Atlas of Genetics and Cytogenetics in Oncology and Haematology


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SLC9A6 (solute carrier family 9 member A6)

Identity

Alias_namessolute carrier family 9 (sodium/hydrogen exchanger), isoform 6
solute carrier family 9 (sodium/hydrogen exchanger), member 6
solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6
Alias_symbol (synonym)NHE6
KIAA0267
Other aliasMRSA
HGNC (Hugo) SLC9A6
LocusID (NCBI) 10479
Atlas_Id 73497
Location Xq26.3  [Link to chromosome band Xq26]
Location_base_pair Starts at 135985427 and ends at 136047269 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SLC9A6   11079
Cards
Entrez_Gene (NCBI)SLC9A6  10479  solute carrier family 9 member A6
AliasesMRSA; NHE6
GeneCards (Weizmann)SLC9A6
Ensembl hg19 (Hinxton)ENSG00000198689 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000198689 [Gene_View]  chrX:135985427-136047269 [Contig_View]  SLC9A6 [Vega]
ICGC DataPortalENSG00000198689
TCGA cBioPortalSLC9A6
AceView (NCBI)SLC9A6
Genatlas (Paris)SLC9A6
WikiGenes10479
SOURCE (Princeton)SLC9A6
Genetics Home Reference (NIH)SLC9A6
Genomic and cartography
GoldenPath hg38 (UCSC)SLC9A6  -     chrX:135985427-136047269 +  Xq26.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SLC9A6  -     Xq26.3   [Description]    (hg19-Feb_2009)
EnsemblSLC9A6 - Xq26.3 [CytoView hg19]  SLC9A6 - Xq26.3 [CytoView hg38]
Mapping of homologs : NCBISLC9A6 [Mapview hg19]  SLC9A6 [Mapview hg38]
OMIM300231   300243   
Gene and transcription
Genbank (Entrez)AB074255 AF030409 AK289775 AK296444 AK297218
RefSeq transcript (Entrez)NM_001042537 NM_001177651 NM_001330652 NM_006359
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SLC9A6
Cluster EST : UnigeneHs.62185 [ NCBI ]
CGAP (NCI)Hs.62185
Alternative Splicing GalleryENSG00000198689
Gene ExpressionSLC9A6 [ NCBI-GEO ]   SLC9A6 [ EBI - ARRAY_EXPRESS ]   SLC9A6 [ SEEK ]   SLC9A6 [ MEM ]
Gene Expression Viewer (FireBrowse)SLC9A6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10479
GTEX Portal (Tissue expression)SLC9A6
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ92581   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ92581  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ92581
Splice isoforms : SwissVarQ92581
PhosPhoSitePlusQ92581
Domains : Interpro (EBI)Cation/H_exchanger    Cation/H_exchanger_CPA1    Na/H_exchanger_6    NaH_exchanger   
Domain families : Pfam (Sanger)Na_H_Exchanger (PF00999)   
Domain families : Pfam (NCBI)pfam00999   
Conserved Domain (NCBI)SLC9A6
DMDM Disease mutations10479
Blocks (Seattle)SLC9A6
SuperfamilyQ92581
Human Protein AtlasENSG00000198689
Peptide AtlasQ92581
HPRD02208
IPIIPI00022061   IPI00418972   IPI00647658   
Protein Interaction databases
DIP (DOE-UCLA)Q92581
IntAct (EBI)Q92581
FunCoupENSG00000198689
BioGRIDSLC9A6
STRING (EMBL)SLC9A6
ZODIACSLC9A6
Ontologies - Pathways
QuickGOQ92581
Ontology : AmiGOmitochondrion  early endosome  late endosome  endoplasmic reticulum membrane  plasma membrane  transport  ion transport  sodium:proton antiporter activity  sodium:proton antiporter activity  potassium:proton antiporter activity  integral component of membrane  dendrite  brain-derived neurotrophic factor receptor signaling pathway  early endosome membrane  early endosome membrane  intracellular membrane-bounded organelle  axon terminus  axonal spine  axon extension  neuron projection morphogenesis  synapse organization  regulation of neurotrophin TRK receptor signaling pathway  regulation of intracellular pH  recycling endosome membrane  dendritic spine development  potassium ion transmembrane transport  dendrite extension  sodium ion import across plasma membrane  hydrogen ion transmembrane transport  
Ontology : EGO-EBImitochondrion  early endosome  late endosome  endoplasmic reticulum membrane  plasma membrane  transport  ion transport  sodium:proton antiporter activity  sodium:proton antiporter activity  potassium:proton antiporter activity  integral component of membrane  dendrite  brain-derived neurotrophic factor receptor signaling pathway  early endosome membrane  early endosome membrane  intracellular membrane-bounded organelle  axon terminus  axonal spine  axon extension  neuron projection morphogenesis  synapse organization  regulation of neurotrophin TRK receptor signaling pathway  regulation of intracellular pH  recycling endosome membrane  dendritic spine development  potassium ion transmembrane transport  dendrite extension  sodium ion import across plasma membrane  hydrogen ion transmembrane transport  
Pathways : KEGGCardiac muscle contraction   
NDEx NetworkSLC9A6
Atlas of Cancer Signalling NetworkSLC9A6
Wikipedia pathwaysSLC9A6
Orthology - Evolution
OrthoDB10479
GeneTree (enSembl)ENSG00000198689
Phylogenetic Trees/Animal Genes : TreeFamSLC9A6
HOVERGENQ92581
HOGENOMQ92581
Homologs : HomoloGeneSLC9A6
Homology/Alignments : Family Browser (UCSC)SLC9A6
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSLC9A6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SLC9A6
dbVarSLC9A6
ClinVarSLC9A6
1000_GenomesSLC9A6 
Exome Variant ServerSLC9A6
ExAC (Exome Aggregation Consortium)SLC9A6 (select the gene name)
Genetic variants : HAPMAP10479
Genomic Variants (DGV)SLC9A6 [DGVbeta]
DECIPHERSLC9A6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSLC9A6 
Mutations
ICGC Data PortalSLC9A6 
TCGA Data PortalSLC9A6 
Broad Tumor PortalSLC9A6
OASIS PortalSLC9A6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSLC9A6  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSLC9A6
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SLC9A6
DgiDB (Drug Gene Interaction Database)SLC9A6
DoCM (Curated mutations)SLC9A6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SLC9A6 (select a term)
intoGenSLC9A6
Cancer3DSLC9A6(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300231    300243   
Orphanet11668   
MedgenSLC9A6
Genetic Testing Registry SLC9A6
NextProtQ92581 [Medical]
TSGene10479
GENETestsSLC9A6
Target ValidationSLC9A6
Huge Navigator SLC9A6 [HugePedia]
snp3D : Map Gene to Disease10479
BioCentury BCIQSLC9A6
ClinGenSLC9A6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10479
Chemical/Pharm GKB GenePA35935
Clinical trialSLC9A6
Miscellaneous
canSAR (ICR)SLC9A6 (select the gene name)
Probes
Litterature
PubMed32 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSLC9A6
EVEXSLC9A6
GoPubMedSLC9A6
iHOPSLC9A6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 31 15:41:30 CEST 2017

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