Atlas of Genetics and Cytogenetics in Oncology and Haematology


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SLC9A5 (solute carrier family 9 member A5)

Identity

Alias_namessolute carrier family 9 (sodium/hydrogen exchanger), isoform 5
solute carrier family 9 (sodium/hydrogen exchanger), member 5
solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
Alias_symbol (synonym)NHE5
Other alias
HGNC (Hugo) SLC9A5
LocusID (NCBI) 6553
Atlas_Id 73496
Location 16q22.1  [Link to chromosome band 16q22]
Location_base_pair Starts at 67248872 and ends at 67272191 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SLC9A5   11078
Cards
Entrez_Gene (NCBI)SLC9A5  6553  solute carrier family 9 member A5
AliasesNHE5
GeneCards (Weizmann)SLC9A5
Ensembl hg19 (Hinxton)ENSG00000135740 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000135740 [Gene_View]  chr16:67248872-67272191 [Contig_View]  SLC9A5 [Vega]
ICGC DataPortalENSG00000135740
TCGA cBioPortalSLC9A5
AceView (NCBI)SLC9A5
Genatlas (Paris)SLC9A5
WikiGenes6553
SOURCE (Princeton)SLC9A5
Genetics Home Reference (NIH)SLC9A5
Genomic and cartography
GoldenPath hg38 (UCSC)SLC9A5  -     chr16:67248872-67272191 +  16q22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SLC9A5  -     16q22.1   [Description]    (hg19-Feb_2009)
EnsemblSLC9A5 - 16q22.1 [CytoView hg19]  SLC9A5 - 16q22.1 [CytoView hg38]
Mapping of homologs : NCBISLC9A5 [Mapview hg19]  SLC9A5 [Mapview hg38]
OMIM600477   
Gene and transcription
Genbank (Entrez)AB209203 AF111173 AK021876 AK091748 AL137689
RefSeq transcript (Entrez)NM_001323971 NM_001323972 NM_001323973 NM_001323974 NM_001323975 NM_004594
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SLC9A5
Cluster EST : UnigeneHs.439650 [ NCBI ]
CGAP (NCI)Hs.439650
Alternative Splicing GalleryENSG00000135740
Gene ExpressionSLC9A5 [ NCBI-GEO ]   SLC9A5 [ EBI - ARRAY_EXPRESS ]   SLC9A5 [ SEEK ]   SLC9A5 [ MEM ]
Gene Expression Viewer (FireBrowse)SLC9A5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6553
GTEX Portal (Tissue expression)SLC9A5
Human Protein AtlasENSG00000135740-SLC9A5 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ14940   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ14940  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ14940
Splice isoforms : SwissVarQ14940
PhosPhoSitePlusQ14940
Domains : Interpro (EBI)Cation/H_exchanger    Cation/H_exchanger_CPA1    Na/H_exchanger_3/5    NaH_exchanger   
Domain families : Pfam (Sanger)Na_H_Exchanger (PF00999)   
Domain families : Pfam (NCBI)pfam00999   
Conserved Domain (NCBI)SLC9A5
DMDM Disease mutations6553
Blocks (Seattle)SLC9A5
SuperfamilyQ14940
Human Protein Atlas [tissue]ENSG00000135740-SLC9A5 [tissue]
Peptide AtlasQ14940
HPRD02723
IPIIPI00001557   IPI00645686   IPI00556047   
Protein Interaction databases
DIP (DOE-UCLA)Q14940
IntAct (EBI)Q14940
FunCoupENSG00000135740
BioGRIDSLC9A5
STRING (EMBL)SLC9A5
ZODIACSLC9A5
Ontologies - Pathways
QuickGOQ14940
Ontology : AmiGOplasma membrane  plasma membrane  transport  ion transport  sodium:proton antiporter activity  sodium:proton antiporter activity  potassium:proton antiporter activity  integral component of membrane  regulation of intracellular pH  potassium ion transmembrane transport  sodium ion import across plasma membrane  hydrogen ion transmembrane transport  
Ontology : EGO-EBIplasma membrane  plasma membrane  transport  ion transport  sodium:proton antiporter activity  sodium:proton antiporter activity  potassium:proton antiporter activity  integral component of membrane  regulation of intracellular pH  potassium ion transmembrane transport  sodium ion import across plasma membrane  hydrogen ion transmembrane transport  
NDEx NetworkSLC9A5
Atlas of Cancer Signalling NetworkSLC9A5
Wikipedia pathwaysSLC9A5
Orthology - Evolution
OrthoDB6553
GeneTree (enSembl)ENSG00000135740
Phylogenetic Trees/Animal Genes : TreeFamSLC9A5
HOVERGENQ14940
HOGENOMQ14940
Homologs : HomoloGeneSLC9A5
Homology/Alignments : Family Browser (UCSC)SLC9A5
Gene fusions - Rearrangements
Fusion: Tumor Portal SLC9A5
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSLC9A5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SLC9A5
dbVarSLC9A5
ClinVarSLC9A5
1000_GenomesSLC9A5 
Exome Variant ServerSLC9A5
ExAC (Exome Aggregation Consortium)ENSG00000135740
GNOMAD BrowserENSG00000135740
Genetic variants : HAPMAP6553
Genomic Variants (DGV)SLC9A5 [DGVbeta]
DECIPHERSLC9A5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSLC9A5 
Mutations
ICGC Data PortalSLC9A5 
TCGA Data PortalSLC9A5 
Broad Tumor PortalSLC9A5
OASIS PortalSLC9A5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSLC9A5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSLC9A5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SLC9A5
DgiDB (Drug Gene Interaction Database)SLC9A5
DoCM (Curated mutations)SLC9A5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SLC9A5 (select a term)
intoGenSLC9A5
Cancer3DSLC9A5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600477   
Orphanet
MedgenSLC9A5
Genetic Testing Registry SLC9A5
NextProtQ14940 [Medical]
TSGene6553
GENETestsSLC9A5
Target ValidationSLC9A5
Huge Navigator SLC9A5 [HugePedia]
snp3D : Map Gene to Disease6553
BioCentury BCIQSLC9A5
ClinGenSLC9A5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6553
Chemical/Pharm GKB GenePA35934
Clinical trialSLC9A5
Miscellaneous
canSAR (ICR)SLC9A5 (select the gene name)
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSLC9A5
EVEXSLC9A5
GoPubMedSLC9A5
iHOPSLC9A5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Nov 9 12:27:51 CET 2017

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