGRIDSLC8B1
STRING (EMBL)SLC8B1
ZODIACSLC8B1
Ontologies - Pathways
QuickGOQ6J4K2
Ontology : AmiGOcalcium:sodium antiporter activity  calcium:sodium antiporter activity  plasma membrane  ion transport  mitochondrial calcium ion transmembrane transport  mitochondrial calcium ion transmembrane transport  calcium:cation antiporter activity  mitochondrial crista  integral component of mitochondrial membrane  sodium ion transmembrane transport  sarcolemma  glucose homeostasis  protein homodimerization activity  regulation of insulin secretion  response to stimulus  regulation of cytosolic calcium ion concentration  mitochondrial calcium ion homeostasis  calcium ion transmembrane transport  regulation of cardiac muscle cell membrane potential  calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential  
Ontology : EGO-EBIcalcium:sodium antiporter activity  calcium:sodium antiporter activity  plasma membrane  ion transport  mitochondrial calcium ion transmembrane transport  mitochondrial calcium ion transmembrane transport  calcium:cation antiporter activity  mitochondrial crista  integral component of mitochondrial membrane  sodium ion transmembrane transport  sarcolemma  glucose homeostasis  protein homodimerization activity  regulation of insulin secretion  response to stimulus  regulation of cytosolic calcium ion concentration  mitochondrial calcium ion homeostasis  calcium ion transmembrane transport  regulation of cardiac muscle cell membrane potential  calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential  
NDEx NetworkSLC8B1
Atlas of Cancer Signalling NetworkSLC8B1
Wikipedia pathwaysSLC8B1
Orthology - Evolution
OrthoDB80024
GeneTree (enSembl)ENSG00000089060
Phylogenetic Trees/Animal Genes : TreeFamSLC8B1
HOVERGENQ6J4K2
HOGENOMQ6J4K2
Homologs : HomoloGeneSLC8B1
Homology/Alignments : Family Browser (UCSC)SLC8B1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSLC8B1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SLC8B1
dbVarSLC8B1
ClinVarSLC8B1
1000_GenomesSLC8B1 
Exome Variant ServerSLC8B1
ExAC (Exome Aggregation Consortium)SLC8B1 (select the gene name)
Genetic variants : HAPMAP80024
Genomic Variants (DGV)SLC8B1 [DGVbeta]
DECIPHERSLC8B1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSLC8B1 
Mutations
ICGC Data PortalSLC8B1 
TCGA Data PortalSLC8B1 
Broad Tumor PortalSLC8B1
OASIS PortalSLC8B1 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDSLC8B1
BioMutasearch SLC8B1
DgiDB (Drug Gene Interaction Database)SLC8B1
DoCM (Curated mutations)SLC8B1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SLC8B1 (select a term)
intoGenSLC8B1
Cancer3DSLC8B1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609841   
Orphanet
MedgenSLC8B1
Genetic Testing Registry SLC8B1
NextProtQ6J4K2 [Medical]
TSGene80024
GENETestsSLC8B1
Target ValidationSLC8B1
Huge Navigator SLC8B1 [HugePedia]
snp3D : Map Gene to Disease80024
BioCentury BCIQSLC8B1
ClinGenSLC8B1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD80024
Chemical/Pharm GKB GenePA134954965
Clinical trialSLC8B1
Miscellaneous
canSAR (ICR)SLC8B1 (select the gene name)
Probes
Litterature
PubMed11 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSLC8B1
EVEXSLC8B1
GoPubMedSLC8B1
iHOPSLC8B1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 31 15:41:29 CEST 2017

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