Atlas of Genetics and Cytogenetics in Oncology and Haematology


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SLC9A2 (solute carrier family 9 member A2)

Identity

Alias_namesNHE2
solute carrier family 9 (sodium/hydrogen exchanger), isoform 2
solute carrier family 9 (sodium/hydrogen exchanger), member 2
solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
Other alias
HGNC (Hugo) SLC9A2
LocusID (NCBI) 6549
Atlas_Id 53991
Location 2q12.1  [Link to chromosome band 2q12]
Location_base_pair Starts at 102619534 and ends at 102711350 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SLC9A2   11072
Cards
Entrez_Gene (NCBI)SLC9A2  6549  solute carrier family 9 member A2
AliasesNHE2
GeneCards (Weizmann)SLC9A2
Ensembl hg19 (Hinxton)ENSG00000115616 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000115616 [Gene_View]  chr2:102619534-102711350 [Contig_View]  SLC9A2 [Vega]
ICGC DataPortalENSG00000115616
TCGA cBioPortalSLC9A2
AceView (NCBI)SLC9A2
Genatlas (Paris)SLC9A2
WikiGenes6549
SOURCE (Princeton)SLC9A2
Genetics Home Reference (NIH)SLC9A2
Genomic and cartography
GoldenPath hg38 (UCSC)SLC9A2  -     chr2:102619534-102711350 +  2q12.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SLC9A2  -     2q12.1   [Description]    (hg19-Feb_2009)
EnsemblSLC9A2 - 2q12.1 [CytoView hg19]  SLC9A2 - 2q12.1 [CytoView hg38]
Mapping of homologs : NCBISLC9A2 [Mapview hg19]  SLC9A2 [Mapview hg38]
OMIM600530   
Gene and transcription
Genbank (Entrez)AA843986 AF073299 AK129936 BC035787 BC136377
RefSeq transcript (Entrez)NM_003048
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SLC9A2
Cluster EST : UnigeneHs.250083 [ NCBI ]
CGAP (NCI)Hs.250083
Alternative Splicing GalleryENSG00000115616
Gene ExpressionSLC9A2 [ NCBI-GEO ]   SLC9A2 [ EBI - ARRAY_EXPRESS ]   SLC9A2 [ SEEK ]   SLC9A2 [ MEM ]
Gene Expression Viewer (FireBrowse)SLC9A2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6549
GTEX Portal (Tissue expression)SLC9A2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UBY0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UBY0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UBY0
Splice isoforms : SwissVarQ9UBY0
PhosPhoSitePlusQ9UBY0
Domains : Interpro (EBI)Cation/H_exchanger    Cation/H_exchanger_CPA1    Na/H_exchanger_2    NaH_exchanger    NHE_CaM-bd   
Domain families : Pfam (Sanger)Na_H_Exchanger (PF00999)    NEXCaM_BD (PF16644)   
Domain families : Pfam (NCBI)pfam00999    pfam16644   
Conserved Domain (NCBI)SLC9A2
DMDM Disease mutations6549
Blocks (Seattle)SLC9A2
SuperfamilyQ9UBY0
Human Protein AtlasENSG00000115616
Peptide AtlasQ9UBY0
HPRD02756
IPIIPI00002841   
Protein Interaction databases
DIP (DOE-UCLA)Q9UBY0
IntAct (EBI)Q9UBY0
FunCoupENSG00000115616
BioGRIDSLC9A2
STRING (EMBL)SLC9A2
ZODIACSLC9A2
Ontologies - Pathways
QuickGOQ9UBY0
Ontology : AmiGOplasma membrane  plasma membrane  ion transport  protein localization  sodium:proton antiporter activity  sodium:proton antiporter activity  potassium:proton antiporter activity  integral component of membrane  regulation of intracellular pH  potassium ion transmembrane transport  sodium ion import across plasma membrane  hydrogen ion transmembrane transport  
Ontology : EGO-EBIplasma membrane  plasma membrane  ion transport  protein localization  sodium:proton antiporter activity  sodium:proton antiporter activity  potassium:proton antiporter activity  integral component of membrane  regulation of intracellular pH  potassium ion transmembrane transport  sodium ion import across plasma membrane  hydrogen ion transmembrane transport  
NDEx NetworkSLC9A2
Atlas of Cancer Signalling NetworkSLC9A2
Wikipedia pathwaysSLC9A2
Orthology - Evolution
OrthoDB6549
GeneTree (enSembl)ENSG00000115616
Phylogenetic Trees/Animal Genes : TreeFamSLC9A2
HOVERGENQ9UBY0
HOGENOMQ9UBY0
Homologs : HomoloGeneSLC9A2
Homology/Alignments : Family Browser (UCSC)SLC9A2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSLC9A2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SLC9A2
dbVarSLC9A2
ClinVarSLC9A2
1000_GenomesSLC9A2 
Exome Variant ServerSLC9A2
ExAC (Exome Aggregation Consortium)SLC9A2 (select the gene name)
Genetic variants : HAPMAP6549
Genomic Variants (DGV)SLC9A2 [DGVbeta]
DECIPHERSLC9A2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSLC9A2 
Mutations
ICGC Data PortalSLC9A2 
TCGA Data PortalSLC9A2 
Broad Tumor PortalSLC9A2
OASIS PortalSLC9A2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSLC9A2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSLC9A2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SLC9A2
DgiDB (Drug Gene Interaction Database)SLC9A2
DoCM (Curated mutations)SLC9A2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SLC9A2 (select a term)
intoGenSLC9A2
Cancer3DSLC9A2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600530   
Orphanet
MedgenSLC9A2
Genetic Testing Registry SLC9A2
NextProtQ9UBY0 [Medical]
TSGene6549
GENETestsSLC9A2
Target ValidationSLC9A2
Huge Navigator SLC9A2 [HugePedia]
snp3D : Map Gene to Disease6549
BioCentury BCIQSLC9A2
ClinGenSLC9A2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6549
Chemical/Pharm GKB GenePA35929
Clinical trialSLC9A2
Miscellaneous
canSAR (ICR)SLC9A2 (select the gene name)
Probes
Litterature
PubMed31 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSLC9A2
EVEXSLC9A2
GoPubMedSLC9A2
iHOPSLC9A2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 17:14:59 CEST 2017

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