SLC9A9 (solute carrier family 9 member A9)

2016-04-01  

Identity

HGNC
SLC9A9
LOCATION
3q24
LOCUSID
285195
ALIAS
AUTS16,NHE9
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 285195
MIM: 608396
HGNC: 20653
Ensembl: ENSG00000181804

Variants:

dbSNP: 285195
ClinVar: 285195
TCGA: ENSG00000181804
COSMIC: SLC9A9

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000181804ENST00000316549Q8IVB4
ENSG00000181804ENST00000474151C9IZP1
ENSG00000181804ENST00000474727F8WF83

Expression (GTEx)

0
5
10
15
20
25
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Transmembrane transport of small moleculesREACTOMER-HSA-382551
SLC-mediated transmembrane transportREACTOMER-HSA-425407
Transport of inorganic cations/anions and amino acids/oligopeptidesREACTOMER-HSA-425393
Sodium/Proton exchangersREACTOMER-HSA-425986

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
188215652008Genome-wide association scan of quantitative traits for attention deficit hyperactivity disorder identifies novel associations and confirms candidate gene associations.133
192682762009Genome-wide association study of smoking initiation and current smoking.77
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
215555182011The BTB and CNC homology 1 (BACH1) target genes are involved in the oxidative stress response and in control of the cell cycle.60
189372942008Genome-wide association scan of the time to onset of attention deficit hyperactivity disorder.41
211716502011Organellar Na+/H+ exchangers: novel players in organelle pH regulation and their emerging functions.34
235081272014Genes for endosomal NHE6 and NHE9 are misregulated in autism brains.23
219085192011Polymorphisms in B3GAT1, SLC9A9 and MGAT5 are associated with variation within the human plasma N-glycome of 3533 European adults.19
200328192010Genetic variants in SLC9A9 are associated with measures of attention-deficit/hyperactivity disorder symptoms in families.16
200328192010Genetic variants in SLC9A9 are associated with measures of attention-deficit/hyperactivity disorder symptoms in families.16

Citation

Dessen P

SLC9A9 (solute carrier family 9 member A9)

Atlas Genet Cytogenet Oncol Haematol. 2016-04-01

Online version: http://atlasgeneticsoncology.org/gene/55706/slc9a9