Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

SLCO1A2 (solute carrier organic anion transporter family member 1A2)

Identity

Alias_namesSLC21A3
solute carrier family 21 (organic anion transporter), member 3
solute carrier organic anion transporter family, member 1A2
Alias_symbol (synonym)OATP
OATP1A2
OATP-A
Other alias
HGNC (Hugo) SLCO1A2
LocusID (NCBI) 6579
Atlas_Id 50582
Location 12p12.1  [Link to chromosome band 12p12]
Location_base_pair Starts at 21417534 and ends at 21487832 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
LIN7C (11p14.1) / SLCO1A2 (12p12.1)PSTK (10q26.13) / SLCO1A2 (12p12.1)SH3BP5 (3p25.1) / SLCO1A2 (12p12.1)
SLCO1A2 (12p12.1) / HP1BP3 (1p36.12)SLCO1A2 (12p12.1) / PPY (17q21.31)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SLCO1A2   10956
Cards
Entrez_Gene (NCBI)SLCO1A2  6579  solute carrier organic anion transporter family member 1A2
AliasesOATP; OATP-A; OATP1A2; SLC21A3
GeneCards (Weizmann)SLCO1A2
Ensembl hg19 (Hinxton)ENSG00000084453 [Gene_View]  chr12:21417534-21487832 [Contig_View]  SLCO1A2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000084453 [Gene_View]  chr12:21417534-21487832 [Contig_View]  SLCO1A2 [Vega]
ICGC DataPortalENSG00000084453
TCGA cBioPortalSLCO1A2
AceView (NCBI)SLCO1A2
Genatlas (Paris)SLCO1A2
WikiGenes6579
SOURCE (Princeton)SLCO1A2
Genetics Home Reference (NIH)SLCO1A2
Genomic and cartography
GoldenPath hg19 (UCSC)SLCO1A2  -     chr12:21417534-21487832 -  12p12.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)SLCO1A2  -     12p12.1   [Description]    (hg38-Dec_2013)
EnsemblSLCO1A2 - 12p12.1 [CytoView hg19]  SLCO1A2 - 12p12.1 [CytoView hg38]
Mapping of homologs : NCBISLCO1A2 [Mapview hg19]  SLCO1A2 [Mapview hg38]
OMIM602883   
Gene and transcription
Genbank (Entrez)AF085224 AF279784 AK296044 AK316249 BC042452
RefSeq transcript (Entrez)NM_005075 NM_021094 NM_134431
RefSeq genomic (Entrez)NC_000012 NC_018923 NT_009714 NW_004929383
Consensus coding sequences : CCDS (NCBI)SLCO1A2
Cluster EST : UnigeneHs.46440 [ NCBI ]
CGAP (NCI)Hs.46440
Alternative Splicing GalleryENSG00000084453
Gene ExpressionSLCO1A2 [ NCBI-GEO ]   SLCO1A2 [ EBI - ARRAY_EXPRESS ]   SLCO1A2 [ SEEK ]   SLCO1A2 [ MEM ]
Gene Expression Viewer (FireBrowse)SLCO1A2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6579
GTEX Portal (Tissue expression)SLCO1A2
Protein : pattern, domain, 3D structure
UniProt/SwissProtP46721   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP46721  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP46721
Splice isoforms : SwissVarP46721
PhosPhoSitePlusP46721
Domaine pattern : Prosite (Expaxy)KAZAL_2 (PS51465)    MFS (PS50850)   
Domains : Interpro (EBI)Kazal_dom    MFS_dom    OA_transporter   
Domain families : Pfam (Sanger)Kazal_2 (PF07648)    OATP (PF03137)   
Domain families : Pfam (NCBI)pfam07648    pfam03137   
Domain families : Smart (EMBL)KAZAL (SM00280)  
Conserved Domain (NCBI)SLCO1A2
DMDM Disease mutations6579
Blocks (Seattle)SLCO1A2
SuperfamilyP46721
Human Protein AtlasENSG00000084453
Peptide AtlasP46721
HPRD09112
IPIIPI00008254   IPI00220618   IPI00925159   IPI00925616   IPI00925835   IPI00788717   IPI00925875   IPI00926126   IPI00926317   IPI00926553   IPI00926789   IPI01009933   IPI01009491   
Protein Interaction databases
DIP (DOE-UCLA)P46721
IntAct (EBI)P46721
FunCoupENSG00000084453
BioGRIDSLCO1A2
STRING (EMBL)SLCO1A2
ZODIACSLCO1A2
Ontologies - Pathways
QuickGOP46721
Ontology : AmiGOplasma membrane  integral component of plasma membrane  bile acid metabolic process  organic anion transmembrane transporter activity  bile acid transmembrane transporter activity  bile acid transmembrane transporter activity  sodium-independent organic anion transmembrane transporter activity  organic anion transport  bile acid and bile salt transport  sodium-independent organic anion transport  sodium-independent organic anion transport  mitophagy in response to mitochondrial depolarization  
Ontology : EGO-EBIplasma membrane  integral component of plasma membrane  bile acid metabolic process  organic anion transmembrane transporter activity  bile acid transmembrane transporter activity  bile acid transmembrane transporter activity  sodium-independent organic anion transmembrane transporter activity  organic anion transport  bile acid and bile salt transport  sodium-independent organic anion transport  sodium-independent organic anion transport  mitophagy in response to mitochondrial depolarization  
Pathways : KEGGBile secretion   
NDEx NetworkSLCO1A2
Atlas of Cancer Signalling NetworkSLCO1A2
Wikipedia pathwaysSLCO1A2
Orthology - Evolution
OrthoDB6579
GeneTree (enSembl)ENSG00000084453
Phylogenetic Trees/Animal Genes : TreeFamSLCO1A2
HOVERGENP46721
HOGENOMP46721
Homologs : HomoloGeneSLCO1A2
Homology/Alignments : Family Browser (UCSC)SLCO1A2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSLCO1A2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SLCO1A2
dbVarSLCO1A2
ClinVarSLCO1A2
1000_GenomesSLCO1A2 
Exome Variant ServerSLCO1A2
ExAC (Exome Aggregation Consortium)SLCO1A2 (select the gene name)
Genetic variants : HAPMAP6579
Genomic Variants (DGV)SLCO1A2 [DGVbeta]
DECIPHER (Syndromes)12:21417534-21487832  ENSG00000084453
CONAN: Copy Number AnalysisSLCO1A2 
Mutations
ICGC Data PortalSLCO1A2 
TCGA Data PortalSLCO1A2 
Broad Tumor PortalSLCO1A2
OASIS PortalSLCO1A2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSLCO1A2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSLCO1A2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SLCO1A2
DgiDB (Drug Gene Interaction Database)SLCO1A2
DoCM (Curated mutations)SLCO1A2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SLCO1A2 (select a term)
intoGenSLCO1A2
Cancer3DSLCO1A2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602883   
Orphanet
MedgenSLCO1A2
Genetic Testing Registry SLCO1A2
NextProtP46721 [Medical]
TSGene6579
GENETestsSLCO1A2
Huge Navigator SLCO1A2 [HugePedia]
snp3D : Map Gene to Disease6579
BioCentury BCIQSLCO1A2
ClinGenSLCO1A2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6579
Chemical/Pharm GKB GenePA328
Clinical trialSLCO1A2
Miscellaneous
canSAR (ICR)SLCO1A2 (select the gene name)
Probes
Litterature
PubMed48 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSLCO1A2
EVEXSLCO1A2
GoPubMedSLCO1A2
iHOPSLCO1A2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 13:28:06 CET 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.