Atlas of Genetics and Cytogenetics in Oncology and Haematology


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SLC9A7 (solute carrier family 9 member A7)

Identity

Alias_namessolute carrier family 9 (sodium/hydrogen exchanger), isoform 7
solute carrier family 9 (sodium/hydrogen exchanger), member 7
solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
Alias_symbol (synonym)NHE7
Other aliasNHE-7
SLC9A6
HGNC (Hugo) SLC9A7
LocusID (NCBI) 84679
Atlas_Id 52687
Location Xp11.3  [Link to chromosome band Xp11]
Location_base_pair Starts at 46599251 and ends at 46759172 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
SLC9A7 (Xp11.23) / ALDH7A1 (5q23.2)SLC9A7 (Xp11.23) / OGT (Xq13.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SLC9A7   17123
Cards
Entrez_Gene (NCBI)SLC9A7  84679  solute carrier family 9 member A7
AliasesNHE-7; NHE7; SLC9A6
GeneCards (Weizmann)SLC9A7
Ensembl hg19 (Hinxton)ENSG00000065923 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000065923 [Gene_View]  chrX:46599251-46759172 [Contig_View]  SLC9A7 [Vega]
ICGC DataPortalENSG00000065923
TCGA cBioPortalSLC9A7
AceView (NCBI)SLC9A7
Genatlas (Paris)SLC9A7
WikiGenes84679
SOURCE (Princeton)SLC9A7
Genetics Home Reference (NIH)SLC9A7
Genomic and cartography
GoldenPath hg38 (UCSC)SLC9A7  -     chrX:46599251-46759172 -  Xp11.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SLC9A7  -     Xp11.3   [Description]    (hg19-Feb_2009)
EnsemblSLC9A7 - Xp11.3 [CytoView hg19]  SLC9A7 - Xp11.3 [CytoView hg38]
Mapping of homologs : NCBISLC9A7 [Mapview hg19]  SLC9A7 [Mapview hg38]
OMIM300368   
Gene and transcription
Genbank (Entrez)AF298591 AI081096 AK056599 AK096921 BC030272
RefSeq transcript (Entrez)NM_001257291 NM_032591
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SLC9A7
Cluster EST : UnigeneHs.91389 [ NCBI ]
CGAP (NCI)Hs.91389
Alternative Splicing GalleryENSG00000065923
Gene ExpressionSLC9A7 [ NCBI-GEO ]   SLC9A7 [ EBI - ARRAY_EXPRESS ]   SLC9A7 [ SEEK ]   SLC9A7 [ MEM ]
Gene Expression Viewer (FireBrowse)SLC9A7 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84679
GTEX Portal (Tissue expression)SLC9A7
Human Protein AtlasENSG00000065923-SLC9A7 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96T83   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96T83  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96T83
Splice isoforms : SwissVarQ96T83
PhosPhoSitePlusQ96T83
Domains : Interpro (EBI)Cation/H_exchanger    Cation/H_exchanger_CPA1    Na/H_exchanger_6    NaH_exchanger   
Domain families : Pfam (Sanger)Na_H_Exchanger (PF00999)   
Domain families : Pfam (NCBI)pfam00999   
Conserved Domain (NCBI)SLC9A7
DMDM Disease mutations84679
Blocks (Seattle)SLC9A7
SuperfamilyQ96T83
Human Protein Atlas [tissue]ENSG00000065923-SLC9A7 [tissue]
Peptide AtlasQ96T83
HPRD02297
IPIIPI00045928   
Protein Interaction databases
DIP (DOE-UCLA)Q96T83
IntAct (EBI)Q96T83
FunCoupENSG00000065923
BioGRIDSLC9A7
STRING (EMBL)SLC9A7
ZODIACSLC9A7
Ontologies - Pathways
QuickGOQ96T83
Ontology : AmiGOGolgi membrane  protein binding  trans-Golgi network  plasma membrane  ion transport  regulation of pH  sodium:proton antiporter activity  sodium:proton antiporter activity  potassium:proton antiporter activity  integral component of membrane  protein homodimerization activity  intracellular membrane-bounded organelle  regulation of intracellular pH  recycling endosome membrane  potassium ion transmembrane transport  sodium ion import across plasma membrane  hydrogen ion transmembrane transport  
Ontology : EGO-EBIGolgi membrane  protein binding  trans-Golgi network  plasma membrane  ion transport  regulation of pH  sodium:proton antiporter activity  sodium:proton antiporter activity  potassium:proton antiporter activity  integral component of membrane  protein homodimerization activity  intracellular membrane-bounded organelle  regulation of intracellular pH  recycling endosome membrane  potassium ion transmembrane transport  sodium ion import across plasma membrane  hydrogen ion transmembrane transport  
NDEx NetworkSLC9A7
Atlas of Cancer Signalling NetworkSLC9A7
Wikipedia pathwaysSLC9A7
Orthology - Evolution
OrthoDB84679
GeneTree (enSembl)ENSG00000065923
Phylogenetic Trees/Animal Genes : TreeFamSLC9A7
HOVERGENQ96T83
HOGENOMQ96T83
Homologs : HomoloGeneSLC9A7
Homology/Alignments : Family Browser (UCSC)SLC9A7
Gene fusions - Rearrangements
Fusion: Tumor Portal SLC9A7
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSLC9A7 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SLC9A7
dbVarSLC9A7
ClinVarSLC9A7
1000_GenomesSLC9A7 
Exome Variant ServerSLC9A7
ExAC (Exome Aggregation Consortium)ENSG00000065923
GNOMAD BrowserENSG00000065923
Genetic variants : HAPMAP84679
Genomic Variants (DGV)SLC9A7 [DGVbeta]
DECIPHERSLC9A7 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSLC9A7 
Mutations
ICGC Data PortalSLC9A7 
TCGA Data PortalSLC9A7 
Broad Tumor PortalSLC9A7
OASIS PortalSLC9A7 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSLC9A7  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSLC9A7
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)X-chromosome gene database
BioMutasearch SLC9A7
DgiDB (Drug Gene Interaction Database)SLC9A7
DoCM (Curated mutations)SLC9A7 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SLC9A7 (select a term)
intoGenSLC9A7
Cancer3DSLC9A7(select the gene naíe)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300368   
Orphanet
MedgenSLC9A7
Genetic Testing Registry SLC9A7
NextProtQ96T83 [Medical]
TSGene84679
GENETestsSLC9A7
Target ValidationSLC9A7
Huge Navigator SLC9A7 [HugePedia]
snp3D : Map Gene to Disease84679
BioCentury BCIQSLC9A7
ClinGenSLC9A7
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD84679
Chemical/Pharm GKB GenePA38200
Clinical trialSLC9A7
Miscellaneous
canSAR (ICR)SLC9A7 (select the gene name)
Probes
Litterature
PubMed12 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSLC9A7
EVEXSLC9A7
GoPubMedSLC9A7
iHOPSLC9A7
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Nov 9 13:11:37 CET 2017

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