SLC9A4 (solute carrier family 9 member A4)

2014-11-01  

Identity

HGNC
LOCATION
2q12.1
LOCUSID
ALIAS
NHE4

Other Information

Locus ID:

NCBI: 389015
MIM: 600531
HGNC: 11077
Ensembl: ENSG00000180251

Variants:

dbSNP: 389015
ClinVar: 389015
TCGA: ENSG00000180251
COSMIC: SLC9A4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000180251ENST00000295269Q6AI14

Expression (GTEx)

0
5
10
15
20
25

Pathways

PathwaySourceExternal ID
Gastric acid secretionKEGGko04971
Gastric acid secretionKEGGhsa04971
Transmembrane transport of small moleculesREACTOMER-HSA-382551
SLC-mediated transmembrane transportREACTOMER-HSA-425407
Transport of inorganic cations/anions and amino acids/oligopeptidesREACTOMER-HSA-425393
Sodium/Proton exchangersREACTOMER-HSA-425986

Protein levels (Protein atlas)

Not detected
Low
Medium
High

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA27745ELF2GenePathwayassociated

References

Pubmed IDYearTitleCitations
179433102008NHE1, NHE2, and NHE4 contribute to regulation of cell pH in T84 colon cancer cells.12
220492132012Functional role of NHE4 as a pH regulator in rat and human colonic crypts.0

Citation

Dessen P

SLC9A4 (solute carrier family 9 member A4)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/73495/slc9a4