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SLC9B2 (solute carrier family 9 member B2)

Identity

Alias_namesNHEDC2
Na?? exchanger domain containing 2
solute carrier family 9, subfamily B (cation proton antiporter 2), member 2
solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2
Alias_symbol (synonym)FLJ23984
NHA2
Other aliasNHE10
HGNC (Hugo) SLC9B2
LocusID (NCBI) 133308
Atlas_Id 41169
Location 4q24  [Link to chromosome band 4q24]
Location_base_pair Starts at 103025491 and ends at 103077371 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
TAB2 (6q25.1) / SLC9B2 (4q24)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SLC9B2   25143
Cards
Entrez_Gene (NCBI)SLC9B2  133308  solute carrier family 9 member B2
AliasesNHA2; NHE10; NHEDC2
GeneCards (Weizmann)SLC9B2
Ensembl hg19 (Hinxton)ENSG00000164038 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000164038 [Gene_View]  chr4:103025491-103077371 [Contig_View]  SLC9B2 [Vega]
ICGC DataPortalENSG00000164038
TCGA cBioPortalSLC9B2
AceView (NCBI)SLC9B2
Genatlas (Paris)SLC9B2
WikiGenes133308
SOURCE (Princeton)SLC9B2
Genetics Home Reference (NIH)SLC9B2
Genomic and cartography
GoldenPath hg38 (UCSC)SLC9B2  -     chr4:103025491-103077371 -  4q24   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SLC9B2  -     4q24   [Description]    (hg19-Feb_2009)
EnsemblSLC9B2 - 4q24 [CytoView hg19]  SLC9B2 - 4q24 [CytoView hg38]
Mapping of homologs : NCBISLC9B2 [Mapview hg19]  SLC9B2 [Mapview hg38]
OMIM611789   
Gene and transcription
Genbank (Entrez)AA233228 AK172823 AK297010 AK298506 AK299888
RefSeq transcript (Entrez)NM_001300754 NM_001300756 NM_178833
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SLC9B2
Cluster EST : UnigeneHs.546482 [ NCBI ]
CGAP (NCI)Hs.546482
Alternative Splicing GalleryENSG00000164038
Gene ExpressionSLC9B2 [ NCBI-GEO ]   SLC9B2 [ EBI - ARRAY_EXPRESS ]   SLC9B2 [ SEEK ]   SLC9B2 [ MEM ]
Gene Expression Viewer (FireBrowse)SLC9B2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)133308
GTEX Portal (Tissue expression)SLC9B2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86UD5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86UD5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86UD5
Splice isoforms : SwissVarQ86UD5
PhosPhoSitePlusQ86UD5
Domains : Interpro (EBI)Cation/H_exchanger    NHA2   
Domain families : Pfam (Sanger)Na_H_Exchanger (PF00999)   
Domain families : Pfam (NCBI)pfam00999   
Conserved Domain (NCBI)SLC9B2
DMDM Disease mutations133308
Blocks (Seattle)SLC9B2
SuperfamilyQ86UD5
Human Protein AtlasENSG00000164038
Peptide AtlasQ86UD5
HPRD14051
IPIIPI00478842   IPI00386475   IPI00915832   IPI00922341   IPI00922842   IPI00966494   IPI00968138   
Protein Interaction databases
DIP (DOE-UCLA)Q86UD5
IntAct (EBI)Q86UD5
FunCoupENSG00000164038
BioGRIDSLC9B2
STRING (EMBL)SLC9B2
ZODIACSLC9B2
Ontologies - Pathways
QuickGOQ86UD5
Ontology : AmiGOmonovalent cation:proton antiporter activity  mitochondrial inner membrane  plasma membrane  sodium ion transport  endosome membrane  lithium:proton antiporter activity  sodium:proton antiporter activity  integral component of membrane  basolateral plasma membrane  flagellated sperm motility  synaptic vesicle membrane  mitochondrial membrane  ion transmembrane transport  sodium ion transmembrane transport  identical protein binding  regulation of insulin secretion involved in cellular response to glucose stimulus  clathrin-dependent endocytosis  sperm principal piece  hydrogen ion transmembrane transport  positive regulation of osteoclast development  
Ontology : EGO-EBImonovalent cation:proton antiporter activity  mitochondrial inner membrane  plasma membrane  sodium ion transport  endosome membrane  lithium:proton antiporter activity  sodium:proton antiporter activity  integral component of membrane  basolateral plasma membrane  flagellated sperm motility  synaptic vesicle membrane  mitochondrial membrane  ion transmembrane transport  sodium ion transmembrane transport  identical protein binding  regulation of insulin secretion involved in cellular response to glucose stimulus  clathrin-dependent endocytosis  sperm principal piece  hydrogen ion transmembrane transport  positive regulation of osteoclast development  
NDEx NetworkSLC9B2
Atlas of Cancer Signalling NetworkSLC9B2
Wikipedia pathwaysSLC9B2
Orthology - Evolution
OrthoDB133308
GeneTree (enSembl)ENSG00000164038
Phylogenetic Trees/Animal Genes : TreeFamSLC9B2
HOVERGENQ86UD5
HOGENOMQ86UD5
Homologs : HomoloGeneSLC9B2
Homology/Alignments : Family Browser (UCSC)SLC9B2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSLC9B2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SLC9B2
dbVarSLC9B2
ClinVarSLC9B2
1000_GenomesSLC9B2 
Exome Variant ServerSLC9B2
ExAC (Exome Aggregation Consortium)SLC9B2 (select the gene name)
Genetic variants : HAPMAP133308
Genomic Variants (DGV)SLC9B2 [DGVbeta]
DECIPHERSLC9B2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSLC9B2 
Mutations
ICGC Data PortalSLC9B2 
TCGA Data PortalSLC9B2 
Broad Tumor PortalSLC9B2
OASIS PortalSLC9B2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSLC9B2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSLC9B2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SLC9B2
DgiDB (Drug Gene Interaction Database)SLC9B2
DoCM (Curated mutations)SLC9B2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SLC9B2 (select a term)
intoGenSLC9B2
Cancer3DSLC9B2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611789   
Orphanet
MedgenSLC9B2
Genetic Testing Registry SLC9B2
NextProtQ86UD5 [Medical]
TSGene133308
GENETestsSLC9B2
Target ValidationSLC9B2
Huge Navigator SLC9B2 [HugePedia]
snp3D : Map Gene to Disease133308
BioCentury BCIQSLC9B2
ClinGenSLC9B2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD133308
Chemical/Pharm GKB GenePA162397515
Clinical trialSLC9B2
Miscellaneous
canSAR (ICR)SLC9B2 (select the gene name)
Probes
Litterature
PubMed11 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSLC9B2
EVEXSLC9B2
GoPubMedSLC9B2
iHOPSLC9B2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 17:15:00 CEST 2017

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